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Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis2021 Mucosal Immunology article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Maria E. Joosse, Fabienne Charbit‐Henrion, Remy Boisgard, Rolien C. Raatgeep, Dicky J. Lindenbergh-Kortleve, Lea M. M. Costes, +11 more
33citations -
1009 Co-stimulatory signals via CD28 and CD27 collaborate to regulate activation and IL-2 production of CD8+ T Cells through distinct mechanisms2023 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology T-cell and B-cell Immunology Open access
Felix M. Behr, Anke Redeker, Suzanne P. M. Welten, Ward Vleeshouwers, Reza Nadafi, Elham Beyranvand Nejad, +3 more
0citations -
IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participants2026 Nature Communications article Immunology and Microbiology T-cell and B-cell Immunology Open access
Igor Radanović, Michael DiDonato, Anouk C. Meijs, Yaiza Diaz De Durana, Andrea Kießling, Thierry Flandre, +31 more
0citations -
IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p2024 Journal of Translational Medicine article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Ehsan Gharib, Leili Rejali, Moein Piroozkhah, Elham Zonoobi, Parinaz Nasri Nasrabadi, Zahra Arabsorkhi, +6 more
13citations -
Trsp is required by regulatory T cells to prevent lethal autoimmunity in mice2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Justin Jacobse, Jennifer M. Pilat, Aaron Kwag, Zaryab Aziz, Channing Chi, M. Diana Neely, +13 more
0citations -
CD27 costimulation supports metabolic fitness of CD4+ T cells by enhancing de novo nucleotide and protein synthesis2025 The Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Thi Tran Ngoc Minh, Lotte J. Verleng, Ellen Schrama, Julia Busselaar, Mo D. Staal, Evert de Vries, +5 more
6citations -
Point-of-care-ready nanoscale ISFET arrays for sub-picomolar detection of cytokines in cell cultures2020 Analytical and Bioanalytical Chemistry article Chemical Engineering Analytical Chemistry and Sensors Open access
Dipti Rani, Yogesh Singh, Madhuri S. Salker, Xuan Thang Vu, Sven Ingebrandt, Vivek Pachauri
32citations -
P133 In vitro pharmacological profile of GLPG3667 suggests differentiation from the TYK2 inhibitors deucravacitinib and TAK-279 at their clinical dose regimens2024 Journal of Crohn s and Colitis conference-abstract Medicine Cytokine Signaling Pathways and Interactions Open access
Willem Hettema, Patrick Nolain, Isabelle Parent, Roland Blanqué, Laetitia Furio, Lucia Angella, +1 more
1citations -
Plasma Levels of Bile Acids Are Related to Cardiometabolic Risk Factors in Young Adults2021 The Journal of Clinical Endocrinology & Metabolism article Medicine Cholesterol and Lipid Metabolism Open access
Francisco J. Osuna‐Prieto, José Rubio‐López, Xinyu Di, Wei Yang, Isabelle Köhler, Patrick C.N. Rensen, +2 more
21citations
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