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The Effects of Mercaptopurine on Pulmonary Vascular Resistance and BMPR2 Expression in Pulmonary Arterial Hypertension2020 American Journal of Respiratory and Critical Care Medicine article Medicine Pulmonary Hypertension Research and Treatments Open access
Liza Botros, Robert Szulcek, Samara M. A. Jansen, Kondababu Kurakula, Marie‐José Goumans, André B. P. Kuilenburg, +4 more
13citations -
Abstract 4363865: Unaffected Carriers of a Pathogenic BMPR2 Variant Exhibit a Distinct Cytokine Signature Associated with Subclinical Changes on Right Ventricular and Pulmonary Vascular Imaging
Clarissa Becher, Carolina Janssen-Telders, Jessie van Wezenbeek, Aida Llucià Valldeperas, JanWillem Duitman, Marie‐José Goumans, +2 more
0citations -
Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP102022 Nature Communications article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Jingxu Guo, Bin Liu, Midory Thorikay, Minmin Yu, Xiaoyan Li, Zhen Tong, +5 more
23citations -
MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension2020 International Journal of Molecular Sciences article Medicine Pulmonary Hypertension Research and Treatments Open access
Maria Catalina Gomez‐Puerto, Xiao‐Qing Sun, Ingrid Schalij, Mar Orriols, Xiaoke Pan, Robert Szulcek, +4 more
7citations -
Interfering in the ALK1 Pathway Results in Macrophage-Driven Outward Remodeling of Murine Vein Grafts2022 Frontiers in Cardiovascular Medicine article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Alwin de Jong, Vincent Q. Sier, Hendrika A. B. Peters, Natalia K. M. Schilder, J. Wouter Jukema, Marie‐José Goumans, +2 more
12citations -
Abstract 10462: Increased Bone Morphogenetic Protein 10 Activity is Associated with Increased Right Atrial Wall Stress and Disease Severity in Pulmonary Hypertension2021 Circulation conference-abstract Medicine Pulmonary Hypertension Research and Treatments cited by 1 patent
Aida Llucià Valldeperas, Jessie van Wezenbeek, Joanne A. Groeneveldt, Gonzalo Sánchez‐Duffhues, Rowan Smal, Xiaoke Pan, +4 more
1citations -
Upcoming expression of ALK1 in HCC determines the switch from tumour-suppressive to tumour-promoting BMP-9 signalling2021 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases
Haristi Gaitantzi, Timo Itzel, A Teufel, Steven Dooley, Lukas J.A.C. Hawinkels, Emrullah Birgin, +2 more
0citations -
Increased bone morphogenetic protein 10 in precapillary pulmonary hypertension patients2024 Cardiovascular Research article Medicine Pulmonary Hypertension Research and Treatments Open access
Aida Llucià Valldeperas, Jessie van Wezenbeek, J.A. Groeneveldt, rowan Smal, Gonzalo Sánchez‐Duffhues, M. Louis Handoko, +8 more
0citations -
Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors2020 Bone article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access cited by 13 patents
Gonzalo Sánchez‐Duffhues, Eleanor Williams, Marie‐José Goumans, Carl‐Henrik Heldin, Peter ten Dijke
118citations -
Selective inhibition of Histone deacetylases reverses vascular remodeling and improves right ventricle function in pulmonary hypertension2024 Cardiovascular Research article Medicine Pulmonary Hypertension Research and Treatments Open access
Kondababu Kurakula, Xiao‐Qing Sun, Rolf M.F. Berger, Sébastien Bonnet, Harm Jan Bogaard, Marie‐José Goumans
0citations
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