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Early integration of palliative care versus standard cardiac care for patients with heart failure (EPCHF): a multicentre, parallel, two-arm, open-label, randomised controlled trial2024 The Lancet Healthy Longevity article Medicine Palliative Care and End-of-Life Issues Open access
Mahmoud Balata, Lukas Radbruch, Michaela Hesse, Ralf Westenfeld, Martin Neukirchen, Roman Pfister, +9 more
14citations -
FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy – protocol for a prospective multicentre mixed-methods feasibility study
Asma A. Khalil, Smriti Prasad, Kerry Woolfall, Tracy Karen Mitchell, Jamie J Kirkham, Odai Yaghi, +39 more
5citations -
The death of a neurotrauma trial lessons learned from the prematurely halted randomized evaluation of surgery in elderly with traumatic acute subdural hematoma (RESET-ASDH) trial
Ranjit D. Singh, Jeroen T.J.M. van Dijck, Thomas Arjan van Essen, Hayden P. Nix, Rick Vreeburg, Hugo F. den Boogert, +3 more
6citations -
Levothyroxine in euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss (T4LIFE trial): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial2022 The Lancet Diabetes & Endocrinology article Medicine Thyroid Disorders and Treatments Open access
Marie‐Louise van der Hoorn, Ole Bjarne Christiansen, Madelon van Wely
95citations -
Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial
Jürgen Beck, Christian Fung, Daniel Strbian, Lukas Bütikofer, Werner Josef Z'Graggen, Matthias F. Lang, +43 more
126citations -
Granulocyte-colony stimulating factor (G-CSF) to treat acute-on-chronic liver failure: A multicenter randomized trial (GRAFT study)2021 Journal of Hepatology article Medicine Liver Disease and Transplantation Open access cited by 1 patent
Cornelius Engelmann, Adam Herber, Annegret Franke, Tony Bruns, Philipp Alexander Reuken, Ingolf Schiefke, +22 more
146citations -
A comparison of conservative versus surgical treatment in patients with foot drop due to peroneal nerve entrapment: results of a prematurely terminated randomized controlled trial
Christophe Oosterbos, Annie S. Dubuisson, Frank J. M. Weyns, Justus L Groen, Sophie Schuind, Rik Demaerel, +11 more
0citations -
Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial2023 American Journal of Respiratory and Critical Care Medicine article Medicine Respiratory Support and Mechanisms Open access
Lea Imeen van der Wal, Chloe C.A. Grim, Michael R. del Prado, David J. van Westerloo, E. Christiaan Boerma, Hilda G. Rijnhart-de Jong, +16 more
72citations -
Fosfomycin Vs Ciprofloxacin as Oral Step-Down Treatment for Escherichia coli Febrile Urinary Tract Infections in Women: A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial
Sander Kuiper, Cees van Nieuwkoop, Robert Jan Hassing, Suzan P. van Mens, Akke K. van der Bij, Suzanne E. Geerlings, +18 more
24citations -
Editor's Choice – Activated Clotting Time Guided Heparinisation during Open Abdominal Aortic Aneurysm Repair (ACTION-1): A Randomised, Multicentre, Single Blind, Superiority Trial2025 European Journal of Vascular and Endovascular Surgery article Medicine Aortic aneurysm repair treatments Open access
Vincent Jongkind, Thomas A H Steunenberg, Liliane C. Roosendaal, Max Hoebink, Jan D. Blankensteijn, Mark J.W. Koelemay, +16 more
9citations -
Second-Line Bosutinib Is Effective and Feasible in Patients Failing Second Generation TKI (2G-TKI) in Chronic Phase Chronic Myeloid Leukemia (CML) - an Analysis of a Subcohort of the Bodo Trial (CML-VII-study of the German CML Study Group)
Susanne Isfort, Kirsi Marjaana Manz, Lino Lars Teichmann, Martina Margrit Crysandt, Andreas Burchert, Andreas Hochhaus, +18 more
0citations -
Can we Save the rectum by watchful waiting or transanal microsurgery following shorT-course radiotherapy and Additional local oR systemic Treatment for early-stage REctal Cancer? STARTREC-3 protocol for a non-randomised, multicentre, phase II platform study
Suzanne E N De Vries, Alice M. Couwenberg, Corrie A.M. Marijnen, Geerard L. Beets, Jacobus W. A. Burger, Myriam Chalabi, +6 more
3citations -
Cardiotoxicity and Cardiovascular Biomarkers in Patients With Breast Cancer: Data From the GeparOcto‐GBG 84 Trial2020 Journal of the American Heart Association article Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
Alexandra Maria Rüger, Andreas Schneeweiß, Sabine Seiler, Hans Tesch, Marion van Mackelenbergh, Frederik Marmé, +14 more
38citations -
Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury
Alexander Zarbock, Mira Küllmar, Detlef Kindgen‐Milles, Carola Wempe, Joachim Gerß, Timo Brandenburger, +24 more
382citations