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ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination2022 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Seong-Ok Lee, Hsin‐Ru Chan, Martijn S. Luijsterburg, Justin W. C. Leung, Kyle M. Miller
39citations -
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks2020 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, +7 more
55citations -
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks2020 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Ignacio Alonso‐de Vega, Maria Cristina Paz‐Cabrera, Magdalena B. Rother, Wouter W. Wiegant, Cintia Checa-Rodríguez, Juan Ramon Hernandez-Fernaud, +4 more
35citations -
Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, Robin van Schendel, Marcel Tijsterman
38citations -
SENP6 regulates localization and nuclear condensation of DNA damage response proteins by group deSUMOylation2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Laura A. Claessens, Matty Verlaan–de Vries, Ilona J. de Graaf, Alfred C.O. Vertegaal
35citations -
Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner2020 PLoS Genetics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Alex N. Zelensky, Mascha Schoonakker, Inger Brandsma, Marcel Tijsterman, Dik C. van Gent, Jeroen Essers, +1 more
11citations -
Considerations for radiotherapy in Bloom Syndrome: A case series2021 European Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Michiel H. D. Schoenaker, Sanami Takada, Marcel van Deuren, Charlotte J. Dommering, Stefanie Henriet, Ingrid Pico, +5 more
9citations -
UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF1682024 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Zeliha Yalçin, Shiu Yeung Lam, Marieke H. Peuscher, Jaco van der Torre, Sha Zhu, Prasanna Vasudevan Iyengar, +10 more
7citations -
Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response2020 Molecular Cell article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Franziska Walser, Monique P. C. Mulder, Benoît Bragantini, Tatiana Gubser, Marco Gatti, Maria Victoria Botuyan, +6 more
57citations -
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Nature Communications article Medicine PARP inhibition in cancer therapy Open access cited by 18 patents
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +53 more
370citations -
Abstract P056: Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Molecular Cancer Therapeutics conference-abstract Medicine PARP inhibition in cancer therapy cited by 1 patent
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +42 more
3citations
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