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Papers matching “cholesterol clearance” 24

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HEPATOCYTE-SPECIFIC DISRUPTION OF ABCA6 INCREASES (V)LDL CHOLESTEROL AND AGGRAVATES ATHEROSCLEROSIS BY ATTENUATING LDL RECEPTOR-MEDIATED CHOLESTEROL CLEARANCE
2026 Atherosclerosis article Medicine Cholesterol and Lipid Metabolism

Xiaoke Ge, Kelsey Jarrett, Liv Tybjærg Nordestgaard, Xue Yang, Sander Kooijman, Yanan Wang, +4 more

0

citations
Obicetrapib Alone and in Combination with Ezetimibe Reduces Non-HDL-Cholesterol by Enhanced LDL-Receptor-Mediated VLDL Clearance and Increased Net Fecal Sterol Excretion in ApoE*3-Leiden.CETP Mice
2024 American Heart Journal article Medicine Lipoproteins and Cardiovascular Health

José A. Inia, Nanda Keijzer, Nicole Worms, Anita van Nieuwkoop, Marc Ditmarsch, J. Wouter Jukema, +3 more

0

citations
Obicetrapib alone and in combination with ezetimibe reduces non-HDL-cholesterol by enhanced LDL-receptor-mediated VLDL clearance and increased net fecal sterol excretion in apoe*3-leiden.cetp mice
2024 Atherosclerosis article Medicine Lipoproteins and Cardiovascular Health Open access

José A. Inia, Nanda Keijzer, Nicole Worms, Anita van Nieuwkoop, Marc Ditmarsch, J. Wouter Jukema, +5 more

1

citations
Obicetrapib and ezetimibe enhance LDL receptor-mediated VLDL clearance and regress atherosclerosis on atorvastatin background
2026 Journal of Lipid Research article Medicine Lipoproteins and Cardiovascular Health Open access

José A. Inia, Leo H. Zhang, Nanda Keijzer, Nicole Worms, Anita van Nieuwkoop, Marc Ditmarsch, +8 more

2

citations
CETP inhibition enhances monocyte activation and bacterial clearance and reduces streptococcus pneumonia–associated mortality in mice
2024 JCI Insight article Medicine Sepsis Diagnosis and Treatment Open access cited by 1 patent

Haoyu Deng, Wan Yi Liang, L. Chen, Tin Ho Yuen, Dragoş M. Vasilescu, Mark Trinder, +4 more

16

citations
Obicetrapib alone and in combination with ezetimibe increases reverse cholesterol transport and does not affect VLDL production
2025 Atherosclerosis article Medicine Cholesterol and Lipid Metabolism Open access

José A. Inia, Nanda Keijzer, Nicole Worms, Anita van Nieuwkoop, Marc Ditmarsch, J. Wouter Jukema, +4 more

0

citations
Targeting excessive cholesterol deposition alleviates secondary lymphoedema
2026 Nature article Medicine Lymphatic System and Diseases Open access

Hwee Ying Lim, Yuning Zhang, Syaza Hazwany Azhar, Chung Hwee Thiam, Michaela Taylor, Xuan Han Koh, +18 more

8

citations
Targeting excessive skin cholesterol deposition driven by lymphatic insufficiency alleviates secondary lymphedema
2024 Research Square preprint Medicine Lymphatic System and Diseases Open access

Véronique Angeli, Hwee Ying Lim, Syaza Hazwany Azhar, Mohamed Ameen Shah Bin Mohamed Yunos, Yuning Zhang, Chung Hwee Thiam, +11 more

0

citations
Resident LYVE-1+ macrophages contribute to endothelin-1 clearance and attenuate atherosclerosis via endothelin receptor B
2025 European Heart Journal article Medicine Nitric Oxide and Endothelin Effects

Sebastian Frederik Mause, H Lim, S Y Lim, Chung Hwee Thiam, C W Zhong, Jochen Grommes, +2 more

0

citations
Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis
2021 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Fibroblast Growth Factor Research Open access cited by 2 patents

Cong Liu, Milena Schönke, Enchen Zhou, Zhuang Li, Sander Kooijman, Mariëtte R. Boon, +7 more

85

citations
Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice
2021 Pharmacological Research article Medicine Lipoproteins and Cardiovascular Health Open access

Enchen Zhou, Zhuang Li, Hiroyuki Nakashima, Ahlam Choukoud, Sander Kooijman, Jimmy F.P. Berbée, +2 more

