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Polyelectrolyte Coating of Ferumoxytol Differentially Impacts on Labeling of Inflammatory and Steady-State Dendritic Cell Subtypes2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering Characterization and Applications of Magnetic Nanoparticles Open access
Nehar Celikkin, John Erik Wong, Martin Zenke, Thomas Hieronymus
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Inflammatory signature and restriction of adaptive immunity are associated with unfavorable outcomes on immune checkpoint blockade in patients with advanced head and neck squamous cell carcinoma
Lisa Paschold, Christoph Schultheiß, Paul Schmidt-Barbo, Konrad Friedrich Klinghammer, Dennis Hahn, Mareike Tometten, +8 more
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LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Nadia Cobo‐Vuilleumier, Silvia Rodríguez-Fernández, Livia López–Noriega, Petra Isabel Lorenzo, JM Franco, CC Lachaud, +22 more
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The cell cycle regulator Cyclin E1 drives macrophage-associated inflammatory responses in acute immune-mediated hepatitis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Christian Penners, Cheng Lin, Alexander Jans, Antje Mohs, Frank Tacke, Matthias Bartneck, +2 more
1citations -
Eicosapentaenoic acid induces an anti-inflammatory transcriptomic landscape in T cells implicating a pathway independent of triglyceride lowering in cardiovascular risk reduction2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Nursing Fatty Acid Research and Health Open access
Nathalie A. Reilly, Koen F. Dekkers, Jeroen Molenaar, Sinthuja Arumugam, Thomas B. Kuipers, Yavuz Ariyürek, +3 more
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Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Tyrosine Phosphatases Open access
Maja Šolman, Sasja Blokzijl-Franke, Florian Piques, Chuan Yan, Qiqi Yang, Marion Strullu, +6 more
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Enhanced inflammatory response mediated by parenchymal cells associates with resistance towards mTOR inhibition2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Long R. Jiao, Roman Eickhoff, Sandra Jumpertz, Merve Erdem, Andreas Kroh, Hans Duimel, +6 more
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Cigarette smoke induces PPP1R15A via oxidative stress to modulate inflammatory cytokine production by bronchial epithelial cells2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Gimano D. Amatngalim, Anne Margaretha van der Does, Maria Concetta Zarcone, Elke Malzer, Jayson Bradley, Maria Gabriela Belvisi, +4 more
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Oleic acid triggers CD4 + T cells to be metabolically rewired and poised to differentiate into proinflammatory T cell subsets upon activation2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Nathalie A. Reilly, Friederike Sonnet, Koen F. Dekkers, Joanneke C. Kwekkeboom, Lucy Sinke, Stan T. Hilt, +8 more
1citations -
Single-cell characterization of human periodontal ligament (PDL) cells reveals uniformly mesenchymal populations in matched maxilla and mandible pairs from four donors2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Periodontal Regeneration and Treatments Open access
Chloé Radermacher, Robert Dzhanaev, Christian Hasberg, Sabine Neuß-Stein, Andrea Gorgels, Julia Moellmann, +8 more
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Multimodal single-cell analysis uncovers transcription factor networks underlying T-cell aging2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Mina Shaigan, Deepika Puri, Giulia Fornero, René Krüger, Mara Steiger, Hannes Klump, +4 more
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Tissue-embedded CD4⁺ plasticity defines mucosal immunity in Inflammatory Bowel Disease2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Qinyue Jiang, Veerle A. Merkus, Ciska Lindelauf, Laura F. Ouboter, Thomas Höllt, Philip W. Voorneveld, +5 more
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A 37-color spectral flow cytometry panel to characterize phenotype and cytokine expression in human intestinal T cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Ciska Lindelauf, Qinyue Jiang, Frits Koning, Andrea E. van der Meulen‐de Jong, Vincent van Unen, María Fernanda Pascutti
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A scalable tumor-vasculature-on-chip for CAR T cell trafficking and efficacy studies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Luuk de Haan, Aleksandra Olczyk, Thomas Olivier, Joris Wesselius, Johnny Suijker, Claudia Al-Mardini, +3 more
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Pericytes promote more angiogenesis and vasculogenesis than mesenchymal stromal cells in microfluidic chips2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer Open access
Julian Gonzalez‐Rubio, Hannah Kubiza, Hiltrud Koenigs‐Werner, Stefan Jockenhoevel, Christian Gabriel Cornelissen, Anja Lena Thiebes
2citations -
Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 3 patents
Hamsa Narasimhan, Maria Lucia Richter, Ramin Shakiba, Nikos E. Papaioannou, Christina Stehle, Isabel Ulmert, +12 more
5citations -
Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Parasites and Host Interactions Open access
Anna Zawistowska‐Deniziak, Joost M. Lambooij, Alicja Kalinowska, Thiago A. Patente, Maciej Łapiński, Hendrik J.P. van der Zande, +9 more
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Validation of an MPS based intestinal cell culture model for the evaluation of drug-induced toxicity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Stefanie Hoffmann, Philip Hewitt, Isabel Koscielski, Dorota Kurek, Wouter Strijker, Kinga Kosim
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SMAD2: Regulatory junction of TGF-β and antigen signaling in mast cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Gina Bronneberg, Steffen K. Meurer, Marlies Kauffmann, Chao‐Chung Kuo, Christian Liedtke, Ralf Weiskirchen, +1 more
1citations -
TNFR2 costimulation differentially impacts regulatory and conventional CD4 + T-cell metabolism2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Mark Mensink, Esther A. Zaal, Thi Tran Ngoc Minh, Ellen Schrama, Celia R. Berkers, Jannie G. Borst, +1 more
0citations