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C2orf69 mutations disrupt mitochondrial function and cause a multisystem human disorder with recurring autoinflammation2021 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Eva Lausberg, Sebastian Gießelmann, Joseph P. Dewulf, Elsa Wiame, Anja Holz, Ramona Salvarinova, +27 more
23citations -
Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells2023 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Jing Zhang, Maarten van Dinther, Midory Thorikay, Babak Mousavi Gourabi, Boudewijn P. T. Kruithof, Peter ten Dijke
20citations -
Targeting Sphingosine-1-Phosphate Signaling to Prevent the Progression of Aortic Valve Disease2024 Circulation article Biochemistry, Genetics and Molecular Biology Sphingolipid Metabolism and Signaling
Marcel Benkhoff, Maike Barcik, Philipp Mourikis, Jana Dahlmanns, Paulina Kahmann, Philipp Wollnitzke, +28 more
15citations -
T Cell Responses to Dystrophin in a Natural History Study of Duchenne Muscular Dystrophy2022 Human Gene Therapy article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Karen Anthony, Pierpaolo Ala, Francesco Catapano, Jinhong Meng, Joana Domingos, Mark M. Perry, +15 more
12citations -
Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research2025 Journal of the American Chemical Society article Medicine Cannabis and Cannabinoid Research Open access
Axel Hentsch, Mónica Guberman, Silke Radetzki, Mirjam C. W. Huizenga, Yingfang He, Jörg Contzen, +18 more
12citations -
Deciphering non-canonical ubiquitin signaling: biology and methodology2024 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Nila K. van Overbeek, Tim Aguirre, Gerbrand J. van der Heden van Noort, Blagoy Blagoev, Alfred C.O. Vertegaal
11citations -
Deubiquitinases in muscle physiology and disorders2024 Biochemical Society Transactions article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cyriel Sebastiaan Olie, Darragh Patrick O'Brien, Hannah B. L. Jones, Zhu Liang, Andreas Damianou, İlknur Sur‐Erdem, +3 more
8citations -
Validation of urinary biomarkers for accurate diagnosis of urinary tract infections in older adults across primary care, hospitals and long-term care facilities in the Netherlands and UK (UTI-GOLD): a multicentre observational study protocol
Nora el Moussaoui, Martha T. van der Beek, Jessica A. Vlot, Manu P. Bilsen, Cees van Nieuwkoop, Fanny N. Lauw, +14 more
6citations -
Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents2025 The Journal of Headache and Pain article Medicine Cannabis and Cannabinoid Research Open access
Georgii Krivoshein, Adriana Della Pietra, Juha R. Savinainen, Arn M. J. M. van den Maagdenberg, Rashid A. Giniatullin
5citations -
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche’s Endocannabinoid System Projects2024 CHIMIA International Journal for Chemistry article Medicine Cannabis and Cannabinoid Research Open access
Johannes D. Aebi, Kenneth Atz, Simon Mensah Ametamey, Jörg Benz, Julie Blaising, Stefania Butini, +37 more
4citations -
Immunogenicity and safety of different dose levels of Ad26.RSV.preF/RSV preF protein vaccine in adults aged 60 years and older: A randomized, double-blind, placebo-controlled, phase 2a study
Roy van Heesbeen, Arangassery Rosemary Bastian, Edmund V Ekoka Omoruyi, Christy A. Comeaux, Benoît Callendret, Esther Heijnen
4citations -
ER-embedded UBE2J1/RNF26 ubiquitylation complex in spatiotemporal control of the endolysosomal pathway2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular transport and secretion Open access
Tom Cremer, Marlieke L.M. Jongsma, Fredrik Trulsson, Alfred C.O. Vertegaal, Jacques Neefjes, Ilana Berlin
2citations -
A Phase 3, Randomized, Double-Blind, Active-Comparator-Controlled Study of Bomedemstat Versus Hydroxyurea in Patients with Essential Thrombocythemia Naïve to Cytoreductive Therapy2024 Blood conference-abstract Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Yuka Sugimoto, Eran Zimran, Yoshimitsu Shimomura, Hiroki Yamaguchi, Hans Carl Hasselbach, Jean‐Jacques Kiladjian, +14 more
2citations -
Attenuating pulmonary injury and inflammation with C5/CD14 inhibition therapy: results from a porcine polytrauma model with blunt chest trauma2026 European Journal of Trauma and Emergency Surgery article Medicine Trauma Management and Diagnosis Open access
Ümit Mert, Rald V. M. Groven, Kang Qin, Johannes Greven, Elizabeth Rosado Balmayor, Tom Eirik Mollnes, +4 more
2citations -
Deciphering the Specificity of Reversible DNA-Phosphate ADP-Ribosylation via the Precise Synthesis and Enzymatic Profiling of Nucleotide-Phospho-ADP-Ribosyl Probes2026 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology DNA and Nucleic Acid Chemistry
Li Liu, Yang Lu, Zongxing Yu, Li Tang, Y N Wu, Jim Voorneveld, +4 more
1citations