18

citations
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
2020 Diabetes Care article Medicine Diabetes Treatment and Management Open access

Roberto Bizzotto, Christopher Jennison, Angus G. Jones, Azra Kurbasic, Andrea Tura, Gwen Kennedy, +85 more

27

citations
Loss of the E3 ubiquitin ligase MARCHF6 alters hepatic lipid metabolism and drives spontaneous hepatosteatosis
2026 Molecular Metabolism article Medicine Liver Disease Diagnosis and Treatment Open access

Vinay Sachdev, Nienke M. van Loon, Jenina Kingma, Roelof Ottenhoff, Josephine M. E. Tan, Marlene van den Berg, +13 more

1

citations
A Novel Role for CETP as Immunological Gatekeeper: Raising HDL to Cure Sepsis?
2020 Trends in Endocrinology and Metabolism review Medicine Cholesterol and Lipid Metabolism

Lisanne L. Blauw, Yanan Wang, Ko Willems van Dijk, Patrick C.N. Rensen

40

citations
Stabilin 1 and 2 are important regulators for cellular uptake of apolipoprotein B-containing lipoproteins in zebrafish
2022 Atherosclerosis article Medicine Cholesterol and Lipid Metabolism Open access

Robin A.F. Verwilligen, Lindsay Mulder, Frans J. Rodenburg, Amy Van Dijke, Menno Hoekstra, Jeroen Bussmann, +1 more

16

citations
Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans
2022 Cardiovascular Research article Medicine Adipose Tissue and Metabolism Open access

Zhixiong Ying, Naomi Tramper, Enchen Zhou, Mariëtte R. Boon, Patrick C.N. Rensen, Sander Kooijman

43

citations
Hepatic Scavenger Receptor Class B Type 1 Knockdown Reduces Atherosclerosis and Enhances the Antiatherosclerotic Effect of Brown Fat Activation in APOE*3-Leiden.CETP Mice
2021 Arteriosclerosis Thrombosis and Vascular Biology article Medicine Cholesterol and Lipid Metabolism Open access

Enchen Zhou, Li Zhuang, Hiroyuki Nakashima, Cong Liu, Zhixiong Ying, Amanda C. Foks, +4 more

11

citations
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia
2022 Circulation article Medicine Lipid metabolism and disorders Open access cited by 1 patent

Wieneke Dijk, Mathilde Di Filippo, Sander Kooijman, Robin van Eenige, Antoine Rimbert, Amandine Caillaud, +16 more

24

citations
Liver-targeted Angptl4 silencing by antisense oligonucleotide treatment attenuates hyperlipidaemia and atherosclerosis development in APOE*3-Leiden.CETP mice
2024 Cardiovascular Research article Medicine Lipid metabolism and disorders Open access

Melanie Modder, Wietse In het Panhuis, Mohan Li, Salwa Afkir, Alexandra L Dorn, Amanda C. M. Pronk, +8 more

17

citations
Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins
2022 Arteriosclerosis Thrombosis and Vascular Biology article Medicine Cholesterol and Lipid Metabolism Open access

Dyonne Y. Vos, Melinde Wijers, Marieke Smit, Nicolette Huijkman, Niels Kloosterhuis, Justina Clarinda Wolters, +6 more

19

citations
Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway
2022 Pharmacological Research article Medicine Adipose Tissue and Metabolism Open access

Zhixiong Ying, Robin van Eenige, Rosa Beerepoot, Mariëtte R. Boon, Niels Kloosterhuis, Bart van de Sluis, +3 more

12

citations
Atherosclerosis: an overview of mouse models and a detailed methodology to quantify lesions in the aortic root
2024 Vascular Biology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

Jamie I. van der Vaart, Robin van Eenige, Patrick C.N. Rensen, Sander Kooijman

14

citations
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling
2024 Clinical Proteomics article Medicine Lipoproteins and Cardiovascular Health Open access

Esther Reijnders, Arnoud van der Laarse, L. Renee Ruhaak, Christa M. Cobbaert

10

citations
#2295 Characterization and standard of care efficacy testing in a translational mouse model of cardiovascular-kidney-metabolic syndrome
2025 Nephrology Dialysis Transplantation article Medicine Chronic Kidney Disease and Diabetes Open access

Arianne van Koppen, Anke M. Smits, Tri Quang Nguyen, Amélie Dendooven, Ingeborg M. Bajema, Harry van Goor, +5 more

0

citations

24 results