Papers matching “PARP inhibitor sensitivity” 21
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STING loss attenuates ISG expression without affecting PARP inhibitor sensitivity in Brca1+/− Jak2V617F MPN2026 Scientific Reports article Immunology and Microbiology interferon and immune responses Open access
Mirjam Hanako Sarholz, María Jimena Rodriguez, Tomasz Skórski, Steffen Koschmieder, Julian Baumeister
0citations -
Abstract P056: Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Molecular Cancer Therapeutics conference-abstract Medicine PARP inhibition in cancer therapy cited by 1 patent
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +42 more
3citations -
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Nature Communications article Medicine PARP inhibition in cancer therapy Open access cited by 18 patents
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +53 more
370citations -
S6K1 and S6K2 regulate homologous recombination DNA repair through control of BRCA1 protein stability2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms
Mariana Marcela Góis, Lais Bonafe, L O Silva, Mariana Camargo Silva Mancini, Rosalie A. Kampen, Isadora Carolina Betim Pavan, +4 more
0citations -
Does PARP Inhibition Sensitize Chondrosarcoma Cell Lines to Chemotherapy or Radiotherapy? Results From a Three-dimensional Spheroid Cell Model2022 Clinical Orthopaedics and Related Research article Medicine Bone Tumor Diagnosis and Treatments Open access
Ieva Palubeckaitė, Sanne Venneker, Brendy E.W.M. van den Akker, Inge H. Briaire‐de Bruijn, Judith V.M.G. Bovée
12citations -
ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination2022 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Seong-Ok Lee, Hsin‐Ru Chan, Martijn S. Luijsterburg, Justin W. C. Leung, Kyle M. Miller
39citations -
Evaluation of BRCA1/2 testing rates in epithelial ovarian cancer patients: lessons learned from real-world clinical data2025 Familial Cancer article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Lieke Lanjouw, Claire J.H. Kramer, Arja ter Elst, Geertruida H. de Bock, Katja N. Gaarenstroom, Refika Yigit, +10 more
2citations -
Site-saturation functional screens identify PALB2 missense variants associated with increased breast cancer risk2026 Nature Communications article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Rick A.C.M. Boonen, Sabine Knaup, Roberta Menafra, Merel E. Braspenning, Magdalena B. Rother, Petra Kleiblová, +55 more
1citations -
Performance of a RAD51-based functional HRD test on paraffin-embedded breast cancer tissue2023 Breast Cancer Research and Treatment article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Lise M. van Wijk, Sylvia Vermeulen, Natalja T. ter Haar, Claire J.H. Kramer, Diantha Terlouw, Harry Vrieling, +2 more
10citations -
RAD51 as a functional biomarker for homologous recombination deficiency in cancer: a promising addition to the HRD toolbox?2021 Expert Review of Molecular Diagnostics article Medicine PARP inhibition in cancer therapy Open access cited by 1 patent
Lise M. van Wijk, Andreea B. Nilas, Harry Vrieling, Maaike P.G. Vreeswijk
37citations -
Advancements in PARP1 Targeted Nuclear Imaging and Theranostic Probes2020 Journal of Clinical Medicine article Medicine Radiopharmaceutical Chemistry and Applications Open access
Ramya Ambur Sankaranarayanan, Susanne Kossatz, Wolfgang Weber, Mohsen Beheshti, Agnieszka Morgenroth, Felix Manuel Mottaghy
42citations -
Poly-(ADP-ribose) serves as a scaffold for the methyltransferase METTL3/14 complex in the DNA damage response2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Claudia Gonzalez-Leal, Jin Cai, Bram A F J de Groot, Andreas Wegerer, Julia Preißer, Martijn S. Luijsterburg, +1 more
6citations -
Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators2024 Molecular & Cellular Proteomics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Rathan S Jadav, Florian Weiland, Sylvie M. Noordermeer, Thomas D. Carroll, Yuandi Gao, Jianming Wang, +11 more
8citations
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