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A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology IL-33, ST2, and ILC Pathways Open access
Graham A. Heieis, Bart Everts, Craig W. Roberts, Rick M. Maizels, Georgia Perona‐Wright
1citations -
EOMES and IL-10 regulate anti-tumor activity of PD-1 + CD4 + T-cells in B-cell Non-Hodgkin lymphoma2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Philipp M. Roessner, Laura Llaó Cid, Ekaterina Lupar, Tobias Roider, Marie Bordas, Christoph Schifflers, +10 more
4citations -
Immunophenotyping of T cells Combined with Vβ antibodies identifies long lasting CMV related T cell Expansions with a consistent TIGIT and PD-1 phenotype2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology
Monique M. van Ostaijen-ten Dam, Marco W. Schilham, Arjan C. Lankester, Janine E. Melsen
0citations -
CRISPR activation screening identifies VGLL3 and GATA2 as transcriptional regulators of PD-L12021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Ruud H. M. Wijdeven, Birol Cabukusta, Xueer Qiu, Daniel Borràs, Yun Liang, Jacques Neefjes
0citations -
OX40 agonism enhances efficacy of PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Guillaume Beyrend, Tetje Cornelia van der Sluis, Esmé T.I. van der Gracht, Tamim Abdelaal, Simon P. Jochems, Robert A. Belderbos, +16 more
0citations -
TIGIT drives the immunosuppressive environment by downregulation of metalloproteinases MMP2 and MMP14 in perihilar cholangiocarcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Lara Rosaline Heij, Konrad Reichel, Willem de Koning, Jan Bednarsch, Xiuxiang Tan, Julia Campello Deierl, +13 more
0citations -
Tumour-derived factors prime microglia for immune checkpoint-mediated T-cell regulation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Luca D Schreurs, Jessica Barz, Trong-Hieu Nguyen, Jule Schmedding, Liudmila Lobastova, Patrick Hoelker, +9 more
0citations -
Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Colorectal Cancer Treatments and Studies Open access
Christina Plattner, Giorgia Lamberti, Peter Blattmann, Alexander Kirchmair, Dietmar Rieder, Zuzana Loncová, +23 more
0citations -
Gut microbiota mediates trafficking of intestinal T cells to the brain to exacerbate neuroinflammation after ischemic stroke2025 Research Square preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Zhuang Li, Nannan Guo, Xiangyu Zuo, Jinlian Shao, Fabing Zhang, Yu Xiao, +19 more
0citations -
γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Natasja L. De Vries, Joris van de Haar, Vivien Veninga, Myriam Chalabi, Marieke E. Ijsselsteijn, Manon van der Ploeg, +8 more
3citations -
Mass cytometry data integration methods reveal rural-urban gradient of immune profiles across geography2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics
Koen A. Stam, Jeremia Jackson Pyuza, Mikhael D. Manurung, Dicky L. Tahapary, Taniawati Supali, Marloes M.A.R. van Dorst, +5 more
1citations -
PD1+ T-cells correlate with Nerve Fiber Density as a prognostic biomarker in patients with resected perihilar cholangiocarcinoma2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Xiuxiang Tan, Mika Rosin, Simone Appinger, Jan Bednarsch, Dong Liu, Georg J. Wiltberger, +19 more
1citations -
The landscape of tertiary lymphoid structures in endometrial cancer revealed through harmonized multi-level transcriptomics2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Marta Requesens, Koen Brummel, Arkajyoti Bhattacharya, Feija Somefun, Nienke van Rooij, Annechien Plat, +10 more
0citations -
Inflammatory signature and restriction of adaptive immunity are associated with unfavorable outcomes on immune checkpoint blockade in patients with advanced head and neck squamous cell carcinoma
Lisa Paschold, Christoph Schultheiß, Paul Schmidt-Barbo, Konrad Friedrich Klinghammer, Dennis Hahn, Mareike Tometten, +8 more
0citations
20 results