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Targeting the Kv11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives2020 European Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Jacobus P. D. van Veldhoven, Giulia Campostrini, Constantijn J.E. van Gessel, Dorien Ward‐van Oostwaard, Rongfang Liu, Christine L. Mummery, +2 more
7citations -
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology2021 Journal of Cheminformatics article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Xuhan Liu, Kai Ye, Herman van Vlijmen, Michael Emmerich, Adriaan P. IJzerman, Gerard J. P. van Westen
118citations -
Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias2020 Stem Cell Reports article Medicine Cardiac electrophysiology and arrhythmias Open access cited by 1 patent
Karina O. Brandão, Lettine van den Brink, Duncan C. Miller, Catarina Grandela, Berend J. van Meer, Mervyn P.H. Mol, +6 more
44citations -
Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance2022 Human Molecular Genetics article Medicine Cardiac electrophysiology and arrhythmias Open access
Jaël S. Copier, Marianne Bootsma, Chai‐Ann Ng, Arthur A.M. Wilde, Robin A. Bertels, Hennie Bikker, +12 more
5citations -
Safety pharmacology in 2022: Taking one small step for cardiovascular safety assay development but one giant leap for regulatory drug safety assessment2022 Journal of Pharmacological and Toxicological Methods article Medicine Cardiac electrophysiology and arrhythmias Open access
Michael K. Pugsley, Yevgeniya E. Koshman, Tessa de Korte, Simon Authier, Brett R. Winters, Michael J. Curtis
2citations -
Radio-AGN activity across the galaxy population: dependence on stellar mass, star formation rate, and redshift2024 Monthly Notices of the Royal Astronomical Society article Physics and Astronomy Galaxies: Formation, Evolution, Phenomena Open access
R. Kondapally, P. N. Best, K. J. Duncan, Huub J. A. Röttgering, Daniel J. B. Smith, Isabella Prandoni, +13 more
11citations -
The DESI view of the faint radio source population in LoTSS DR22026 Monthly Notices of the Royal Astronomical Society article Physics and Astronomy Galaxies: Formation, Evolution, Phenomena Open access
M I Arnaudova, L. R. Holden, D J B Smith, P. N. Best, R. Kondapally, K. J. Duncan, +7 more
0citations -
The environments of radio galaxies and quasars in LoTSS data release 22025 Springer Link (Chiba Institute of Technology) article Physics and Astronomy Galaxies: Formation, Evolution, Phenomena Open access
T. Pan, Y. Fu, H. J. A. Rottgering, Reinout J. van Weeren, Alyssa B. Drake, B. H. Yue, +1 more
0citations -
The LOFAR two metre sky survey data release 2: probabilistic spectral source classifications and faint radio source demographics2024 Monthly Notices of the Royal Astronomical Society article Physics and Astronomy Galaxies: Formation, Evolution, Phenomena Open access
Alyssa B. Drake, Daniel J. B. Smith, M. J. Hardcastle, P. N. Best, R. Kondapally, M I Arnaudova, +5 more
14citations -
The LOFAR Two-metre Sky Survey Deep Fields: new probabilistic spectroscopic classifications and the accretion rates of radio galaxies2025 Monthly Notices of the Royal Astronomical Society article Physics and Astronomy Galaxies: Formation, Evolution, Phenomena Open access
M I Arnaudova, Daniel J. B. Smith, M. J. Hardcastle, P. N. Best, Soumyadeep Das, Shravya Shenoy, +5 more
8citations
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