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Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms2023 International Journal of Molecular Sciences article Medicine PARP inhibition in cancer therapy Open access
Max Bermes, María Jimena Rodriguez, Marcelo A. S. Toledo, Sabrina Ernst, Gerhard Müller‐Newen, Tim H. Brümmendorf, +3 more
7citations -
Does PARP Inhibition Sensitize Chondrosarcoma Cell Lines to Chemotherapy or Radiotherapy? Results From a Three-dimensional Spheroid Cell Model2022 Clinical Orthopaedics and Related Research article Medicine Bone Tumor Diagnosis and Treatments Open access
Ieva Palubeckaitė, Sanne Venneker, Brendy E.W.M. van den Akker, Inge H. Briaire‐de Bruijn, Judith V.M.G. Bovée
12citations -
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes2023 Journal of Medicinal Chemistry article Medicine PARP inhibition in cancer therapy Open access cited by 1 patent
Sudarshan Murthy, Maria Giulia Nizi, Mirko M. Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E. Lippok, +11 more
30citations -
[1,2,4]Triazolo[3,4- b ]benzothiazole scaffold as versatile nicotinamide mimic allowing nanomolar inhibition of different PARP enzymes2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine PARP inhibition in cancer therapy Open access
Sudarshan Murthy, Maria Giulia Nizi, Mirko M. Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E. Lippok, +11 more
0citations -
PARP and PD-1/PD-L1 checkpoint inhibition in recurrent or metastatic endometrial cancer2020 Critical Reviews in Oncology/Hematology article Medicine Endometrial and Cervical Cancer Treatments Open access cited by 1 patent
Cathalijne Post, Anneke M. Westermann, Tjalling Bosse, Carien L. Creutzberg, Judith R. Kroep
61citations -
Exploiting the synergistic effect of PARP inhibition with cisplatin and hyperthermia during interval cytoreductive surgery and HIPEC in ovarian cancer: the PROOV study - A phase I/II clinical trial2026 International Journal of Gynecological Cancer article Medicine Intraperitoneal and Appendiceal Malignancies
Leah Frenkel, Madelief Schreuder Goedheijt, Carolina Velázquez, Marta López‐Yurda, Daniela Annibali, Frans L. Opdam, +7 more
0citations -
Abstract P056: Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Molecular Cancer Therapeutics conference-abstract Medicine PARP inhibition in cancer therapy cited by 1 patent
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +42 more
3citations -
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Nature Communications article Medicine PARP inhibition in cancer therapy Open access cited by 18 patents
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +53 more
370citations -
Optimization of 2,3-dihydrophthalazine-1,4-dione PARP inhibitor scaffold for nanomolar potency and specificity towards human PARP102025 European Journal of Medicinal Chemistry article Medicine PARP inhibition in cancer therapy Open access
Juho Alaviuhkola, Maria Giulia Nizi, Chiara Vagaggini, Chiara Sarnari, Barbara E. Lippok, Mirko M. Maksimainen, +8 more
1citations -
PARP-inhibitor response evaluation in recurrent epithelial ovarian cancer using circulating tumor DNA and functional HRD testing2026 International Journal of Gynecological Cancer article Medicine PARP inhibition in cancer therapy Open access
Merel Vegter, Lise M. van Wijk, CJH Kramer, M. Jalving, T. Bosse, Dik C. van Gent, +9 more
0citations -
469 Survey on the usage of PARP-inhibitor therapy in Germany – a national NOGGO/JAGO-AGO intergroup study2021 International Journal of Gynecological Cancer article Medicine PARP inhibition in cancer therapy Open access
Bich Doan Nguyen-Sträuli, P Meyer-Wilmes, Joanna Baum, A Kreklau, Christina Buschmann, S Boz, +6 more
0citations -
Gene Expression And Patient-Reported Outcomes Reveal Links Between Circadian Rhythm Disruption And PARP Inhibitor Toxicity In Ovarian Cancer Patients2025 International Journal of Gynecological Cancer article Medicine PARP inhibition in cancer therapy Open access
Deeksha Malhan, Janina Hesse, Nina Nelson, Jessica Nguyen, Ouda Aboumanify, Josefin Garmshausen, +12 more
0citations -
Correction: Sankaranarayanan et al. Auger Emitter Conjugated PARP Inhibitor for Therapy in Triple Negative Breast Cancers: A Comparative In-Vitro Study. Cancers 2022, 14, 230
Ramya Ambur Sankaranarayanan, Jennifer Peil, Andreas Theodor Josef Vogg, Carsten Bolm, Steven Terhorst, Arno Claßen, +4 more
0citations