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Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders
Andi Shi, Michèle MG Hillege, Carla Offringa, Gang Wu, Tymour Forouzanfar, Willem M.H. Hoogaars, +2 more
1citations -
TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Stephen E. White, Tristin A. Schwartze, Ananya Mukundan, Christina Schoenherr, Shashi Prakash Singh, Maarten van Dinther, +9 more
5citations -
Pro-domain-dependent folding and co-receptor-mediated targeting to optimize an antagonistic TGF-β monomer for gene-based delivery2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Łukasz Wieteska, Cynthia S. Hinck, Ananya Mukundan, Troy C. Krzysiak, Maarten van Dinther, Thibault Vantieghem, +4 more
0citations -
The interplay of TGF-β1 and cholesterol orchestrating hepatocyte cell fate, EMT, and signals for HSC activation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, +11 more
1citations -
SMAD2: Regulatory junction of TGF-β and antigen signaling in mast cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Gina Bronneberg, Steffen K. Meurer, Marlies Kauffmann, Chao‐Chung Kuo, Christian Liedtke, Ralf Weiskirchen, +1 more
1citations -
Dissection of N -, O - and glycosphingolipid glycosylation changes in PaTu-S pancreatic adenocarcinoma cells upon TGF-β challenge2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Jing Zhang, Zejian Zhang, Stephanie Holst, Constantin Blöchl, Katarina Madunić, Manfred Wuhrer, +2 more
0citations -
Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Steven Vermeulen, Nadia J. T. Roumans, Floris Honig, Aurélie Carlier, Dennie G.A.J. Hebels, Aysegul Dede Eren, +3 more
0citations -
Cholesterol modulates type I-type II TGF-β receptor complexes and alters the balance between Smad and Akt signaling in hepatocytes2023 Research Square preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Roohi Chaudhary, Laureen S. Goodman, Sai Wang, Anastasia Asimakopoulo, Ralf Weiskirchen, Steven Dooley, +2 more
0citations -
Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Chen‐Yi Liao, Jasmijn H.M. Hundscheid, Justin Crawford, Peter ten Dijke, Beatrice Coorneaert, Erik H.J. Danen
0citations -
Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Robin J. G. Hartman, Marten A. Siemelink, Saskia Haitjema, Koen F. Dekkers, Lotte Slenders, Arjan Boltjes, +8 more
3citations -
TGFβ signaling in cancer-associated fibroblasts drives a hepatic gp130-dependent pro-metastatic inflammatory program in CMS4 colorectal cancer subtype2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Tom J. Harryvan, Subinuer Abudukelimu, Imke Stouten, EJ van der Wel, Kristiaan Lenos, OJ Sansom, +1 more
0citations -
Modelling phenotypic plasticity in cancer invasion and metastasis: from microscopic interactions to macroscopic dynamics2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Mathematics Mathematical Biology Tumor Growth Open access
Dimitrios Katsaounis, Mark A. J. Chaplain, Nikolaos Sfakianakis
0citations -
Melatonin nanoparticles inhibit mutant hematopoiesis & restore bone marrow architecture in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Siddharth Gupta, Alessandro Motta, Sara Elsafy, Shiva Khorshid, Alessia Nucci, Vishrutha Sampath, +21 more
0citations -
Capture of Post-Pluripotency Human Neuromesodermal and Neural Tube Axial Stem Cell States2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Dolunay Kelle, Enes Ugur, Ejona Rusha, Dmitry Shaposhnikov, Alessandra Livigni, Sandra Horschitz, +16 more
4citations -
EMT-dependent cell-matrix interactions are linked to unjamming transitions in cancer spheroid invasion2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Anouk van der Net, Ankur Bordoloi, Iain Muntz, Peter ten Dijke, Pouyan E. Boukany, Gijsje Hendrika Koenderink
3citations -
Single cell trajectory analysis of human pluripotent stem cells differentiating towards lung and hepatocyte progenitors2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Chaido Ori, Meshal Ansari, Ilias Angelidis, Fabian Joachim Theis, Herbert B. Schiller, Micha Drukker
2citations -
The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Mohamed H. Elsafi Mabrouk, Roman Goetzke, Giulio Abagnale, Burcu Yesilyurt, Lucia Salz, Kira Zeevaert, +8 more
1citations -
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, +16 more
1citations -
Ageing of the Upper Airway Epithelial Niche Limits Tissue-Resident T Cell Immunity2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Wesley Huisman, Lisa A. King, Youvika Singh, Alicia C. de Kroon, Rosanne A. M. Steenbergen, Iris van der Valk, +19 more
0citations -
Tankyrase inhibition demonstrates anti-fibrotic effects in preclinical pulmonary fibrosis models2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Shoshy Alam Brinch, Ida Johnsen, Lena Willmer, Ole Vidhammer Bjørnstad, Teresa Lucifora, Karl Martin Forbord, +20 more
0citations -
Prrx1b directs pro-regenerative fibroblasts during zebrafish heart regeneration2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Dennis E. M. de Bakker, Esther Dronkers, Mara Bouwman, Aryan Vink, Marie‐José Goumans, Anke M. Smits, +1 more
0citations -
Deep Visual Proteomics links vascular smooth muscle cell phenotypes to atherosclerotic plaque stability2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Elena Kratz, Ankit Sinha, Trusha Adeshara, Valentina Paloschi, Nadja Sachs, Jessica Pauli, +10 more
0citations -
Comparative human embryo-mapping reveals neural bias of neuromesodermal progenitors in stem cell axial elongation models2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Yuting Wang, Rafaella Buzatu, Cecile Herbermann, Micha Drukker, Christian J. Schröter
0citations -
Methylation-Guided Stratification of Colorectal Cancer Reveals Immune Subtypes with Distinct Clinical Outcomes2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation
Eiman I. Ahmed, Raghvendra Mall, Christophe Michel Raynaud, Heba Saadeh, Shimaa Sherif, Rania Alanany, +4 more
0citations