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FLAG-X: Hybrid machine learning workflows for automated gating of clinical flow cytometry data2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Paul Martini, Marziyeh Mohammadi, Michael Christoph Thrun, David B. Blumenthal, Stefan W. Krause
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A 37-color spectral flow cytometry panel to characterize phenotype and cytokine expression in human intestinal T cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Ciska Lindelauf, Qinyue Jiang, Frits Koning, Andrea E. van der Meulen‐de Jong, Vincent van Unen, María Fernanda Pascutti
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Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Dennis Hoving, A.H.C. Marques, Wesley Huisman, Beckley A. Nosoh, Alicia C. de Kroon, Oscar R. J. van Hengel, +8 more
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Autoreactive B cells in rheumatoid arthritis consist of activated CXCR3+ memory B cells and plasmablasts2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Sanne Reijm, Joanneke C. Kwekkeboom, Nienke J. Blomberg, Jolien Suurmond, Diane van der Woude, René E. M. Toes, +1 more
1citations -
Immuno-functionomics reveals geographical variation and a role for TLR8 in mRNA vaccine responses2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune responses and vaccinations Open access
Wesley Huisman, Shohreh Azimi, Thi Yen Nhi Nguyen, Alicia C. de Kroon, Karin de Ruiter, Dicky L. Tahapary, +9 more
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Using network component analysis to study axenisation strategies for phototrophic eukaryotic microalgae2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protist diversity and phylogeny Open access
Ajay Balu Iyer, Matthias Monissen, Oskar Modin, Ronald Halim
0citations -
Development of an Affinity-Based Probe to profile endogenous Human Adenosine A3 Receptor Expression2023 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Bert L. H. Beerkens, Inge M. Snijders, Joep Snoeck, Rongfang Liu, Anton T. J. Tool, Sylvia E. Le Dévédec, +6 more
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Nanoparticle size governs engagement with myeloid cells and hitchhiking to hematopoietic organs in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Materials Science Nanoparticle-Based Drug Delivery Open access
Sara Elsafy, Shiva Khorshid, Alessia Nucci, Federica De Lorenzi, Alessandro Motta, Margherita Vieri, +11 more
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QUAS-R: Glutamine (Q) Uptake Assay with Single cell Resolution reveals metabolic heterogeneity with immune populations2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Amino Acid Enzymes and Metabolism Open access
Leonard R. Pelgrom, Simon O’Shoughnessy, Sander van Kasteren, David K. Finlay, Linda V. Sinclair
5citations -
Bivalent COVID-19 vaccines boost the capacity of pre-existing SARS-CoV-2-specific memory B cells to cross-recognize Omicron subvariants2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Holly A. Fryer, Daryl Geers, Lennert Gommers, Luca M. Zaeck, Ngoc H. Tan, Bernadette Jones, +10 more
1citations -
The cell cycle regulator Cyclin E1 drives macrophage-associated inflammatory responses in acute immune-mediated hepatitis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Christian Penners, Cheng Lin, Alexander Jans, Antje Mohs, Frank Tacke, Matthias Bartneck, +2 more
1citations -
Investigating T cell Recruitment in Atherosclerosis using a novel Human 3D Tissue-Culture Model reveals the role of CXCL12 in intraplaque neovessels2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Laura Parma, Nadja Sachs, Zhaolong Adrian Li, Nikola Sobczak, Bram Slütter, Lars Mäegdefessel, +3 more
1citations -
Pharmacological depletion of microglia prevents vascular cognitive impairment in Ang II-induced hypertension2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neurological Disease Mechanisms and Treatments Open access
Daniëlle Kerkhofs, Britt T. van Hagen, Irina V. Milanova, Kimberly J Schell, Helma van Essen, Erwin Wijnands, +7 more
1citations -
Microglial Response in Triggering Receptor Expressed on Myeloid Cells 2 (Trem2) Knock-out Mice After Systemic Stimulation With Escherichia Coli2022 Research Square preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Inge C.M. Hoogland, Jutka Yik, Dunja Westhoff, Joo-Yeon Engelen-Lee, Merche Valls Seron, Wing Kit Man, +6 more
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Longitudinal dynamics of human B-cell response at single-cell level in response to Tdap vaccination2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Indu Khatri, Annieck M. Diks, Erik B. van den Akker, Liesbeth E.M. Oosten, Jaap Jan Zwaginga, Marcel J. T. Reinders, +2 more
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Fluorescence-activated cell sorting of Escherichia coli L-forms reveals maintained synchronized nucleic acid synthesis dynamics2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access
Marjolein E. Crooijmans, Johannes H. DE WINDE, Dennis Claessen
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Aspergillus -mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype, a process that can be targeted via antifungal therapeutics2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Asthma and respiratory diseases Open access
Emma L. Houlder, Sara Gago, George Vere, David Conn, Sheeba Khan, MW Shepherd, +5 more
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Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Suzanne M. Castenmiller, Nandhini Kanagasabesan, Aurélie Guislain, Benoît P. Nicolet, Marleen M. van Loenen, Kim Monkhorst, +6 more
0citations