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Scale-up of Streptomyces species cultivations based on the morphological response to the energy dissipation rate2026 RWTH Publications (RWTH Aachen) article Medicine Microbial Natural Products and Biosynthesis Open access
Gesa Brauneck, Anton Brass, Artiom Boreiko, Marvin Ueßeler, Johannes Pastoors, Valentin Steier, +6 more
0citations -
Leveraging overpressure to improve gas conversion in Methylococcus capsulatus scale-up fermentations2026 Biotechnology and Bioprocess Engineering article Agricultural and Biological Sciences Probiotics and Fermented Foods Open access
Dominik Engel, Tobias Jülich, Oliver Korves, Marcel Mann, Tino Schlepütz, Jørgen Magnus
1citations -
Leveraging overpressure to improve gas conversion in Methylococcus capsulatus scale-up fermentations2026 Biotechnology and Bioprocess Engineering article Agricultural and Biological Sciences Probiotics and Fermented Foods Open access
Dominik Olaf Klaus Engel, Tobias Jülich, Oliver Korves, Marcel Mann, Tino Schlepütz, Jørgen Barsett Magnus
0citations -
Thinking big in small scale: characterization of peroxidase production in Komagataella phaffii using two-compartment scale-down system2026 Bioprocess and Biosystems Engineering article Agricultural and Biological Sciences Enzyme-mediated dye degradation Open access
Christian Mathis Wagner, Katharina Schwartz, Anton Glieder, Wolfgang Wiechert, Marco Oldiges
0citations -
Machine learning in bioprocess development: From promise to practice2022 arXiv (Cornell University) preprint Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Laura M. Helleckes, Johannes Hemmerich, Wolfgang Wiechert, Eric von Lieres, Alexander Grünberger
4citations -
Microfluidic single-cell scale-down bioreactors: A proof-of-concept for the growth of Corynebacterium glutamicum at oscillating pH values2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Sarah Täuber, Luisa Blöbaum, Valentin Steier, Marco Oldiges, Alexander Grünberger
2citations -
Machine learning in bioprocess development: from promise to practice2022 Trends in biotechnology review Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access cited by 1 patent
Laura M. Helleckes, Johannes Hemmerich, Wolfgang Wiechert, Eric von Lieres, Alexander Grünberger
166citations -
Small-scale fed-batch cultivations of Vibrio natriegens: overcoming challenges for early process development2025 Bioprocess and Biosystems Engineering article Biochemistry, Genetics and Molecular Biology Enzyme Production and Characterization Open access
Clara Lüchtrath, Eva Forsten, Romeos Polis, Aylin Sara Genis, Marcel Hövels, Uwe Deppenmeier, +2 more
5citations -
COMPmodelpy: Understanding Microbial Metabolism in Bioreactors in a Compartment Modeling Framework2026 RWTH Publications (RWTH Aachen) conference-paper Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Samira van den Bogaard, Titania Insani Sugiarto, Tobias B. Alter, Lars M. Blank
0citations -
COMPmodelpy: Understanding Microbial Metabolism in Bioreactors in a Compartment Modeling Framework2026 Zenodo (CERN European Organization for Nuclear Research) article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Samira van den Bogaard, Titania Insani Sugiarto, Tobias B. Alter, Lars M. Blank
0citations -
Generating in-depth process knowledge by Computational Fluid Dynamics and a novel online monitoring technique for shake flasks0citations
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Simultaneous online monitoring of viscosity and oxygen transfer rate in shake flask cultures2025 Journal of Biological Engineering article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
René Hanke, Michaela Sieben, Maurice Finger, Kilian Schnoor, Simon Jeßberger, Julia Weyand, +5 more
2citations -
Validation of computational fluid dynamics of shake flask experiments at moderate viscosity by liquid distributions and volumetric power inputs2024 Scientific Reports article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Carl Dinter, Andreas Gumprecht, Matthias Alexander Menze, Amizon Azizan, Paul-Joachim Niehoff, Jochen Büchs
14citations -
Analysis across scales: Integrated insights in metabolism and economic feasibility of recombinant protein production from CO2 and H20citations
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Analysis across scales: Integrated insights in metabolism and economic feasibility of recombinant protein production from CO2 and H20citations
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Simulation-guided process intensification for methanotrophic Methylococcus capsulatus cultivation2026 Biochemical Engineering Journal article Biochemistry, Genetics and Molecular Biology Microbial metabolism and enzyme function Open access
Dominik Olaf Klaus Engel, Valentin Steier, Marcel Mann, Tino Schlepütz, Jørgen Barsett Magnus
0citations -
Microfluidic Reproduction of Dynamic Bioreactor Environment Based on Computational Lifelines2022 Frontiers in Chemical Engineering article Engineering Innovative Microfluidic and Catalytic Techniques Innovation Open access
Phuong Ho, Sarah Täuber, Birgit Stute, Alexander Grünberger, Eric von Lieres
20citations -
Genetic Cell-Surface Modification for Optimized Foam Fractionation2020 Frontiers in Bioengineering and Biotechnology article Environmental Science Microbial bioremediation and biosurfactants Open access
Christian C. Blesken, Isabel Bator, Christian Eberlein, Hermann J. Heipieper, Till Tiso, Lars M. Blank
37citations
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