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Cryo-EM structures reveal how ATP and DNA binding in MutS coordinate the sequential steps of DNA mismatch repair2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Alessandro Borsellini, Vladislav Kunetsky, Peter Friedhoff, Meindert Hugo Lamers
1citations -
Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair2022 Nature Structural & Molecular Biology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Alessandro Borsellini, Vladislav Kunetsky, Peter Friedhoff, Meindert Hugo Lamers
21citations -
The selection process of licensing a DNA mismatch for repair2021 Nature Structural & Molecular Biology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Rafael Fernández-Leiro, Doreth Bhairosing-Kok, Vladislav Kunetsky, Charlie Laffeber, Herrie H. K. Winterwerp, Flora S. Groothuizen, +5 more
42citations -
DNA mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines2024 DNA repair article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Anastasia Tsaalbi‐Shtylik, Cécile Mingard, Michael H. Räz, Rurika Oka, Freek Manders, Ruben van Boxtel, +2 more
8citations -
Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding2023 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Susanne R. Bruekner, Wietske Pieters, Alexander Fish, A. Manuel Liaci, Serge Scheffers, Emily Rayner, +12 more
11citations -
Mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines2023 Zenodo (CERN European Organization for Nuclear Research) article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Anastasia Tsaalbi‐Shtylik, Mingard Cécile, R. Knowles Michael, Oka Rurika, Manders Freek, Van Boxtel Ruben, +2 more
0citations -
28 Prevalence and prognosis of lynch syndrome and sporadic mismatch repair deficiency in the combined PORTEC-1,-2 and -3 endometrial cancer trials2020 International Journal of Gynecological Cancer article Medicine Genetic factors in colorectal cancer Open access
Cathalijne Post, Ellen Stelloo, Vincent T.H.B.M. Smit, Dina Ruano, Carli M.J. Tops, Lisa Vermij, +15 more
2citations -
Assessing pathogenicity of mismatch repair variants of uncertain significance by molecular tumor analysis2024 Experimental and Molecular Pathology article Medicine Genetic factors in colorectal cancer Open access
Noah C. Helderman, Arnoud Boot, Diantha Terlouw, Hans Morreau, Hailiang Mei, Rebecca E. E. Esveldt–van Lange, +10 more
2citations -
γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Natasja L. De Vries, Joris van de Haar, Vivien Veninga, Myriam Chalabi, Marieke E. Ijsselsteijn, Manon van der Ploeg, +8 more
3citations -
Combined prognostic value of post-surgery circulating tumor DNA and tumor-stroma ratio in patients with stage III colon cancer treated with adjuvant chemotherapy.2025 Journal of Clinical Oncology conference-abstract Medicine Colorectal Cancer Surgical Treatments Open access
Ingrid A. Franken, Floor Heilijgers, Marie-Christine Bakker, Carmen Rubio Alarcon, Nerma Crnovrsanin, Margriet Lemmens, +8 more
3citations -
Tandem Substitutions in Somatic Hypermutation2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Julieta Sepúlveda-Yáñez, Diego Álvarez-Saravia, Bas Pilzecker, Pauline A. van Schouwenburg, Mirjam van der Burg, Hendrik Veelken, +3 more
4citations -
Tandem Substitutions in Somatic Hypermutation2021 Blood conference-abstract Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Marvyn T. Koning, Julieta Sepúlveda-Yáñez, Diego Álvarez-Saravia, Bas Pilzecker, Pauline A. van Schouwenburg, Mirjam van der Burg, +3 more
1citations -
Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy2020 Journal of Clinical Oncology article Medicine Endometrial and Cervical Cancer Treatments Open access cited by 1 patent
Alicia León‐Castillo, Stephanie M. de Boer, Melanie E. B. Powell, Linda Mileshkin, Helen J MacKay, Alexandra F. Leary, +16 more
877citations