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#2559 High-resolution nanoliquid chromatography-mass spectrometry of circulating IgA1 glycosylation provides novel insight in the pathogenesis of IgA nephropathy2025 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access
Anastasia Tzasta, Tomas G.J.M. Post, Anna Wasynczuk, Steinar Gijze, Ilse M. Rood, Elmar Pieterse, +6 more
0citations -
Genome-Wide Association Study (GWAS) of Serum Galactose-Deficient IgA1 Uncovers Shared Genetic Determinants with IgAN2025 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies
Lili Liu, Atlas Khan, Colin Reily, Stacy D. Hall, Todd J. Green, Bruce A. Julian, +12 more
1citations -
Role of Systemic Glucocorticoids in Reducing IgA and Galactose-Deficient IgA1 Levels in IgA Nephropathy2025 Clinical Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies Open access
Jincan Zan, Jingyi Li, Muh Geot Wong, Dana Kim, Sufang Shi, Helen Monaghan, +3 more
7citations -
#2859 ORIGIN 2b: changes in Gd-IgA1 and eGFR after discontinuation of atacicept treatment in IgA nephropathy2025 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access
Jonathan Barratt, Sean J. Barbour, Necmi Eren, Jürgen Floege, Vivekanand Jha, Sung Gyun Kim, +5 more
2citations -
Atacicept 150 mg Reduces Serum Gd-IgA1, a Biomarker Associated with Long-Term Outcomes in IgA Nephropathy (IgAN): 36W Results from the Ph2b ORIGIN Study2023 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies
Jonathan Barratt, Bart Maes, Celia J. F. Lin, Xuelian Wei, Sean J. Barbour, Richard K. S. Phoon, +5 more
2citations -
AB0077 IN RHEUMATOID ARTHRITIS PATIENTS, TOTAL IgA1 AND IgA2 LEVELS ARE ELEVATED: IMPLICATIONS FOR THE MUCOSAL ORIGIN HYPOTHESIS2022 Annals of the Rheumatic Diseases conference-abstract Medicine Rheumatoid Arthritis Research and Therapies Open access
Veerle F. A. M. Derksen, Cornelia F Allaart, A. van der Helm-van Mil, Tom W. J. Huizinga, René E. M. Toes, Diane van der Woude
0citations -
Atacicept reduces hematuria and serum gd-iga1, both associated with long-term renal outcomes in iga nephropathy: 36-week results from the phase 2b origin study2024 RWTH Publications (RWTH Aachen) article Medicine Renal Diseases and Glomerulopathies Open access
Jonathan Barratt, Bart Maes, Celia Lin, Xuelian Wei, Sean Barbour, Richard Phoon, +5 more
0citations -
O- and N-Glycosylation of Serum Immunoglobulin A is Associated with IgA Nephropathy and Glomerular Function2021 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies Open access cited by 3 patents
Viktoria Dotz, Alessia Visconti, Hannah J. Lomax-Browne, Florent Clerc, Agnes L. Hipgrave Ederveen, Nicholas Medjeral‐Thomas, +4 more
98citations -
#3848 ORIGIN TRIAL: 24-WK PRIMARY ANALYSIS OF A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PH2B STUDY OF ATACICEPT IN PATIENTS WITH IGAN2023 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access
Richard A. Lafayette, Bart Maes, Celia J. F. Lin, Sean J. Barbour, Richard K. S. Phoon, Sung Gyun Kim, +4 more
14citations -
IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression2025 Cell Communication and Signaling article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
David Falck, Maria V Sokolova, Carolien A. M. Koeleman, Vanessa Irumva, Philipp Kirchner, Sebastian R. Schulz, +8 more
6citations -
IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
David Falck, Maria V Sokolova, Carolien A. M. Koeleman, Vanessa Irumva, Philipp Kirchner, Sebastian R. Schulz, +8 more
0citations -
IgA subclasses have different effector functions associated with distinct glycosylation profiles2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access cited by 4 patents
Ulrike Steffen, Carolien A. M. Koeleman, Maria V Sokolova, Holger Bang, Arnd Kleyer, Jürgen Rech, +16 more
277citations -
Long-Term Results from an Open-Label Extension Study of Atacicept for the Treatment of IgA Nephropathy2024 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies Open access
Jonathan Barratt, Sean J. Barbour, Kerry Cooper, Xuelian Wei, Necmi Eren, Jürgen Floege, +7 more
61citations -
Long-Term Results from the ORIGIN Phase 2b Study of Atacicept for the Treatment of IgA Nephropathy (IgAN)2024 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies
Jonathan Barratt, Sean J. Barbour, Kerry Cooper, Xuelian Wei, Necmi Eren, Jürgen Floege, +7 more
3citations -
#3251 Nefecon provides kidney benefit irrespective of time since diagnosis in patients with IgAN: a subanalysis of the NefIgArd study2025 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access
Richard A. Lafayette, Jonathan Barratt, Heather N. Reich, Jens Halkjaer Kristensen, Russell F Jones, Jürgen Floege, +4 more
0citations -
#2651 Sustainability and depth of UPCR reduction in patients with primary IgAN treated with nefecon: a secondary analysis of the Phase 3 NefIgArd trial2025 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access
Jonathan Barratt, Heather N. Reich, Jens Halkjaer Kristensen, Russell F Jones, Jürgen Floege, Vladimı́r Tesař, +4 more
0citations