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Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors2021 Cancers article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer Open access
Jin Ma, Jiang Ren, Midory Thorikay, Maarten van Dinther, Gonzalo Sánchez‐Duffhues, Josselin Caradec, +3 more
10citations -
Cell-type-specific function of c-Jun N-terminal kinases (JNKs) determines the cholestasis activity in murine model2021 Zeitschrift für Gastroenterologie conference-paper Medicine Liver physiology and pathology Open access
Mohamed Ramadan Mohamed, Yulia Alexandrowna Nevzorova, Johannes Haybaeck, M.V. Boekschoten, Peter Boor, Pavel Strnad, +4 more
0citations -
Ste20-like Kinase Is Critical for Inhibitory Synapse Maintenance and Its Deficiency Confers a Developmental Dendritopathy2021 Journal of Neuroscience article Neuroscience Neuroscience and Neuropharmacology Research Open access cited by 2 patents
Susanne Schoch, Anne Quatraccioni, Barbara K. Robens, Robert Maresch, Karen M. J. van Loo, Silvia Cases‐Cunillera, +6 more
8citations -
Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate Improves Host Control of Salmonella enterica Serovar Typhimurium Infection in Human Macrophages2021 Frontiers in Immunology article Agricultural and Biological Sciences Salmonella and Campylobacter epidemiology Open access
Cassandra L. R. van Doorn, Gina K. Schouten, Suzanne van Veen, Kimberley V. Walburg, Jeroen J. Esselink, Matthias T. Heemskerk, +2 more
19citations -
Glucose-dependent miR-125b is a negative regulator of β-cell function2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Rebecca Cheung, Grazia Pizza, PAULINE L. CHABOSSEAU, Delphine Rolando, Alejandra Tomás, Thomas Burgoyne, +18 more
2citations -
The Tyrosine Kinase Tec Regulates Effector Th17 Differentiation, Pathogenicity, and Plasticity in T-Cell-Driven Intestinal Inflammation2021 Frontiers in Immunology article Immunology and Microbiology Psoriasis: Treatment and Pathogenesis Open access
Lisa Sandner, Marlis Alteneder, Ci Zhu, Anastasiya Hladik, Sandra Högler, Ramona Rîca, +8 more
13citations -
Pan-Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Abel Sousa, Aurélien J. F. Dugourd, Danish Memon, Borgþór Pétursson, Evangelia Petsalaki, Julio Sáez-Rodríguez, +1 more
6citations -
Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial2021 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
Bernard G Combe, Alan Kivitz, Yoshiya Tanaka, Désirée M F M van der Heijde, Jesus Abraham Simón Campos, Herbert S. B. Baraf, +14 more
248citations -
Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial2021 Acta Orthopaedica article Medicine Musculoskeletal synovial abnormalities and treatments Open access
Michiel A. J. van de Sande, William D. Tap, Heather L. Gelhorn, Xin Ye, Rebecca M. Speck, Emanuela Palmerini, +9 more
24citations -
Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines2021 Annals of Surgical Treatment and Research article Medicine Thyroid Cancer Diagnosis and Treatment Open access
Kyoung Sik Park, Madhuri Saindane, Eun Yeol Yang, Tong Yi Jin, Harikrishna Reddy Rallabandi, Alexander Heil, +7 more
7citations -
Renal dysfunction and podocyturia in pre-eclampsia may be explained by increased urinary VEGF2021 Nephrology Dialysis Transplantation article Medicine Pregnancy and preeclampsia studies Open access
Luca Valsecchi, Alessandro Galdini, Daniela Gabellini, Giacomo DellʼAntonio, Silvia Galbiati, Andrea Fanecco, +6 more
11citations -
International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome2021 Journal of Allergy and Clinical Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access cited by 2 patents
Dimana Dimitrova, Zohreh Nademi, Maria Elena Maccari, Stephan R. Ehl, Gülbû Uzel, Takahiro Tomoda, +48 more
74citations -
Phosphatidylserine Supplementation as a Novel Strategy for Reducing Myocardial Infarct Size and Preventing Adverse Left Ventricular Remodeling2021 International Journal of Molecular Sciences article Medicine Cardiac Ischemia and Reperfusion Open access
David Schumacher, Adelina Curaj, Mareike Staudt, Franziska Cordes, Andreea-Ramona Dumitrașcu, Benjamin Rolles, +7 more
26citations -
GlcNAc is a mast-cell chromatin-remodeling oncometabolite that promotes systemic mastocytosis aggressiveness2021 Blood article Immunology and Microbiology Mast cells and histamine Open access cited by 1 patent
Julie Agopian, Quentin Da Costa, Quang Vo Nguyen, Giulia Scorrano, Paraskevi Kousteridou, Min Yuan, +11 more
6citations -
Activated PI3Kδ syndrome, an immunodeficiency disorder, leads to sensorimotor deficits recapitulated in a murine model2021 Brain Behavior & Immunity - Health article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Ines Serra, Olivia R. Manusama, Fabian M. P. Kaiser, Izi Izumi Floriano, Lucas F Wahl, Christian van der Zalm, +8 more
14citations -
Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial2021 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
René Westhovens, William F. C. Rigby, Désirée M F M van der Heijde, D. W. T. CHING, William Stohl, Jonathan Kay, +13 more
150citations -
ST6Gal1 targets the ectodomain of ErbB2 in a site-specific manner and regulates gastric cancer cell sensitivity to trastuzumab2021 Oncogene article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Henrique O. Duarte, Joana G. Rodrigues, Catarina Gomes, Paul J. Hensbergen, Agnes L. Hipgrave Ederveen, Arnoud H. de Ru, +9 more
65citations