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HLA-Restriction of Human Treg Cells Is Not Required for Therapeutic Efficacy of Low-Dose IL-2 in Humanized Mice2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Rajeev Kumar Tyagi, Justin Jacobse, Jing Li, Margaret M. Allaman, Kevin L. Otipoby, Erik R. Sampson, +2 more
22citations -
Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system2024 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Xiaojing Tina Chen, Matthias Leisegang, Ioannis Gavvovidis, Seth M. Pollack, Felix K.M. Lorenz, Ton N. Schumacher, +2 more
6citations -
Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141+ Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8+ T Cell Response in Human Immune System Mice2020 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Jing Huang, Jing Zhou, Reem Ghinnagow, Toshiyuki Seki, Sho Iketani, Daphnée Soulard, +5 more
27citations -
Intranasal multivalent adenoviral-vectored vaccine protects against replicating and dormant M.tb in conventional and humanized mice2023 npj Vaccines article Medicine Tuberculosis Research and Epidemiology Open access cited by 1 patent
Sam Afkhami, Michael R. D’Agostino, Maryam Vaseghi‐Shanjani, Madeleine Lepard, Jack X. Yang, Rocky Lai, +8 more
26citations -
AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and mice2021 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Emin Onur Karakaslar, Muneer G. Hasham, Neerja Katiyar, Ahrim Youn, Siddhartha Sharma, Cheng‐Han Chung, +4 more
0citations -
The Human Milk Oligosaccharide 2′-Fucosyllactose Alleviates Liver Steatosis, ER Stress and Insulin Resistance by Reducing Hepatic Diacylglycerols and Improved Gut Permeability in Obese Ldlr-/-.Leiden Mice
Eveline Gart, Kanita Salic, Martine C. Morrison, Martin A. Giera, Joline Attema, Christa de Ruiter, +5 more
25citations -
Recombinant human proteoglycan 4 lowers inflammation and atherosclerosis susceptibility in female low‐density lipoprotein receptor knockout mice2024 The Journal of Physiology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Menno Hoekstra, Olga S.C. Snip, Philip Janusz, Mireia N. A. Bernabé Kleijn, Edward R. Truitt, Benjamin David Sullivan, +3 more
3citations -
High-intensive therapeutic lowering of systemic cholesterol does not ameliorate osteoarthritis development in knee joints of humanized dyslipidemic mice2020 Osteoarthritis and Cartilage article Medicine Osteoarthritis Treatment and Mechanisms Open access
Yvonne van Gemert, A.E. Kozijn, Marianne G. Pouwer, N.N.L. Kruisbergen, M.H. van den Bosch, Arjen B. Blom, +4 more
0citations -
Development of autonomic innervation at the venous pole of the heart: bridging the gap from mice to human2025 Journal of Translational Medicine article Medicine Heart Rate Variability and Autonomic Control Open access
Fleur Zwanenburg, Arend D.J. ten Harkel, Monique C. Haak, Nathan D. Hahurij, Robert E. Poelmann, Conny J. van Munsteren, +4 more
3citations -
Epigenetic Clocks for Mice Based on Age-Associated Regions That are Conserved Between Mouse Strains and Human2022 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Juan-Felipe Perez-Correa, Vithurithra Tharmapalan, Hartmut Geiger, Wolfgang Wagner
20citations -
Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and human2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Juan-Felipe Perez-Correa, Vithurithra Tharmapalan, Hartmut Geiger, Wolfgang Wagner
2citations -
HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice2024 International Journal of Molecular Sciences article Medicine HER2/EGFR in Cancer Research Open access
Veruschka Albert, Christina Bruß, Deniz Tümen, Gerhard Piendl, Florian Weber, Edgar Dahl, +4 more
7citations -
Human milk oligosaccharide 2’-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and faecal proteome profiles in mice
Paola Paone, Dimitrios Latousakis, Romano Terrasi, Didier Vertommen, Ching Jian, Valentina Borlandelli, +12 more
69citations -
Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Yi Ding, Robert-Jan Raterink, Rubén Marín‐Juez, Wouter J. Veneman, Koen Egbers, Susan J. F. van den Eeden, +7 more
2citations -
The human intestinal bacterium Eggerthella lenta influences gut metabolomes in gnotobiotic mice2024 Microbiome Research Reports article Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Alina Viehof, Sven‐Bastiaan Haange, Theresa Streidl, Kristin A. Schubert, Beatrice Engelmann, Dirk Haller, +3 more
6citations -
SysQuan: Repurposing SILAC Mice for the Cost-Effective Absolute Quantitation of the Human Proteome2025 Molecular & Cellular Proteomics article Chemistry Advanced Proteomics Techniques and Applications Open access
Yassene Mohammed, Vincent R. Richard, M. Immanuel Reyes Madlangsakay, Ying Lao, Victor Spicer, Claudia Gaither, +4 more
4citations -
SysQuan: repurposing SILAC mice for the affordable absolute quantitation of the human proteome2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Chemistry Advanced Proteomics Techniques and Applications
Yassene Mohammed, Vincent R. Richard, M. Immanuel Reyes Madlangsakay, Ying Lao, Victor Spicer, Claudia Gaither, +4 more
0citations -
Novel short-termed mouse model of intrahepatic cholangiocarcinoma by orthotopic transplantation of Hep-55.1C in mice with human homology2022 Zeitschrift für Gastroenterologie article Medicine Cholangiocarcinoma and Gallbladder Cancer Studies
TheresaHildegard Wirtz, Elisa Fabiana Brandt, Petra Fischer, Christian H. Holland, A Röth, Maike Baues, +7 more
0citations