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Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Niels van den Berg, Mar Rodríguez‐Girondo, Ingrid K. van Dijk, P. Eline Slagboom, Marian Beekman
21citations -
Increasing number of long-lived ancestors associates with up to a decade of healthspan extension and a healthy metabolomic profile in mid-life2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Niels van den Berg, Mar Rodríguez‐Girondo, Ingrid K. van Dijk, P. Eline Slagboom, Marian Beekman
1citations -
The plasma proteins GSN, F2, CRTAC1, and HP reflect multigenerational health, longevity, and resilience2026 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Pasquale C. Putter, Marian Beekman, Nico Lakenberg, Stefan Müller, Roman‐Ulrich Müller, Joris Deelen, +3 more
1citations -
Multivariate genomic scan implicates novel loci and haem metabolism in human ageing2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access cited by 2 patents
Paul R. H. J. Timmers, James F. Wilson, Peter K. Joshi, Joris Deelen
145citations -
Similar burden of pathogenic coding variants in exceptionally long‐lived individuals and individuals without exceptional longevity2020 Aging Cell article Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases Open access cited by 1 patent
Danielle Gutman, Gabriel Arie Lidzbarsky, Sofiya Milman, Tina Gao, Patrick Sin‐Chan, Claudia G. Gonzaga-Jauregui, +4 more
13citations -
Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics2025 Drug Design Development and Therapy article Medicine Telomeres, Telomerase, and Senescence Open access
Esther Ugo Alum, Sylvester Chibueze Izah, Daniel Ejim Uti, Okechukwu Paul-Chima Ugwu, Peter Aniah Betiang, Mariam Basajja, +1 more
57citations -
Rare longevity-associated variants, including a reduced-function mutation in cGAS, identified in multigenerational long-lived families2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Pasquale C. Putter, Di Guan, Thies Gehrmann, Daniel Kolbe, Jiping Yang, HyeRim Han, +13 more
2citations -
Microvesicle-Mediated Tissue Regeneration Mitigates the Effects of Cellular Ageing2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Dagmara McGuiness, Armand M. G. Jaminon, Barend M.E. Mees, Colin Selman, Leon J. Schurgers, Paul G. Shiels
0citations -
Challenges and recommendations for the translation of biomarkers of aging2024 Nature Aging article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Chiara Maria Stella Herzog, Ludger J.E. Goeminne, Jesse R. Poganik, Nir Barzilai, Daniel W. Belsky, Joe Betts-LaCroix, +28 more
108citations -
Roadmap for alleviating the manifestations of ageing in the cardiovascular system2025 Nature Reviews Cardiology review Medicine Cardiovascular Health and Disease Prevention Open access
Luca Liberale, Simon Tual‐Chalot, Simon Sedej, Stefano Ministrini, Georgios A. Georgiopoulos, Myriam Grunewald, +55 more
58citations -
Design of the VOILA-intervention study: A 12-week nutrition and resistance exercise intervention in metabolic or mobility compromised Dutch older adults and the response on immune-metabolic, gut and muscle health parameters2024 Mechanisms of Ageing and Development article Medicine Nutrition and Health in Aging Open access cited by 1 patent
Alejandra P. Monsegue, Jordi Morwani‐Mangnani, Pol Grootswagers, Marian Beekman, P. Eline Slagboom, Lex B. Verdijk, +1 more
4citations -
Immune aging biomarkers for clinical trials2026 Nature Medicine article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms
Andrea Cipriano, Jamie Nicole Justice, Jesse R. Poganik, Mahdi Moqri, Omar O. Abudayyeh, Jonathan S. Gootenberg, +17 more
1citations -
Mortality prediction by a metabolomics score and health- and lifestyle-related factors combined2026 medRxiv preprint Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Kerstin Schorr, Mar Rodríguez Girondo, Lisette C. P. G. M. de Groot, P. Eline Slagboom, Marian Beekman
1citations -
The genomics of exceptional longevity in rockfishes refine genetic foundations of human lifespan variation2021 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Stephen B. Treaster, Joris Deelen, Jacob M. Daane, Joanne M. Murabito, David Karasik, Matthew P. Harris
0citations -
Microvesicle-Mediated Tissue Regeneration Mitigates the Effects of Cellular Ageing2023 Cells article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Dagmara McGuinness, Armand M. G. Jaminon, Barend M.E. Mees, Colin Selman, Leon J. Schurgers, Paul G. Shiels
1citations -
Rare genetic variants in the IIS/mTOR signalling pathway identified in exceptionally long-lived individuals show shared in vitro effects associated with lifespan across species2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Mara Neuerburg, Larissa Smulders, Erik B. van den Akker, Daniel Kolbe, Filippo Artoni, Isabell Brusius, +10 more
0citations -
Penalized reduced rank regression for multi-outcome survival data supports a common metabolic risk score for age-related diseases2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Mathematics Statistical Methods and Inference Open access
Marije H. Sluiskes, Hein Putter, Marian Beekman, Jelle J. Goeman, Mar Rodríguez‐Girondo
0citations
18 results