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Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors2020 Bone article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access cited by 13 patents
Gonzalo Sánchez‐Duffhues, Eleanor Williams, Marie‐José Goumans, Carl‐Henrik Heldin, Peter ten Dijke
118citations -
Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors2021 Cancers article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer Open access
Jin Ma, Jiang Ren, Midory Thorikay, Maarten van Dinther, Gonzalo Sánchez‐Duffhues, Josselin Caradec, +3 more
10citations -
Loss of c‐Jun N‐terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma2020 Hepatology Communications article Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Francisco Javier Cubero, Mohamed Ramadan Mohamed, Marius Maximilian Woitok, Gang Zhao, Maximilian Hatting, Yulia Alexandrowna Nevzorova, +7 more
29citations -
Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro2022 Frontiers in Cardiovascular Medicine article Medicine Parathyroid Disorders and Treatments Open access
Marina Augusto Heuschkel, Anne Babler, Jonas Heyn, Emiel P. C. van der Vorst, Marja Steenman, Maren Gesper, +8 more
20citations -
Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer2020 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access
Daan P. Hurkmans, Els M.E. Verdegaal, Sabrina A. Hogan, Rik de Wijn, Lies Hovestad, Dianne M. A. van den Heuvel, +15 more
21citations -
614PCANYON trial results: sevasemten, an investigational fast skeletal myosin inhibitor, reduced muscle damage biomarkers and stabilized function in BMD2025 Neuromuscular Disorders article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders
C. McDonald, Hani A. Kushlaf, Diana Castro, K. Mathews, Aveen Connolly, Michela Guglieri, +9 more
0citations -
The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K+ channel Kv1.1 through protein kinase C delta2020 BMC Biology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Yuemin Tian, Patricia Korn, Priyanka Tripathi, Daniel Komnig, Dominik Wiemuth, Azadeh Nikouee, +5 more
7citations -
Jaw-specific differential kinase activity profiles in human periodontal ligament stem cells under mechanical compression2025 Stem Cell Research & Therapy article Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Christian Niederau, Sanne Lidewij Maas, Emiel P. C. van der Vorst, Leon J. Schurgers, Yang Shi, Frank Hölzle, +2 more
3citations -
Research-based flow cytometry assays for pathogenic assessment in the human B-cell biology of gene variants revealed in the diagnosis of inborn errors of immunity: a Bruton’s tyrosine kinase case-study2023 Frontiers in Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Lucía del Pino Molina, Yolanda Soto Serrano, Keren Reche Yebra, J. Marty Lobo, B. González Martínez, María Bravo García‐Morato, +3 more
4citations -
Ste20-like Kinase Is Critical for Inhibitory Synapse Maintenance and Its Deficiency Confers a Developmental Dendritopathy2021 Journal of Neuroscience article Neuroscience Neuroscience and Neuropharmacology Research Open access cited by 2 patents
Susanne Schoch, Anne Quatraccioni, Barbara K. Robens, Robert Maresch, Karen M. J. van Loo, Silvia Cases‐Cunillera, +6 more
8citations -
Longitudinal Assessment of Creatine Kinase, Creatine/Creatinineratio, and Myostatin as Monitoring Biomarkers in Becker Muscular Dystrophy2022 Neurology article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Nienke M. van de Velde, Zaïda Koeks, Mirko Signorelli, Nisha E. Verwey, Maurice Overzier, Jaap Adriaan Bakker, +7 more
23citations -
TGF-β receptor-specific NanoBRET Target Engagement in living cells for high-throughput kinase inhibitor screens2024 SLAS DISCOVERY article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Marius Wits, Nicole Haarmans, Gonzalo Sánchez‐Duffhues, Marie‐José Goumans
3citations -
Phosphatidylinositol 4-Kinase IIIβ: A Therapeutic Target for Contractile Dysfunction in Hypertrophic Cardiomyocytes2026 International Journal of Molecular Sciences article Medicine Cardiomyopathy and Myosin Studies Open access
Myrthe M. A. Willemars, Aomin Sun, Shujin Wang, Özlenen Şimşek Papur, Agnieszka Brouns‐Strzelecka, Rick van Leeuwen, +6 more
0citations -
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration2024 Molecular Oncology article Biochemistry, Genetics and Molecular Biology Mechanisms of cancer metastasis Open access
Jennifer R. Kosinski, Antonio S. Sechi, Sophia Villwock, Stefanie Anh Ha, Maximilian Hauschulz, Michael Rose, +12 more
14citations -
Induction of Antimicrobial Protein S100A15 Expression by Oral Microbial Pathogens Is Toll-like Receptors-Dependent Activation of c-Jun-N-Terminal Kinase (JNK), p38, and NF-κB Pathways2023 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology S100 Proteins and Annexins Open access
Denis Selimović, Naji Kharouf, Florence Carrouel, Sofie-Yasmin Hassan, Thomas Wayne Flanagan, Sarah-Lilly Hassan, +4 more
4citations