Papers matching “Mendelian randomization” 113
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Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome2021 Nature Communications article Medicine Parkinson's Disease Mechanisms and Treatments Open access cited by 1 patent
Catherine S. Storm, Demis A. Kia, Mona Mohammad Almramhi, Sara Bandrés Ciga, Chris Finan, Alastair John Noyce, +94 more
209citations -
Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study2023 Headache The Journal of Head and Face Pain article Medicine Migraine and Headache Studies Open access
Nike Zoe Welander, Gull Rukh, Mathias Rask‐Andersen, Aster V. E. Harder, Arn M. J. M. van den Maagdenberg, Helgi B. Schiöth, +1 more
13citations -
Association Between Low Sex Hormone–Binding Globulin and Increased Risk of Type 2 Diabetes Is Mediated by Increased Visceral and Liver Fat: Results From Observational and Mendelian Randomization Analyses
Theresa A Stangl, Chantal Maria Wiepjes, Roelof A. J. Smit, Astrid van Hylckama Vlieg, Hildo J. Lamb, Jeroen H. P. M. van der Velde, +7 more
17citations -
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, Bastiaan T. Heijmans, Peter A.C. ’t Hoen, Joyce B. J. van Meurs, +6 more
61citations -
The association between mitochondrial DNA abundance and stroke: A combination of multivariable-adjusted survival and Mendelian randomization analyses2022 Atherosclerosis article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Leon G. Martens, Jiao Min Luo, Marieke J.H. Wermer, Ko Willems van Dijk, Sara Hägg, Felix Graßmann, +2 more
15citations -
Exploring Sex Differences in Pain Manifestation of Coronary Artery Disease through Mendelian Randomization2024 Journal of Cardiovascular Development and Disease article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Ruben Methorst, Monique R.M. Jongbloed, Raymond Noordam, Marco C. DeRuiter
1citations -
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank2024 Mitochondrion article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Jiao Min Luo, Saskia le Cessie, Ko Willems van Dijk, Sara Hägg, Felix Graßmann, Diana van Heemst, +1 more
0citations -
The association between leptin and subclinical cardiovascular disease explained by body fat: Observational and Mendelian randomization analyses2023 Nutrition Metabolism and Cardiovascular Diseases article Medicine Adipokines, Inflammation, and Metabolic Diseases Open access
Tim Christen, Renée de Mutsert, Roelof A. J. Smit, Ko Willems van Dijk, Hildo J. Lamb, Frits Richard Rosendaal, +2 more
3citations -
Higher thyroid stimulating hormone leads to cardiovascular disease and an unfavorable lipid profile: EVidence from multi-cohort Mendelian randomization and metabolomic profiling
Nicolien A van Vliet, Maxime M. Bos, Carisha S. Thesing, Layal Chaker, Maik Pietzner, Evelyn Houtman, +36 more
1citations -
Classical risk factors for primary coronary artery disease from an ageing perspective through Mendelian randomization2021 Atherosclerosis article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology
Samara M. A. Jansen, Bas Huiskens, Stella Trompet, J. Wouter Jukema, Simon P. Mooijaart, Ko Willems van Dijk, +2 more
0citations -
No evidence linking sleep traits with white blood cell counts: Multivariable‐adjusted and Mendelian randomization analyses2024 European Journal of Clinical Investigation article Psychology Sleep and related disorders Open access
Raymond Noordam, Linjun Ao, Jasmijn F. Stroo, Ko Willems van Dijk, Diana van Heemst
2citations -
The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study2020 International Journal of Epidemiology article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Inge Verkouter, Renée de Mutsert, Roelof A. J. Smit, Stella Trompet, Frits Richard Rosendaal, Diana van Heemst, +2 more
14citations -
Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study2021 Journal of the American Society of Nephrology article Medicine Chronic Kidney Disease and Diabetes Open access
Pamela R. Matías‐García, Rory Wilson, Qi Guo, Shaza B. Zaghlool, James Eales, Xiaoguang Xu, +31 more
45citations -
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling
Nicolien A van Vliet, Maxime M. Bos, Carisha S. Thesing, Layal Chaker, Maik Pietzner, Evelyn Houtman, +38 more
26citations -
Bidirectional Mendelian Randomization Highlights Causal Relationships Between Circulating INHBC and Multiple Cardiometabolic Diseases and Traits2024 Diabetes article Medicine Adipokines, Inflammation, and Metabolic Diseases Open access cited by 2 patents
Nellie Y. Loh, Daniel B. Rosoff, Rebecca Claire Richmond, Raymond Noordam, George Davey Smith, David Ray, +3 more
11citations -
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study2021 Journal of Crohn s and Colitis article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Jiao Min Luo, Zhongwei Xu, Raymond Noordam, Diana van Heemst, Ruifang Li‐Gao
158citations