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Euplagia-1: A Phase 1/2 Trial of GLPG5201, a Fresh Stem-like Early Memory CD19 CAR T-Cell Therapy with a 7-Day Vein-to-Vein Time, in Patients with Relapsed/Refractory CLL and RT
Valentín Ortiz‐Maldonado, Núria Martínez‐Cibrián, Letícia Alserawan, Sergi Betriu, Ana Triguero, Sandra Blum, +8 more
5citations -
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment2023 Nature Communications article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 2 patents
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter, Greta Mattavelli, Patrick Eiring, +47 more
108citations -
Neonatal liver niches program T cell tolerance2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Eva-Lena Stange, Trong-Hieu Nguyen, D. Borrero Mendoza, Aiara Lobo Gomes, Marlene Sophia Kohlhepp, Jonas Pes, +23 more
0citations -
Ribosome profiling shows variable sensitivity to detect open reading frames for conventional and different types of cryptic T cell antigens2024 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Kyra J. Fuchs, Sofia Thomaidou, Arno R. van der Slik, Marian van de Meent, Peter A.C. ’t Hoen, J.H. Frederik Falkenburg, +2 more
1citations -
465 | LOW RATES OF HIGH‐GRADE TOXICITIES WITH GLPG5101, A FRESH, STEM‐LIKE, EARLY MEMORY PHENOTYPE ANTI‐CD19 CAR T‐CELL THERAPY IN PATIENTS WITH NHL IN THE ATALANTA‐1 STUDY
Joost S.P. Vermaat, Sébastien Anguille, Maria Theresa Kuipers, Pim G. N. J. Mutsaers, E. Willems, Michael Russell Bishop, +9 more
1citations -
Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry and high-resolution microscopy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Hiranmayi Ravichandran, André F. Rendeiro, Aharon G. Freud, Bethany L. Mundy-Bosse, +8 more
5citations -
Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141+ Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8+ T Cell Response in Human Immune System Mice2020 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Jing Huang, Jing Zhou, Reem Ghinnagow, Toshiyuki Seki, Sho Iketani, Daphnée Soulard, +5 more
27citations -
Mapping human natural killer cell development in tonsil2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Ansel P. Nalin, Hiranmayi Ravichandran, André F. Rendeiro, Bethany L. Mundy-Bosse, +9 more
0citations -
DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing2020 EBioMedicine article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 59 patents
Patrick J. Engelberts, Ida H. Hiemstra, Bart de Jong, Danita H. Schuurhuis, Joyce I. Meesters, Irati Beltrán Hernández, +10 more
181citations -
T-cell receptor repertoires against HLA class I-restricted minor histocompatibility antigens are highly diverse with a small subset of public clonotypes2026 Journal for ImmunoTherapy of Cancer article Medicine Hematopoietic Stem Cell Transplantation Open access
Kyra J. Fuchs, Marian van de Meent, Michel G D Kester, Renate S. Hagedoorn, Indu Khatri, Peter van Balen, +4 more
0citations -
Gamma Delta T-Cell Based Cancer Immunotherapy: Past-Present-Future2022 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 9 patents
José Saura‐Esteller, Milon de Jong, Lisa A. King, Erik Ensing, Benjamin Winograd, Tanja D. de Gruijl, +2 more
195citations -
Inhibiting the NADase CD38 improves cytomegalovirus-specific CD8+ T cell functionality and metabolism2024 Journal of Clinical Investigation article Medicine Cytomegalovirus and herpesvirus research Open access
Nils Mülling, Felix M. Behr, Graham A. Heieis, Kristina Boss, Suzanne van Duikeren, Floortje J. van Haften, +21 more
9citations -
Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer2020 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Esmé T.I. van der Gracht, Mark J.A. Schoonderwoerd, Suzanne van Duikeren, Ayse N Yilmaz, Felix M. Behr, Julia Colston, +7 more
24citations -
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia2022 Science Translational Medicine article Medicine CAR-T cell therapy research Open access cited by 2 patents
Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi, Farhatullah Syed, Hong Zhan, Annie Etuk, +52 more
204citations -
T-cell receptors targeting distinct FLT3-D835Y neoantigens display differential reactivity toward acute myeloid leukemia2026 Blood Immunology & Cellular Therapy article Medicine Acute Myeloid Leukemia Research Open access
Nadine Struckman, M. Willy Honders, Georgia Koutsoumpli, Rob C. M. de Jong, Dyantha I. van der Lee, Michel G.D. Kester, +11 more
0citations