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Peripheral temperature dysregulation associated with functionally altered NaV1.8 channels2023 Pflügers Archiv - European Journal of Physiology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simon Loose, Annette Lischka, Samuel Kuehs, Carla Nau, Stefan H. Heinemann, Ingo Kurth, +1 more
7citations -
Sodium channels expressed in nociceptors contribute distinctly to action potential subthreshold phase, upstroke and shoulder2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Phil Alexander Köster, Enrico Leipold, Anna Maxion, Barbara Namer, Thomas Stiehl, Angelika Lampert
1citations -
Nociceptor sodium channels shape subthreshold phase, upstroke, and shoulder of action potentials2024 The Journal of General Physiology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Phil Alexander Köster, Enrico Leipold, Jenny Tigerholm, Anna Maxion, Barbara Namer, Thomas Stiehl, +1 more
23citations -
Two serial filters determine P2X7R cation selectivity, Ser342 in the central pore and lateral acidic residues at the cytoplasmic interface2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
F Markwárdt, Eike Schoen, Mihaela Raycheva, Aparna Sai Malisetty, Sanaria Hawro Yakoob, Malte Berthold, +1 more
0citations -
Carriers of SCN9A variants linked to inherited and acquired pain syndromes show no alteration in the prevalence of pain or analgesic usage in the UK Biobank cohort2025 medRxiv preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Graeme W. T. Newton, Corin Charman, Aidan P. Nickerson, Keith Geoffrey Phillips, Achim Kless, James Philip Dunham, +1 more
2citations -
Identification and functional analysis of two new de novo KCNMA1 variants associated with Liang–Wang syndrome2022 Acta Physiologica article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Lina Liang, Huihui Liu, Deborah Bartholdi, Arie van Haeringen, Alberto Fernández‐Jaén, Hongbo Xiong, +4 more
17citations -
Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms2025 eLife article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Hanna B. Kern, Christof Rickert, +4 more
4citations -
Modulating effects of FGF12 variants on Na V 1.2 and Na V 1.6 associated with Developmental and Epileptic Encephalopathy and Autism Spectrum Disorder2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simone Seiffert, Manuela Pendziwiat, Tatjana Bierhals, Himanshu Goel, Niklas Schwarz, Amelie T. van der Ven, +5 more
2citations -
Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms2024 eLife preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Christof Rickert, Oliver Kobler, +3 more
1citations -
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition2023 Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function
Maurice Dellin, Ina Rohrbeck, Purva Asrani, Julian Alexander Schreiber, Nadine Ritter, Frank Glorius, +14 more
3citations -
Depletion of membrane cholesterol modifies structure, dynamic and activation of Na v 1.72024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simone Albani, Vishal Sudha Bhagavath Eswaran, Alessia Piergentili, Paulo C. T. Souza, Angelika Lampert, Giulia Rossetti
0citations -
Depletion of membrane cholesterol modifies structure, dynamic and activation of Nav1.72024 International Journal of Biological Macromolecules article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simone Albani, Vishal Sudha Bhagavath Eswaran, Alessia Piergentili, Paulo C. T. Souza, Angelika Lampert, Giulia Rossetti
11citations -
Molecular Basis of CLC Antiporter Inhibition by Fluoride2020 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Maria Gabriella Chiariello, Viacheslav Bolnykh, Emiliano Ippoliti, Simone Meloni, Jógvan Magnus Haugaard Olsen, Thomas L. Beck, +3 more
37citations -
α‐Adrenoreceptor blocker phentolamine inhibits voltage‐gated sodium channels via the local anaesthetic binding site2025 British Journal of Pharmacology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Idil Toklucu, Vishal Sudha Bhagavath Eswaran, Raya Bott, Aylin Bilge Kesdoğan, Arnim Johannes Gaebler, Julia Stingl, +3 more
1citations -
Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study2022 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Titia Q. Ruijs, Ingrid W. Koopmans, Marieke L. de Kam, Michiel Joost van Esdonk, Martin Koltzenburg, Geert Jan Groeneveld, +1 more
7citations -
Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study2022 Clinical and Translational Science article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Titia Q. Ruijs, Ingrid W. Koopmans, Marieke L. de Kam, Martijn Rudolf Tannemaat, Geert Jan Groeneveld, Jules A. A. C. Heuberger
6citations -
Safety, Pharmacokinetics, and Pharmacodynamics of a First‐in‐Class ClC ‐1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial2024 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Titia Q. Ruijs, Catherine M.K.E. de Cuba, Jules A. A. C. Heuberger, Jane Bold, Thomas Skjærlund Grønnebæk, Klaus Gjervig Jensen, +13 more
4citations -
Mechanism underlying hooked resurgent-like tail currents induced by an insecticide in human cardiac Nav1.52020 Toxicology and Applied Pharmacology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Sarah Thull, Cristian Neacsu, Andrias O. O’Reilly, Stefanie Bothe, Ralf Hausmann, Tobias Huth, +2 more
6citations -
Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms2025 eLife article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Christopher Bell, Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Hanna B. Kern, +5 more
0citations