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AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and mice2021 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Emin Onur Karakaslar, Muneer G. Hasham, Neerja Katiyar, Ahrim Youn, Siddhartha Sharma, Cheng‐Han Chung, +4 more
0citations -
Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and human2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Juan-Felipe Perez-Correa, Vithurithra Tharmapalan, Hartmut Geiger, Wolfgang Wagner
2citations -
Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Yi Ding, Robert-Jan Raterink, Rubén Marín‐Juez, Wouter J. Veneman, Koen Egbers, Susan J. F. van den Eeden, +7 more
2citations -
SysQuan: repurposing SILAC mice for the affordable absolute quantitation of the human proteome2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Chemistry Advanced Proteomics Techniques and Applications
Yassene Mohammed, Vincent R. Richard, M. Immanuel Reyes Madlangsakay, Ying Lao, Victor Spicer, Claudia Gaither, +4 more
0citations -
LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Nadia Cobo‐Vuilleumier, Silvia Rodríguez-Fernández, Livia López–Noriega, Petra Isabel Lorenzo, JM Franco, CC Lachaud, +22 more
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A human GBA-L444P transgene drives early and persistent dopamine neurotransmission deficits and alpha-synuclein pathology in a mouse model of early Parkinson’s disease2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Lysosomal Storage Disorders Research Open access
Natalie Connor‐Robson, Tara Diviney, Javier Alegre‐Abarrategui, Katherine R. Brimblecombe, Nora Bengoa‐Vergniory, Harrison Waters, +7 more
0citations -
Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Trygve E. Bakken, Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach, +94 more
89citations -
Alternating hemiplegia of childhood associated mutations in Atp1a3 reveal diverse neurological alterations in mice2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Epilepsy research and treatment Open access
Markus Terrey, Georgii Krivoshein, Scott I. Adamson, Elena Arystarkhova, Laura C. Anderson, John Szwec, +13 more
2citations -
Tau phosphorylated at serine 356 is associated with Alzheimer’s disease pathology and can be lowered in mouse and human brain tissue using the NUAK inhibitor WZ40032023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Alzheimer's disease research and treatments Open access
Lewis W. Taylor, Elizabeth M. Simzer, Claire Pimblett, Oscar T. T. Lacey-Solymar, Robert I. McGeachan, Jamie L. Rose, +10 more
2citations -
Mice alternate between discrete strategies during perceptual decision-making2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Visual perception and processing mechanisms Open access
Zoe C. Ashwood, Iris R. Stone, Anne E Urai, Anne K. Churchland, Alexandre Pouget, Jonathan W. Pillow
38citations -
The extent of myeloid skewing in blood is a biomarker of biological aging in mice and humans2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Hematopoietic Stem Cell Transplantation Open access
Julian Niemann, Selina Stahl, Vadim Sakk, Juan-Felipe Perez-Correa, Wolfgang Wagner, Andrea Jaensch, +5 more
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MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Disease Diagnosis and Treatment Open access
Linsey J. F. Peters, Leonida Rakateli, Rosanna Huchzermeier, Andrea Bonnin-Marquez, Sanne Lidewij Maas, Cheng Lin, +18 more
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Scalable production of tissue-like vascularised liver organoids from human PSCs2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Sean Philip Harrison, Richard Siller, Yoshiaki Tanaka, Yangfei Xiang, Benjamin Patterson, Henning Kempf, +22 more
12citations -
Tofacitinib fails to prevent T cell transfer colitis in mice but ameliorates disease activity2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Sudheendra Hebbar Subramanyam, Judit Turyne Hrcziko, Angeliki Pappas, Angela Schippers, Kim Ohl, Klaus Tenbrock
0citations -
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Farooq Syed, Olivia Ballew, Chih‐Chun Lee, Jyoti Rana, Preethi Krishnan, Ângela Castela, +16 more
3citations -
Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Environmental Science Bacteriophages and microbial interactions Open access
Alexandra von Strempel, Anna S. Weiß, Johannes Wittmann, Marta Salvado Silva, Diana Ring, Esther Wortmann, +4 more
2citations -
The adhesion molecules β7 integrin and L-selectin contribute to cholestatic liver disease in male mice2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Diseases and Immunity Open access
Anshu Babbar, Sreepradha Eswaran, Moritz Muschaweck, Nicole Simone Treichel, Thomas Clavel, Adrien Guillot, +3 more
0citations -
Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Milena Schönke, Zhixiong Ying, Artemiy Kovynev, Wietse In het Panhuis, Anne Binnendijk, Sabine van der Poel, +5 more
3citations -
KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Lohr, Rossella Pellegrino, Mihael Vucur, Michael T. Singer, Veronika Buettner, +7 more
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Identification of endothelial-to-mesenchymal transition gene signatures in single-cell transcriptomics of human atherosclerotic tissue2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Lotte Slenders, Marian Wesseling, Arjan Boltjes, Daniek Kapteijn, Marie A.C. Depuydt, Koen H.M. Prange, +8 more
6citations -
The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type-2 immunity-independent inhibition of food intake2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Parasites and Host Interactions Open access
Hendrik J.P. van der Zande, Karin de Ruiter, Ruud H. P. Wilbers, Noemí García‐Tardón, Mariska van Huizen, Kim van Noort, +14 more
13citations