Papers matching “immune checkpoint blockade” 20
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Inflammatory signature and restriction of adaptive immunity are associated with unfavorable outcomes on immune checkpoint blockade in patients with advanced head and neck squamous cell carcinoma
Lisa Paschold, Christoph Schultheiß, Paul Schmidt-Barbo, Konrad Friedrich Klinghammer, Dennis Hahn, Mareike Tometten, +8 more
0citations -
γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Natasja L. De Vries, Joris van de Haar, Vivien Veninga, Myriam Chalabi, Marieke E. Ijsselsteijn, Manon van der Ploeg, +8 more
3citations -
P2RY2 is a purinergic immune checkpoint linking extracellular ATP to immune evasion and adaptive resistance to immunotherapy2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Zhaoqing Hu, Shangce Du, Cecilia Berzain Battioni, Lena Jassowicz, Rafael Carretero, Melanie Sator‐Schmitt, +8 more
2citations -
Myeloid reprogramming by JAK inhibition enhances checkpoint blockade therapy2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune cells in cancer Open access
Jaroslav Žák, Isaraphorn Pratumchai, Brett S. Marro, Kristi Marquardt, Reza Beheshti Zavareh, Luke L. Lairson, +4 more
6citations -
Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Noah F. Greenwald, Iris Nederlof, Daisy Yi Ding, Seongyeol Park, Alex Kong, Kathleen E. Houlahan, +29 more
7citations -
OX40 agonism enhances efficacy of PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Guillaume Beyrend, Tetje Cornelia van der Sluis, Esmé T.I. van der Gracht, Tamim Abdelaal, Simon P. Jochems, Robert A. Belderbos, +16 more
0citations -
Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Óscar Lapuente-Santana, Gregor Sturm, Markus Außerhofer, Constantin Zackl, Maria Zopoglou, Nicholas McGranahan, +5 more
0citations -
The MHC-E Peptide Ligand of Checkpoint NKG2A Is Governed by Inflammatory Signals and High Turnover2023 SSRN Electronic Journal preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Jim Middelburg, Soroush Ghaffari, Tom A. W. Schoufour, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, +14 more
0citations -
A lymph node-to-tumour PDL1 + macrophage circuit antagonizes dendritic cell immunotherapy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immunotherapy and Immune Responses Open access
Jenny Sprooten, Isaure Vanmeerbeek, Angeliki Datsi, Jannes Govaerts, Daniel Borràs, Stefan Naulaerts, +17 more
4citations -
CMAS dampens anti-tumor immunity and associates with response to neoadjuvant immunotherapy in melanoma2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Magalí B. Coccimiglio, Sofia Ibáñez‐Molero, Babet O. Springer, Laura J. W. Kruijssen, Georgia Clayton, Reece Davison, +17 more
0citations -
Immune infiltration is linked to increased transcriptional activity and distinct metabolic profiles in chordomas2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Bone Tumor Diagnosis and Treatments Open access
Siddh van Oost, Rick Ursem, Zeynep Betül Erdem, Sanne Venneker, Ruud van der Breggen, Inge H. Briaire‐de Bruijn, +8 more
0citations -
TIGIT drives the immunosuppressive environment by downregulation of metalloproteinases MMP2 and MMP14 in perihilar cholangiocarcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Lara Rosaline Heij, Konrad Reichel, Willem de Koning, Jan Bednarsch, Xiuxiang Tan, Julia Campello Deierl, +13 more
0citations -
A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology IL-33, ST2, and ILC Pathways Open access
Graham A. Heieis, Bart Everts, Craig W. Roberts, Rick M. Maizels, Georgia Perona‐Wright
1citations -
Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Katrin Raute, Juliane Strietz, Geoffroy Andrieux, Oliver S. Thomas, Klaus M. Kistner, Marina Zintchenko, +7 more
0citations
20 results