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Design and rationale of the HARTc 2.0 trial: A multicenter randomized controlled study on the impact of point-of-care high-sensitivity cardiac troponin-I testing in prehospital acute coronary syndrome triage on diagnosis and cost-effectiveness
Anne Catherine M. H. van der Lande, Nina M. Diederiks, Enrico R. de Koning, Jan Bosch, Fred P.H.T.M. Romijn, Wouter P M van der Loo, +8 more
2citations -
Enhanced recovery and abbreviated length of anticoagulation for thromboprophylaxis after primary hip arthroplasty rationale and design of the ENABLE-hip trial2025 Journal of Thrombosis and Thrombolysis article Medicine Venous Thromboembolism Diagnosis and Management Open access
Philipp Drees, Irene M. Schmidtmann, Manuel Herbst, Stefano Barco, Frederikus Albertus Klok, Karsten Keller, +22 more
2citations -
The STArgardt Remofuscin Treatment Trial (STARTT): design and baseline characteristics of enrolled Stargardt patients2022 Open Research Europe article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Patty P.A. Dhooge, Philipp T. Möller, Camiel J. F. Boon, Andrew John Lotery, Philipp Herrmann, Maurízio Battaglia Parodi, +9 more
1citations -
DEB or DES for the treatment of calcified nodules after intravascular lithotripsy: the DEBSCAN-IVL trial design2025 REC interventional cardiology (English Edition) article Medicine Coronary Interventions and Diagnostics Open access
Alfonso Jurado-Román y, Mattia Basile, José M. Montero Cabezas, Borja Rivero Santana, Julio García-Tejada, Guillermo Galeote, +12 more
0citations -
Federated deep reinforcement learning based trajectory design for UAV-assisted networks with mobile ground devices2024 Scientific Reports article Engineering UAV Applications and Optimization Open access cited by 1 patent
Yunfei Gao, Mingliu Liu, Xiaopeng Yuan, Yulin Hu, Peng Sun, Anke Schmeink
23citations -
Randomized Evaluation of Surgery in Elderly with Traumatic Acute SubDural Hematoma (RESET-ASDH trial): study protocol for a pragmatic randomized controlled trial with multicenter parallel group design
Ranjit D. Singh, Jeroen T.J.M. van Dijck, Thomas Arjan van Essen, Hester Floor Lingsma, Suzanne Polinder, Erwin J. O. Kompanje, +5 more
13citations -
Effectiveness of a behavioral treatment protocol for selective mutism in children: Design of a randomized controlled trial2020 Contemporary Clinical Trials Communications article Psychology Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Open access
Chaya Rodrigues Pereira, Judith B. M. Ensink, Max G. Güldner, Kees Jan Kan, Maretha V. de Jonge, Ramón Lindauer, +1 more
10citations -
Reduced-Dose Intravenous Thrombolysis for Acute Intermediate–High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial2021 Thrombosis and Haemostasis article Medicine Venous Thromboembolism Diagnosis and Management Open access
Olivier Sanchez, Anaïs Charles‐Nelson, Walter Ageno, Stefano Barco, Harald Binder, Gilles Châtellier, +22 more
145citations -
Rationale and design of the Renal Lifecycle trial assessing the effect of dapagliflozin on cardiorenal outcomes in severe chronic kidney disease2025 Nephrology Dialysis Transplantation article Medicine Chronic Kidney Disease and Diabetes Open access
Wisanne M. Bakker, Hiddo J.L. Heerspink, Stefan P. Berger, Christoph Wanner, Sunil V. Badve, Clare Gabrielle Arnott, +80 more
33citations -
Efficacy and Safety of Low-Dose Digoxin in Patients with Heart Failure. Rationale and Design of the DECISION Trial2024 European Journal of Heart Failure article Medicine Heart Failure Treatment and Management Open access
Dirk J. van Veldhuisen, Michiel Rienstra, Arend Mosterd, A. Marco Alings, Antoinette D. I. van Asselt, Marcel L. Bouvy, +15 more
