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496 Pre-clinical development of a TCRm antibody targeting MHC-E complexes presenting signal peptides from classical MHC class I disrupts the NKG2A:MHC-E immune checkpoint and promotes anti-tumor immunity2024 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology Immune Cell Function and Interaction Open access
Soroush Ghaffari, Katherine Upchurch, Gizem Oter, Susanne Gimlin, Debra Wawro-Weidanz, Thorbald van Hall, +1 more
0citations -
Deleterious variants inCRLS1lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease2022 Human Molecular Genetics article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Richard G. Lee, Shanti Balasubramaniam, Maike Stentenbach, Thomas Kralj, Tim McCubbin, Benjamin Scott Padman, +23 more
42citations -
Blood-brain barrier perturbations by uremic toxins: Key contributors in chronic kidney disease-induced neurological disorders?2023 European Journal of Pharmaceutical Sciences article Neuroscience Barrier Structure and Function Studies Open access
Quentin Faucher, Thomas K. van der Made, Elizabeth C. M. de Lange, Rosalinde Masereeuw
42citations -
Molecular pathophysiology of human MICU1 deficiency2021 Neuropathology and Applied Neurobiology article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Nicolai Kohlschmidt, Miriam Elbracht, Artur Czech, Martin Häusler, Vietxuan Phan, Ana Töpf, +12 more
33citations -
Pyramidal cell types drive functionally distinct cortical activity patterns during decision-making2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neural dynamics and brain function Open access
Simon Musall, Xiaonan Richard Sun, Hemanth Mohan, Xu An, Steven Gluf, Shu-Jing Li, +6 more
26citations -
Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Ivar Noordstra, Cyntha M. van den Berg, Fransje W. J. Boot, Eugene A. Katrukha, Ka Lou Yu, Roderick P. Tas, +8 more
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Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)–H Bond Functionalization2020 Inorganic Chemistry article Chemistry Organometallic Complex Synthesis and Catalysis Open access
Shunsuke Kato, Akira Onoda, Alexander R. Grimm, Kengo Tachikawa, Ulrich Schwaneberg, Takashi Hayashi
20citations -
Fast Simulation of a Multi-Area Spiking Network Model of Macaque Cortex on an MPI-GPU Cluster2022 Frontiers in Neuroinformatics article Neuroscience Neural dynamics and brain function Open access
Gianmarco Tiddia, Bruno Golosio, Jasper Albers, Johanna Senk, Francesco Simula, Jari Pronold, +4 more
17citations -
Robust principal component analysis‐based prediction of protein‐protein interaction hot spots2021 Proteins Structure Function and Bioinformatics article Biochemistry, Genetics and Molecular Biology Machine Learning in Bioinformatics Open access
Divya Sitani, Alejandro Giorgetti, Mercedes Alfonso‐Prieto, Paolo Carloni
17citations