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T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immune Cell Function and Interaction Open access cited by 6 patents
Laura T. Morton, Tassilo L A Wachsmann, Miranda H. Meeuwsen, Anne K. Wouters, Dennis F.G. Remst, Marleen M. van Loenen, +2 more
34citations -
Ebola virus glycoprotein stimulates IL-18–dependent natural killer cell responses2020 Journal of Clinical Investigation article Immunology and Microbiology Immune Cell Function and Interaction Open access
Helen R. Wagstaffe, Elizabeth Clutterbuck, Viki Bockstal, Jeroen N. Stoop, Kerstin Lühn, Macaya Douoguih, +5 more
20citations -
Adaptive subsets limit the anti-tumoral NK-cell activity in Hepatocellular Carcinoma2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Charlotte Rennert, Catrin Tauber, Pia Fehrenbach, Kathrin Heim, Dominik Bettinger, Oezlem Sogukpinar, +10 more
3citations -
Antibody-dependent cellular cytotoxicity-inducing antibodies enhance the natural killer cell anti-cancer response against patient-derived pancreatic cancer organoids2023 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Nicky A. Beelen, Merel R. Aberle, Virginia Bruno, Steven W.M. Olde Damink, Gerard M.J. Bos, Sander S. Rensen, +1 more
23citations -
Protocol for Isolation, Stimulation and Functional Profiling of Primary and iPSC-derived Human NK Cells2020 BIO-PROTOCOL article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Maria Themeli, M. van Dam, Els van Beelen, Gertjan Lugthart, Rob C. Hoeben, +2 more
7citations -
Abstract A97: The inhibitory receptor NKG2A acts as a checkpoint on CD8 T cells in the context of cancer vaccines2020 Cancer Immunology Research conference-abstract Immunology and Microbiology Immune Cell Function and Interaction
Thorbald van Hall, Nadine van Montfoort, Linda Borst, Michael J. Korrer, Pascale André, Nicolai R. Wagtmann, +2 more
0citations -
Circumventing IFN-γ induced resistance in ovarian cancer with a double-hit: NKG2A knockout of PRAME-TCR expressing NK cells2026 Journal of Ovarian Research article Immunology and Microbiology Immune Cell Function and Interaction Open access
Els P. van Hees, Oliva W. Rensing, Renate S. Hagedoorn, Cilia R. Pothast, Anne K. Wouters, Rosa A. van Amerongen, +3 more
0citations -
A Single-Domain TCR-like Antibody Selective for the Qa-1b/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint2022 The Journal of Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Soroush Ghaffari, Katherine Upchurch, Susanne Gimlin, Trivendra Tripathi, Marjolein Sluijter, Jim Middelburg, +2 more
7citations -
496 Pre-clinical development of a TCRm antibody targeting MHC-E complexes presenting signal peptides from classical MHC class I disrupts the NKG2A:MHC-E immune checkpoint and promotes anti-tumor immunity2024 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology Immune Cell Function and Interaction Open access
Soroush Ghaffari, Katherine Upchurch, Gizem Oter, Susanne Gimlin, Debra Wawro-Weidanz, Thorbald van Hall, +1 more
0citations -
A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron G. Roberts, Supender Kaur, Aaron J. Ogden, Michael E. Divine, Gus D. Warren, Donghoon Kang, +8 more
2citations -
A functional screen for bacterial ubiquitin regulation identifies an unusual Pseudomonas aeruginosa E3 ligase2026 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron G. Roberts, Supender Kaur, Shun‐Je Bhark, Aaron J. Ogden, Michael E. Divine, Gus D. Warren, +9 more
0citations -
A gut meta-interactome map reveals modulation of human immunity by microbiome effectors2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Veronika Young, Bushra Dohai, Thomas C. A. Hitch, Patrick Hyden, Benjamin Weller, Niels S. van Heusden, +25 more
5citations -
SKIP‐HOPS recruits TBC1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport2020 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Cellular transport and secretion Open access
Marlieke L.M. Jongsma, Jeroen Bakker, Birol Cabukusta, Nalan Liv, Daphne M. van Elsland, Job Fermie, +10 more
120citations -
Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression2023 Frontiers in Immunology article Immunology and Microbiology Mast cells and histamine Open access
Sandro Capellmann, Herdit M. Schüler, Steffen K. Meurer, Lin Gan, Marlies Kauffmann, Katharina Horn, +4 more
6citations -
Transformation of primary murine peritoneal mast cells by constitutive KIT activation as a result of lost Cdkn2a/Arf expression2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Mast cells and histamine Open access
Sandro Capellmann, Herdit M. Schüler, Steffen K. Meurer, Lin Gan, Marlies Kauffmann, Katharina Horn, +4 more
0citations -
Logic-gated antibody pairs that selectively act on cells co-expressing two antigens2022 Nature Biotechnology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 7 patents
Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom, Michael J. Wester, Desiree Paulet, Kusai Al-Tamimi, +14 more
49citations -
CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool2024 Cancer Discovery article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 1 patent
Paulien Kaptein, Nadine Slingerland, Christina Metoikidou, Felix Prinz, Simone Brokamp, Mercedes Machuca-Ostos, +6 more
42citations