Papers matching “cardiomyocyte contractility” 58
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A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness2020 Journal of Molecular and Cellular Cardiology article Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Marcelo C. Ribeiro, Rolf H. Slaats, Verena Schwach, José M. Rivera‐Arbeláez, Leon G.J. Tertoolen, Berend J. van Meer, +4 more
70citations -
VAE-MOTION: A deep generative model for cardiomyocyte contractility analysis for improving drug efficacy evaluation2025 Expert Systems with Applications article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Giorgia Curci, Paola Casti, Luca Sala, Marcella Brescia, Pasquale Cascarano, Michele D’Orazio, +6 more
2citations -
High-throughput contractility analysis platform for drug-response evaluation of hiPSC-derived cardiac models based on dynamic frequency conditioning2026 Biosensors and Bioelectronics article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Paola Casti, Marcella Brescia, Luca Sala, Arianna Mencattini, Massimo Mastrangeli, Berend J. van Meer, +1 more
1citations -
Evaluating a Novel Cell‐Free Preservation Solution for Human Cardiomyocyte Protection: A Proof‐of‐Concept Study2026 BioMed Research International article Medicine Transplantation: Methods and Outcomes Open access
Sandra Kraemer, Alexander Theißen, Merlin Kunze, Josefin Soppert, Leon J. Schurgers, Rogier J. A. Veltrop, +4 more
0citations -
Restoration of structural organization in engineered cardiac microtissues is promoted by cardiomyocyte beating2026 Communications Biology article Medicine Tissue Engineering and Regenerative Medicine Open access
Dylan Mostert, Hesam Hoursam, Marie‐José Goumans, R. C. Passier, Sandra Loerakker, Nicholas A. Kurniawan, +1 more
0citations -
Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes2020 Toxicological Sciences article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Umber Saleem, Berend J. van Meer, Puspita Anggraini Katili, Nurul Ain Nasim Mohd Yusof, Ingra Mannhardt, Ana Krotenberg García, +16 more
74citations -
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease2020 Cell stem cell article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 13 patents
Elisa Giacomelli, Viviana Meraviglia, Giulia Campostrini, Amy Cochrane, Xu Cao, Ruben W.J. van Helden, +23 more
643citations -
Human iPSC-cardiomyocyte-aggregate cell therapy in non-human primates and correlation of heart recovery with contractile and electrophysiological cardiomyocyte properties2026 Nature Communications article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Ina Gruh, Andreas Martens, Serghei Cebotari, Annette Schrod, Alexandra Haase, Caroline Halloin, +37 more
0citations -
YAP1 reactivation in cardiomyocytes following ECM remodelling contributes to the development of contractile force and sarcomere maturation2025 Cell Death Discovery article Biochemistry, Genetics and Molecular Biology Hippo pathway signaling and YAP/TAZ Open access
Vladimír Vinarský, Stefania Pagliari, Bacel Aldabash, Cristina Mazzotti, Katerina Jirakova, Zuzana Garlíková, +9 more
1citations -
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype2021 Science Translational Medicine article Medicine Tissue Engineering and Regenerative Medicine Open access
Jacqueline M. Bliley, Mathilde C. S. C. Vermeer, Rebecca M. Duffy, Ivan Batalov, Duco Kramer, Joshua W. Tashman, +17 more
135citations -
Sarcomere Disassembly and Transfection Efficiency in Proliferating Human iPSC-Derived Cardiomyocytes2022 Journal of Cardiovascular Development and Disease article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Qianliang Yuan, Renée G. C. Maas, Jiayi Pei, C. Snijders Blok, Marko A. Popovic, Nanne J. Paauw, +7 more
8citations -
Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy2023 Science Translational Medicine article Medicine Cardiovascular Effects of Exercise Open access cited by 1 patent
Hoyee Tsui, Sebastiaan J. van Kampen, Su Ji Han, Viviana Meraviglia, Willem B. van Ham, Simona Casini, +21 more
32citations -
Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format2020 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Ingra Mannhardt, Umber Saleem, Diogo Mosqueira, Malte Loos, Bärbel Maria Ulmer, Marc Daniel Lemoine, +8 more
74citations -
Metabolic environment in vivo as a blueprint for differentiation and maturation of human stem cell-derived cardiomyocytes22citations
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Acquired control over proliferation and differentiation of ventricular cardiomyocytes to break down the mechanisms of cardiac repair2024 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Ashna Ramkisoensing, Juan Zhang, Daniël A. Pijnappels, Antoine A.F. de Vries
0citations