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Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation2024 Cell Communication and Signaling article Medicine Orthopaedic implants and arthroplasty Open access
Aaron Babendreyer, Julia Kieselhorst, Cindy Rinkens, A. M. Lyashenko, Stefan Düsterhöft, Holger Jahr, +2 more
10citations -
Transferrin receptor 1 shedding by the pro-inflammatory iRhom–ADAM17 complex and ADAM10 regulates cellular iron uptake and ferroptosis2026 Experimental & Molecular Medicine article Medicine Ferroptosis and cancer prognosis Open access
Katharina Schun, Cindy Rinkens, Daniel Mehling, Yan Yu, Sarah Knapp, Carolin Peschke, +8 more
1citations -
In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators2022 International Journal of Molecular Sciences article Medicine HER2/EGFR in Cancer Research Open access cited by 1 patent
Marian Bienstein, Dmitriy Minond, Ulrich Schwaneberg, Mehdi D. Davari, Daniela Yildiz
13citations -
ADAM17 Is an Essential Factor for the Infection of Bovine Cells with Pestiviruses2022 Viruses article Agricultural and Biological Sciences Animal Disease Management and Epidemiology Open access
Marianne Zaruba, Hann-Wei Chen, Ole Frithjof Pietsch, Kati Szakmary-Braendle, Angelika Auer, Marlene Mötz, +5 more
15citations -
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity2024 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology 14-3-3 protein interactions Open access
Katharina Bläsius, Sarah Knapp, Charlotte Flaßhove, Friederike Sonnabend, Diandra T. Keller, Nikola Tacken, +8 more
12citations -
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine HER2/EGFR in Cancer Research Open access
Katharina Bläsius, Sarah Knapp, Charlotte Flaßhove, Friederike Sonnabend, Diandra T. Keller, Nikola Tacken, +8 more
1citations -
A structural model of the iRhom–ADAM17 sheddase complex reveals functional insights into its trafficking and activity2023 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Selcan Kahveci-Türköz, Katharina Bläsius, Justyna Wozniak, Cindy Rinkens, Anke Seifert, Petr Kašpárek, +9 more
18citations -
ADAM10 and ADAM17 differently mediate induced pulmonary ACE release by either direct proteolysis or indirect upregulation protein synthesis2026 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research article Medicine HER2/EGFR in Cancer Research Open access
Yan Yu, Aaron Babendreyer, Alessa Pabst, Anna Michely, Marie Tauscher, Christian Martin, +4 more
3citations -
Mechanoresponsive ion channels Piezo1 and TRPV4 stimulate ADAM10 and ADAM17 with differential impact on endothelial migration and proliferation2026 Cell Communication and Signaling article Medicine Erythrocyte Function and Pathophysiology Open access
Alessa Pabst, Nathalie Brock, Sofie Hardt, Caroline C. F. Grannemann, Hannah Kubiza, Anja Lena Thiebes, +2 more
6citations -
EGFR stimulation enables IL-6 trans-signalling via iRhom2-dependent ADAM17 activation in mammary epithelial cells2023 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research article Medicine HER2/EGFR in Cancer Research Open access
Neele Schumacher, Ilka Thomsen, Florian Brundert, Václav Hejret, Stefan Düsterhöft, Boris Tichý, +3 more
15citations -
A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Selcan Kahveci-Türköz, Katharina Bläsius, Cindy Rinkens, Anke Seifert, Petr Kašpárek, Henrike Ohm, +8 more
2citations