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Switch Control Inhibition of KIT and PDGFRA in Patients With Advanced Gastrointestinal Stromal Tumor: A Phase I Study of Ripretinib2020 Journal of Clinical Oncology article Medicine Gastrointestinal Tumor Research and Treatment Open access
Filip Jankú, Albiruni R. Abdul Razak, Ping Chi, Michael Charles Heinrich, Margaret von Mehren, Robin L. Jones, +10 more
91citations -
Atherosclerotic plaque fibroblasts derive from adventitial and medial Pdgfra -lineage-positive cells and predominantly maintain fibroblast identity2026 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Guanliang Li, S. Asselberghs, Baixue Yu, Cong Feng, Paul‐Lennard Mendez, Dimitri Kasakovski, +22 more
0citations -
Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol2023 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Kim van Kuijk, Ian R McCracken, Renée J. H. A. Tillie, S. Asselberghs, Dlzar Ali Kheder, Stan Muitjens, +22 more
48citations -
Oligogenic analysis across broad phenotypes of 46,XY differences in sex development associated with NR5A1/SF-1 variants: findings from the international SF1next study2025 EBioMedicine article Biochemistry, Genetics and Molecular Biology Sexual Differentiation and Disorders Open access
Chrysanthi Kouri, Idoia Martinez de la Piscina, Rawda Naamneh Elzenaty, Grit Sommer, Kay‐Sara Sauter, Christa E. Flück, +66 more
9citations -
A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex2025 eLife article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Cecilia Hes, Abigail J. Tomlinson, Lieke Michielsen, Hunter J Murdoch, Maia V. Kokoeva, Paul V. Sabatini
1citations -
Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous KIT/PDGFRA Mutations in the Phase III INVICTUS Study2021 Clinical Cancer Research article Medicine Gastrointestinal Tumor Research and Treatment Open access
Sebastian Bauer, Michael Charles Heinrich, Suzanne George, John Raymond Zalcberg, César Serrano, Hans A. J. Gelderblom, +11 more
46citations -
1623MO Ripretinib intra-patient dose escalation (IPDE) following disease progression provides clinically meaningful progression-free survival (PFS) in gastrointestinal stromal tumor (GIST) in phase I study
Filip Jankú, Ping Chi, Michael Charles Heinrich, Margaret von Mehren, Robin L. Jones, Kristen N. Ganjoo, +9 more
4citations -
1622MO Clinical benefit with ripretinib as ≥4th line treatment in patients with advanced gastrointestinal stromal tumors (GIST): Update from the phase III INVICTUS study
John Raymond Zalcberg, Michael Charles Heinrich, Suzanne George, Sebastian Bauer, Hans A. J. Gelderblom, Patrick Schöffski, +12 more
1citations -
Epithelial PDGF-C Contributes to Crescentic Glomerulonephritis and FSGS in Part via Activation of Parietal Epithelial Cells2026 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies
Ina Verena Martin, Yingying Gao, Dickson W.L. Wong, Roman David Bülow, Mirna Barsoum, Lisa Nguyen, +14 more
0citations -
Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS): a double-blind, randomised, placebo-controlled, phase 3 trial2020 The Lancet Oncology article Medicine Gastrointestinal Tumor Research and Treatment Open access cited by 48 patents
Jean‐Yves Blay, César Serrano, Michael Charles Heinrich, John Raymond Zalcberg, Sebastian Bauer, Hans A. J. Gelderblom, +11 more
430citations -
Patient-reported outcomes in individuals with advanced gastrointestinal stromal tumor treated with ripretinib in the fourth-line setting: analysis from the phase 3 INVICTUS trial
Patrick Schöffski, Suzanne George, Michael Charles Heinrich, John Raymond Zalcberg, Sebastian Bauer, Hans A. J. Gelderblom, +12 more
10citations -
A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex2025 eLife article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Cecilia Hes, Abigail J. Tomlinson, Lieke Michielsen, Hunter J Murdoch, Maia V. Kokoeva, Paul V. Sabatini
0citations
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