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Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design2022 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Eerappa Rajakumara, Suman Abhishek, Kulhar Nitin, Dubey Saniya, Priyanka Bajaj, Ulrich Schwaneberg, +1 more
47citations -
Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies2026 Angewandte Chemie International Edition article Medicine Lysosomal Storage Disorders Research Open access
Nicky de Koster, Òscar Vidal-Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, +8 more
1citations -
Mechanistic Investigations of Metallo-β-Lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
1citations -
Mechanistic Investigations of Metallo-β-Lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
0citations -
Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition**2021 ChemMedChem article Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
33citations -
Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α- l -Arabinofuranosidases2020 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Nicholas G. S. McGregor, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Mireille Haon, Jos Reijngoud, +9 more
50citations -
Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Gus D. Warren, Tomoe Kitao, Tyler G. Franklin, Justine V. Nguyen, Paul P. Geurink, Tomoko Kubori, +2 more
2citations -
The molecular basis and enzyme engineering strategies for improvement of coupling efficiency in cytochrome P450s2022 Biotechnology Advances article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Shuaiqi Meng, Yu Ji, Leilei Zhu, Gaurao V. Dhoke, Mehdi D. Davari, Ulrich Schwaneberg
49citations -
Efficient production of the anti-aging drug Cycloastragenol: insight from two Glycosidases by enzyme mining2020 Applied Microbiology and Biotechnology article Biochemistry, Genetics and Molecular Biology Enzyme Production and Characterization
Leiyu Cheng, Han Zhang, Haiyang Cui, Wenya Wang, Qipeng Yuan
16citations -
Investigating enzyme function by geometric matching of catalytic motifs2026 Protein Science article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
R. Hackett, Ioannis G. Riziotis, Martin F. Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton
0citations -
Conserved white-rot enzymatic mechanism for wood decay in the Basidiomycota genus Pycnoporus2020 DNA Research article Agricultural and Biological Sciences Enzyme-mediated dye degradation Open access
Shingo Miyauchi, Hayat Hage, Élodie Drula, Laurence Lesage‐Meessen, Jean‐Guy Berrin, David Navarro, +35 more
49citations -
Discovery and mechanism-guided engineering of BHET hydrolases for improved PET recycling and upcycling2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Anni Li, Yijie Sheng, Haiyang Cui, Minghui Wang, Luxuan Wu, Yibo Song, +3 more
112citations -
Investigating enzyme function by geometric matching of catalytic motifs2026 Zenodo (CERN European Organization for Nuclear Research) software Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Ioannis G. Riziotis, Martin F. Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton
0citations -
Visualizing the mechanism of quinol oxidation and inhibition of a bd -type oxidase using cryo-EM2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Materials Science Enzyme Structure and Function Open access
Tijn T. van der Velden, Kanwal Kayastha, Famke Pelser, Steffen Brünle, Lars J. C. Jeuken
0citations -
Investigating Enzyme Function by Geometric Matching of Catalytic Motifs2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Ioannis G. Riziotis, Martin F. Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton
2citations -
From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling2024 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Marta Artola, Johannes M. F. G. Aerts, Gijsbert A. van der Marel, Carme Rovira, Jeroen D. C. Codée, G.J. Davies, +1 more
26citations -
Multi-omic data fusion reveals the in vivo enzyme kinetics of Vibrio natriegens at the genome-scale2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
St. Elmo Wilken, Martin Beyß, Miroslav Kratochvíl, Alexa Grebel, Karen Methling, Anja Stefanski, +7 more
0citations