33citations -
A sexual rehabilitation intervention for women with gynaecological cancer receiving radiotherapy (SPARC study): design of a multicentre randomized controlled trial
Isabelle Suvaal, Susanna B. Hummel, Jan-Willem M. Mens, Helena C. van Doorn, Wilbert B. van den Hout, Carien L. Creutzberg, +1 more
17citations -
Rationale and design of the OPTIMIZE trial: OPen label multicenter randomized trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients
Silke E. de Boer, Jan‐Stephan Sanders, Fréderike J. Bemelman, Michiel G.H. Betjes, Johannes G. M. Burgerhof, Luuk B. Hilbrands, +7 more
16citations -
Study protocol: Effectiveness of dual-mobility cups compared with uni-polar cups for preventing dislocation after primary total hip arthroplasty in elderly patients — design of a randomized controlled trial nested in the Dutch Arthroplasty Registry
Loes W A H van Beers, Bart C. H. van der Wal, Tess Glastra van Loon, Dirk Jan F. Moojen, Marieke F. van Wier, Amanda D Klaassen, +2 more
15citations -
Efficacy and safety of early target-controlled plasma volume replacement with a balanced gelatine solution versus a balanced electrolyte solution in patients with severe sepsis/septic shock: study protocol, design, and rationale of a prospective, randomized, controlled, double-blind, multicentric, international clinical trial
Gernot Marx, Kai D. Zacharowski, Carole Ichaï, Karim Asehnoune, Vladimír Černý, Rolf Dembinski, +11 more
15citations -
Effectiveness of intramuscular gluteal glucocorticoid injection versus intra-articular glucocorticoid injection in knee osteoarthritis: design of a multicenter randomized, 24 weeks comparative parallel-group trial2020 BMC Musculoskeletal Disorders article Medicine Osteoarthritis Treatment and Mechanisms Open access
Marianne F. Mol, J. Runhaar, P.K. Bos, Desirée M. J. Dorleijn, Marijn Vis, Jacobijn Gussekloo, +2 more
13citations -
Heart Team risk assessment with angiography‐derived fractional flow reserve determining the optimal revascularization strategy in patients with multivessel disease: Trial design and rationale for the DECISION QFR randomized trial
Kotaro Miyata, Taku Asano, Akira Saito, Kohei Abe, Toru Tanigaki, Masahiro Hoshino, +26 more
6citations -
Design of VICTORION-2 Prevent: A randomized double-blind, placebo-controlled trial, assessing the impact of inclisiran on major adverse cardiovascular events in patients with established cardiovascular disease
Philippe Gabríel Steg, Shaun G. Goodman, J. Wouter Jukema, Pieter Martens, Andreas Zirlik, Deepak L. Bhatt, +9 more
6citations -
Design of the VOILA-intervention study: A 12-week nutrition and resistance exercise intervention in metabolic or mobility compromised Dutch older adults and the response on immune-metabolic, gut and muscle health parameters2024 Mechanisms of Ageing and Development article Medicine Nutrition and Health in Aging Open access cited by 1 patent
Alejandra P. Monsegue, Jordi Morwani‐Mangnani, Pol Grootswagers, Marian Beekman, P. Eline Slagboom, Lex B. Verdijk, +1 more
4citations -
Rationale and study design of a trial to assess rTMS add-on value for the amelioration of negative symptoms of schizophrenia (RADOVAN)2022 Contemporary Clinical Trials Communications article Neuroscience Transcranial Magnetic Stimulation Studies Open access
Tobias Hebel, Berthold Langguth, Martin Schecklmann, Stefan Schoisswohl, Susanne Staudinger, Axel Schiller, +9 more
4citations -
Virtual reality for psycho-education on self-stigma in depression: Design of a randomised controlled trial2022 Psychiatry Research Communications article Psychology Mental Health Treatment and Access Open access
Nancy Kramer Freher, Anika Bexkens, Martine van Bennekom, Wim Veling, Claudi Bockting
3citations