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Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Genetic Neurodegenerative Diseases Open access
Michael A. Margreiter, Monika Witzenberger, Yasmine Wasser, Elena Davydova, Robert Janowski, Carina Sobisch, +11 more
0citations -
Cell DiffErential Expression by Pooling (CellDEEP) highlights issues in differential gene expression in scRNA-seq2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Yiyi Cheng, Toby Kettlewell, Ross F Laidlaw, Olympia M Hardy, Andrew McCluskey, Thomas D. Otto, +1 more
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Omics studies of nuclear protein aggregates in subcellular fractions reveals co- aggregation of RNA-binding proteins affecting cytosolic pathways2025 Research Square preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Milad Shademan, Sarah E. Flannery, Erik Bos, Tom M. J. Evers, Vahid Sheikhhassani, Alireza Mashaghi, +5 more
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Reconstitution of human fetal ovaries reveals niche requirements for primordial germ cell-like cell progression2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm, Albert Blanch-Asensio, Arend W. Overeem, Susana M. Chuva de Sousa Lopes
2citations -
Distinct roles of IDR and CCD domains control PABPN1 aggregation and enable therapeutic rescue2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Milad Shademan, Iolanda Vendrell, Alberto Malerba, s Khoshbash, Sarah Flannery, March, +4 more
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Solid tumor-on-chip model for efficacy and safety assessment of CAR-T cell therapy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine CAR-T cell therapy research Open access
Tengku Ibrahim Maulana, Claudia Teufel, Madalena Cipriano, Lisa Lazarevski, Francijna E. van den Hil, Valeria V. Orlova, +4 more
2citations -
NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Paula Niewold, Marieke E. Ijsselsteijn, Karin Dijkman, Noel F.C.C. de Miranda, Tom H. M. Ottenhoff, Frank A. W. Verreck, +1 more
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The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Mohamed H. Elsafi Mabrouk, Roman Goetzke, Giulio Abagnale, Burcu Yesilyurt, Lucia Salz, Kira Zeevaert, +8 more
1citations -
High-resolution cryo-EM structure of integrin αIIbβ3 bound to disease-causing maternal HPA-1a antibody that blocks integrin activation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cell Adhesion Molecules Research Open access
José M. de Pereda, Wendy Stam, Marcos Gragera, Femke S. van der Meer, Francisco Javier Chichón, Eleftherios Zarkadas, +4 more
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A precise and general FRET-based method for monitoring structural transitions in protein self-organization2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Advanced Fluorescence Microscopy Techniques Open access
Qi Wan, Sara N. Mouton, Liesbeth M. Veenhoff, Arnold J. Boersma
7citations -
Multimodal profiling of chordoma immunity reveals distinct immune contextures2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Bone Tumor Diagnosis and Treatments Open access
Siddh van Oost, Debora M. Meijer, Marieke E. Ijsselsteijn, Jessica P Roelands, Ruud van der Breggen, Inge H. Briaire‐de Bruijn, +7 more
1citations -
Patient-derived monoclonal anti-HPA-1a can induce platelet activation through FcγRIIa2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Platelet Disorders and Treatments Open access
Janita J. Oosterhoff, Suze Rosanne van Brummelen, Marco Giulini, Iris M. De Cuyper, Remco Visser, Rick Kapur, +11 more
0citations -
Genetically-encoded probes to determine nonspecific hydrophobic and electrostatic binding in cells2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Advanced Fluorescence Microscopy Techniques Open access
Weiyan Zuo, Meng‐Ruo Huang, Fabian Schmitz, Arnold J. Boersma
2citations -
AAV-Delivered Anti-PC-OxPL Antibody Fragments: A Novel Therapeutic Approach to Target ALS2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Amyotrophic Lateral Sclerosis Research
Andreia Gomes‐Duarte, Jamie K. Wong, Svetlana Pasteuning-Vuhman, Wouter Pos, Rob Haselberg, Marina Sogorb-González, +6 more
1citations -
A Chemoenzymatic Strategy for Site-Specific Glyco-Tagging of Native Proteins for the Development of Biologicals2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Ana Gimeno, Anna M. Ehlers, Sandra Delgado, Jan-Willem H. Langenbach, Leendert J. van den Bos, John A. W. Kruijtzer, +2 more
0citations