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Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform distinct functional states within the regulatory and cytotoxic T cells2023 iScience article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Ashwin Jainarayanan, Nithishwer Mouroug-Anand, Edward H. Arbe-Barnes, Adam J. Bush, Rachael J. M. Bashford-Rogers, Adam Enver Frampton, +5 more
12citations -
EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia2021 Leukemia article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 2 patents
Philipp M. Roessner, Laura Llaó Cid, Ekaterina Lupar, Tobias Roider, Marie Bordas, Christoph Schifflers, +12 more
53citations -
Activated CD4+ T Cells and Highly Differentiated Alloreactive CD4+ T Cells Distinguish Operationally Tolerant Liver Transplantation Recipients2021 Liver Transplantation article Immunology and Microbiology T-cell and B-cell Immunology Open access
Aafke A. Duizendstra, Robert Jacobus de Knegt, Shanta Mancham, Mariska Klepper, Dave L. Roelen, Simone H. Brand‐Schaaf, +8 more
12citations -
Protocol for a mixed-methods modified Delphi study for the development of a core domain set to assess the health-related quality of life of patients with mycosis fungoides and Sézary syndrome in clinical trials
Christina Asare, Caroline Raymundo, Jennifer Chen, Lourdes Maria Perez-Chada, Marianne C. Tawa, Susan Thornton, +7 more
0citations -
Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement2025 Molecular Therapy Oncology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Erika A.K. Fletcher, Robert A. Cordfunke, Aikaterini Nasi, Gunilla Törnqvist, Rob R.P.M. Valentijn, Marita Westhrin, +19 more
3citations -
Guideline development for prevention of transfusion‐associated graft‐versus‐host disease: reduction of indications for irradiated blood components after prestorage leukodepletion of blood components
Johanna C. Wiersum‐Osselton, Jennichjen Slomp, J.H. Frederik Falkenburg, Tessa Geltink, Hans L. P. van Duijnhoven, Tanja Netelenbos, +1 more
12citations -
Defining nature, responses and drivers of regulatory- and conventional CD4+ T cells in the human term decidua2026 Frontiers in Immunology article Immunology and Microbiology Reproductive System and Pregnancy Open access
Lotte J. Verleng, Julia Busselaar, Mark Mensink, Ellen Schrama, Hanneke Kapsenberg, Carin van der Keur, +5 more
2citations -
Single-cell transcriptomics in bone marrow delineates CD56dimGranzymeK+ subset as intermediate stage in NK cell differentiation2022 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Monique M. van Ostaijen-ten Dam, Dorenda J. A. Schoorl, Pieter J. Schol, Daphne A. L. van den Homberg, Arjan C. Lankester, +2 more
17citations -
Reconstitution of the cellular niche requirements for primordial germ cell-like cell progression in humans2026 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm, Ioannis Moustakas, Albert Blanch-Asensio, Arend W. Overeem, +1 more
6citations -
Gene expression identifies patients who develop inflammatory arthritis in a clinically suspect arthralgia cohort2020 Arthritis Research & Therapy article Medicine Rheumatoid Arthritis Research and Therapies Open access
Ellis Niemantsverdriet, Erik B. van den Akker, Debbie M. Boeters, Susan J. F. van den Eeden, Annemieke Geluk, Annette H M van der Helm–van Mil
14citations -
Expression of immune checkpoint molecules on adult and neonatal T-cells2022 Immunologic Research article Immunology and Microbiology T-cell and B-cell Immunology Open access
Stefanie Dietz, Kriszta Molnár, Hannah Riedel, Bärbel Spring, Thorsten W Orlikowsky, Christian Friedrich Poets, +2 more
7citations -
Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis2021 PLoS ONE article Medicine Rheumatoid Arthritis Research and Therapies Open access cited by 1 patent
Linda M. Slot, Rochelle D. Vergroesen, Priscilla F. Kerkman, Ellen Magadalena Staudinger, Sanne Reijm, Hugo J. van Dooren, +4 more
9citations -
Alemtuzumab Exposure and T Lymphocyte Depletion: A Population Pharmacokinetic‐Pharmacodynamic Model of Alemtuzumab Induction Therapy for Kidney Transplantation2025 Clinical Pharmacology & Therapeutics article Medicine Renal Transplantation Outcomes and Treatments Open access
Lukas K. van Vugt, Tom C. Zwart, Suzanne Bezstarosti, Sebastiaan Heidt, Marlies E. J. Reinders, Dennis Alexander Hesselink, +3 more
3citations -
Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing2021 npj Regenerative Medicine article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Anika Schumacher, Maarten B. Rookmaaker, Jaap A. Joles, Rafael Kramann, Tri Quang Nguyen, Martijn van Griensven, +1 more
60citations -
Zinc deficiency impairs the development of human regulatory B cells from purified B cells2024 Journal of Trace Elements in Medicine and Biology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Mary-Ann Puppa, Sabrina Bianca Bennstein, Henrike Josephine Fischer, Lothar Rink
6citations -
Virus-Associated CD8 + T-Cells Are Not Activated Through Antigen-Mediated Interaction Inside Atherosclerotic Lesions2024 Arteriosclerosis Thrombosis and Vascular Biology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Maaike J.M. de Jong, Frank H. Schaftenaar, Marie A.C. Depuydt, Fernando Lozano Vigario, George M.C. Janssen, Judith A. H. M. Peeters, +7 more
10citations -
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease2021 International Journal of Molecular Sciences article Engineering 3D Printing in Biomedical Research Open access cited by 3 patents
Luuk de Haan, Johnny Suijker, Ruthger van Roey, Nina Berges, Elissaveta P. Petrova, Karla C. S. Queiroz, +5 more
83citations -
Human iPSC-derived preclinical models to identify toxicity of tumor-specific T cells with clinical potential2023 Molecular Therapy — Methods & Clinical Development article Medicine CAR-T cell therapy research Open access
Rosa A. van Amerongen, Laura T. Morton, Umesh Chaudhari, Dennis F.G. Remst, Renate S. Hagedoorn, Cathelijne W. van den Berg, +2 more
13citations