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ANP32A represses Wnt signaling across tissues tissues thereby protecting against joint and heart disease2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Silvia Monteagudo, Frederique M. F. Cornelis, X. Wang, Astrid De Roover, Tine Peeters, Jolien Quintiens, +4 more
0citations -
ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Fumin Shi, Jeannine M. Mendrola, Joshua B. Sheetz, Anselm Sommer, Kelsey F. Speer, Jasprina N. Noordermeer, +6 more
2citations -
A Wnt-specific astacin proteinase controls head formation in Hydra2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, +9 more
3citations -
Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signaling2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Vasudha Tandon, Alessandra Fistrovich, Joaquina Nogales, Febe Ferro, Samantha Rokey, Carly R. Cabel, +25 more
0citations -
Wnt-dependent spatiotemporal reprogramming of bone marrow niches drives fibrosis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Bella Banjanin, James Shiniti Nagai, YeVin Mun, Stijn N. R. Fuchs, Inge Snoeren, Joachim Boers, +26 more
1citations -
Modulation of host signalling pathways reveal a major role for Wnt signalling in the maturation of Plasmodium falciparum liver schizonts2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Malaria Research and Control Open access
Abhishek Kanyal, Geert‐Jan van Gemert, Haoyu Wu, Alex van der Starre, Johannes H.W. de Wilt, Teun Bousema, +3 more
0citations -
The implication of TET1, miR-200 and miR-494 expression with tumor formation in colorectal cancer: through targeting WNT signaling2024 Research Square preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Raziye Tajali, Neda Zali, Fatemeh Naderi Noukabadi, Morteza Valinezhad, Farnaz Ghasemian, Makan Cheraghpour, +2 more
0citations -
Lrig1 and Wnt dependent niches dictate segregation of resident immune cells and melanocytes in murine tail epidermis2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology melanin and skin pigmentation Open access
Susanne C. Baess, Ann-Kathrin Burkhart, Sabrina Cappello, Annika Graband, Kristin Seré, Martin Zenke, +2 more
0citations -
Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signalling and clinical traits2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Anagha Krishna, Alison M. Meynert, Martijn J. E. Kelder, Ailith Ewing, Anna Ferrer‐Vaquer, Graeme R. Grimes, +10 more
1citations -
Tankyrase inhibition demonstrates anti-fibrotic effects in preclinical pulmonary fibrosis models2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Shoshy Alam Brinch, Ida Johnsen, Lena Willmer, Ole Vidhammer Bjørnstad, Teresa Lucifora, Karl Martin Forbord, +20 more
0citations -
Dissecting human fetal cardiac repair using cardioids2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Lavinia Ceci Ginistrelli, Tobias Ilmer, Lena Plank, Maria Novatchkova, Abhijeet Krishna, Enikő Lázár, +7 more
0citations -
Extraembryonic endoderm cells induce neuroepithelial tissue in gastruloids2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Noémie M. L. P. Bérenger-Currias, Maria Mircea, Esmée Adegeest, Patrick R. van den Berg, Marleen Feliksik, Mazène Hochane, +3 more
22citations -
Genetic variants for head size share genes and pathways with cancer2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Maria J. Knol, Raymond A. Poot, Tavia E. Evans, Claudia Liliana Satizábal, Aniket Mishra, Sandra Van der Auwera, +90 more
7citations -
Polyploid cardiomyocytes define disease-specific transcriptional states in the mammalian heart2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Paul Kießling, Mehdi Joodaki, Daryna Pikulska, Emilia Scheidereit, Giulia Cesaro, Mayra Ruiz, +52 more
5citations -
Epithelia are multiscale active liquid crystals2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Josep-Maria Armengol-Collado, Livio Nicola Carenza, Julia Eckert, Dimitrios Krommydas, Luca Giomi
3citations -
Binucleated human hepatocytes arise through loss of membrane anchorage to the midbody during endomitosis2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microtubule and mitosis dynamics Open access
Gabriella Darmasaputra, Susana M. Chuva de Sousa Lopes, Hans C. Clevers, Matilde Galli
2citations -
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, +16 more
1citations -
Microbial Invasion and Immunosuppression Drives Adenoma Progression in Early Colorectal Cancer Development2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Wei Liang, Lisa Falk, Daniele Lucarelli, Philipp Putze, Amira Metwaly, Yiran Zheng, +13 more
0citations -
An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCC2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Renal cell carcinoma treatment Open access
Maroussia M. P. Ganpat, Francisco Morales-Rodriguez, Nhung TT Pham, Philip Lijnzaad, Terezinha Maria de Souza, Sepide Derakshan, +10 more
0citations -
Germline genetic contribution to the immune landscape of cancer2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Rosalyn W. Sayaman, Mohamad Saad, Vésteinn Thórsson, Wouter Hendrickx, Jessica P Roelands, Younes Mokrab, +18 more
21citations -
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Hannah Voß, Shweta Godbole, Simon Schlumbohm, Yannis Schumann, Martin Mynarek, Stefan Rutkowski, +14 more
1citations
24 results