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Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Chen‐Yi Liao, Jasmijn H.M. Hundscheid, Justin Crawford, Peter ten Dijke, Beatrice Coorneaert, Erik H.J. Danen
0citations -
Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tendon Structure and Treatment Open access
Jolet Y. Mimpen, Mathew J. Baldwin, Claudia Paul, Lorenzo Ramos‐Mucci, Alina Kurjan, C. Cohen, +9 more
5citations -
Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Junedh Amrute, In‐Hyuk Jung, Tracy Yamawaki, Andrea L. Bredemeyer, Johanna Diekmann, Sikander Hayat, +28 more
5citations -
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, +16 more
1citations -
Single-cell characterization of human periodontal ligament (PDL) cells reveals uniformly mesenchymal populations in matched maxilla and mandible pairs from four donors2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Periodontal Regeneration and Treatments Open access
Chloé Radermacher, Robert Dzhanaev, Christian Hasberg, Sabine Neuß-Stein, Andrea Gorgels, Julia Moellmann, +8 more
0citations -
IntraTalker - Modelling Intracellular Signalling in Cellular Crosstalk2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Vanessa Klöker, James S. Nagai, Z. Feng, Lampros Mavrommatis, Larissa Hermanns, Jacqueline Michelle Jara Moscoso, +3 more
1citations -
Matrix stiffness affects spheroid invasion, collagen remodeling and the effective reach of stress into the ECM2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions
Klara Beslmüller, Rick Rodrigues de Mercado, Gijsje Hendrika Koenderink, Erik H.J. Danen, Thomas Schmidt
2citations -
Hierarchical and context-dependent GR-MR signalling governs endogenous corticosteroid decoding in the heart2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Francesca Sacchi, Stefano Boriati, Rocco Caliandro, Silvia Da Pra, Irene Del Bono, Azra Husetić, +10 more
0citations -
TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Stephen E. White, Tristin A. Schwartze, Ananya Mukundan, Christina Schoenherr, Shashi Prakash Singh, Maarten van Dinther, +9 more
5citations -
Aberrant and Ectopic Cell Populations of the Fibrotic Pushing Border in Restrictive Allograft Syndrome after Lung Transplantation2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Transplantation: Methods and Outcomes Open access
Lena Maureen Leiber, Leonard Christian, Lavinia Neubert, Jannik Ruwisch, Hande Yilmaz, Edith Katharina Plucinski, +22 more
2citations -
Modulating effects of FGF12 variants on Na V 1.2 and Na V 1.6 associated with Developmental and Epileptic Encephalopathy and Autism Spectrum Disorder2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simone Seiffert, Manuela Pendziwiat, Tatjana Bierhals, Himanshu Goel, Niklas Schwarz, Amelie T. van der Ven, +5 more
2citations -
A multicenter spatial transcriptomics atlas of human tuberculosis and non-tuberculous mycobacterial disease2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Xun Jiang, Leonard Christian, Liang Zhou, Nienke van Unen, Lavinia Neubert, Jan C. Kamp, +13 more
2citations -
Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B -related neurodevelopmental disorders2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Chromatin Remodeling and Cancer Open access
Luca Pagliaroli, Patrizia Porazzi, Alyxandra T. Curtis, Chiara Scopa, Harald M. M. Mikkers, Lucia Daxinger, +8 more
1citations -
Mechanotranscriptomic Profiling of Breast Cancer Cells Intravasated from Engineered Microtumors2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
René Krüger, Miguel Fuentes‐Chandía, Helly Atiya, Angeles De La Cruz, Sadaf Pashapour, Aldo Roberto Boccaccini, +5 more
0citations -
TGFβ signaling in cancer-associated fibroblasts drives a hepatic gp130-dependent pro-metastatic inflammatory program in CMS4 colorectal cancer subtype2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Tom J. Harryvan, Subinuer Abudukelimu, Imke Stouten, EJ van der Wel, Kristiaan Lenos, OJ Sansom, +1 more
0citations -
Assembly defects of the human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Samoil Sekulovski, Pascal Devant, Silvia Panizza, Tasos Gogakos, Anda Pitiriciu, Katharina Heitmeier, +7 more
7citations -
A simplified co-culture reveals altered cardiotoxic responses to doxorubicin in hPSC-derived cardiomyocytes in the presence of endothelial cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
Marcella Brescia, Andrea Chatrian, Paul Keselman, James Gallant, Elsa Sorman Paulsson, Mervyn P.H. Mol, +10 more
1citations -
Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Dylan Mostert, Bart G. W. Groenen, Leda Klouda, Robert C. J. J. Passier, Marie‐José Goumans, Nicholas A. Kurniawan, +1 more
1citations -
Synthesis of EPD, an established cytotoxic agent for ovarian cancer cells, and its efficacy in cisplatin and paclitaxel resistant tumor cells2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Sesquiterpenes and Asteraceae Studies Open access
Caroline van Haaften, Jan H. Koek, Jaap D. H. van Eendenburg, Wolter ten Hoeve
0citations