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ESTRO consensus guidelines on GTV delineation and dose-escalation in rectal cancer2026 Clinical and Translational Radiation Oncology article Medicine Colorectal Cancer Surgical Treatments Open access
Giuditta Chiloiro, Angela Romano, Regina G. H. Beets‐Tan, Krzysztof Bujko, Davide Cusumano, Emmanouil Fokas, +10 more
0citations -
2417P De-escalation of therapy with androgen receptor pathway inhibitors or docetaxel by using PSMA PET/CT in metastatic castration-resistant prostate cancer patients: study results from a Dutch cohort
Kim J. M. van der Velden, Sietse van Mossel, Fleur Kleiburg, Lioe‐Fee de Geus‐Oei, Tom van der Hulle, Malou C. P. Kuppen, +3 more
0citations -
De-escalation of axillary treatment in the event of a positive sentinel lymph node biopsy in cT1–2 N0 breast cancer treated with mastectomy: nationwide registry study (BOOG 2013-07)2024 British journal of surgery article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Sabine Rosalie de Wild, Lori M. van Roozendaal, Johannes H.W. de Wilt, Thijs van Dalen, Jos A. van der Hage, Frederieke H van Duijnhoven, +14 more
17citations -
1128P A phase I dose escalation and expansion study of FHD-286, a novel BRG1/BRM (SMARCA4/SMARCA2) inhibitor, for the treatment of metastatic uveal melanoma
Sapna Pradyuman Patel, Meredith Ann McKean, S. Piperno-Neumann, Alexander Noor Shoushtari, Leonel Fernando Hernandez-Aya, Marlana M. Orloff, +11 more
6citations -
1176P Open-label, dose escalation, phase I/II study to assess safety, tolerability, immunogenicity and preliminary clinical activity of the therapeutic cancer vaccine PDC*lung01 with or without anti-programmed death-1 (PD-1) treatment in patients with non-small cell lung cancer (NSCLC)2022 Annals of Oncology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
J.F. Vansteenkiste, I. Demedts, E. Pons-Tostivint, B. Biesma, F. Borm, B. Colinet, +14 more
5citations -
1623MO Ripretinib intra-patient dose escalation (IPDE) following disease progression provides clinically meaningful progression-free survival (PFS) in gastrointestinal stromal tumor (GIST) in phase I study
Filip Jankú, Ping Chi, Michael Charles Heinrich, Margaret von Mehren, Robin L. Jones, Kristen N. Ganjoo, +9 more
4citations -
De-escalation of axillary treatment in case of a positive sentinel lymph node biopsy in cT1-2N0 breast cancer treated with mastectomy: a nationwide registry study to provide insight into prognosis2024 European Journal of Surgical Oncology article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies
Sabine De Wild, Lori van Roozendaal, Hans De Wilt, Thijs van Dalen, Jos A. van der Hage, Frederieke H van Duijnhoven, +14 more
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POS0684 OMNIPRESENT POOR PROGNOSTIC FACTORS IN EARLY RHEUMATOID ARTHRITIS IN THE IMPROVED COHORT; IS EARLIER BDMARD TREATMENT ESCALATION NECESSARY FOR EVERYONE?2024 Annals of the Rheumatic Diseases conference-abstract Medicine Rheumatoid Arthritis Research and Therapies
Sytske Anne Bergstra, JA van der Pol, Tom W. J. Huizinga, M Steup-Beekman, Cornelia F Allaart
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Delivering high-quality multiple sclerosis care in Germany: challenges and regional models2026 Neurological Research and Practice article Medicine Multiple Sclerosis Research Studies Open access
Marc Pawlitzki, Niklas Huntemann, Lars Masanneck, Noah M. Werner, Julian Zimmermann, Thomas Postert, +7 more
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Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer2024 ESMO Open article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Leonora W. de Boo, Katarzyna Jóźwiak, Natalie D. ter Hoeve, P. J. van Diest, Mark Opdam, Yuwei Wang, +44 more
12citations -
Management of recurrent venous thromboembolism during anticoagulant treatment in patients with cancer: a prospective cohort study2025 Journal of Thrombosis and Haemostasis article Medicine Venous Thromboembolism Diagnosis and Management Open access
Vincent R. Lanting, Floris T.M. Bosch, Emily S.L. Martens, Pieter Willem Kamphuisen, Stefano Barco, Ramón Lecumberri, +11 more
5citations -
P537: SAFETY AND TOLERABILITY OF AZD0466 AS MONOTHERAPY FOR PATIENTS WITH ADVANCED HEMATOLOGICAL MALIGNANCIES - PRELIMINARY RESULTS FROM AN ONGOING PHASE I/II TRIAL2023 HemaSphere article Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation Open access
Giovanni Marconi, Shukaib Arslan, Shaun A. Fleming, Antonio Curti, James Stewart Blachly, Giovanni Martinelli, +15 more
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Correction: Designing integrated early-phase protocols to reduce substantial modifications, including considerations for patient cohorts – a multi-stakeholder consensus view for a practical approach in Germany2026 Frontiers in Pharmacology erratum Mathematics Statistical Methods in Clinical Trials Open access
Robert Schultz-Heienbrok, S. Baumann, R. Böhm, Andreas Bonertz, K. Breithaupt-Groegler, U. Buckpesch-Heberer, +13 more
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Value of MRI and ultrasound for prediction of therapeutic response and erosive progression in patients with early rheumatoid arthritis managed by an aggressive treat-to-target strategy
Ulf Sundin, Nina Paulshus Sundlisæter, Anna‐Birgitte Aga, Joseph Sexton, Lena Bugge Nordberg, Hilde Berner Hammer, +4 more
29citations -
A multicenter, dose-finding, phase 1b study of imatinib in combination with alpelisib as third-line treatment in patients with advanced gastrointestinal stromal tumor
Maria Abbondanza Pantaleo, Michael Charles Heinrich, Antoîne Italiano, Claudia María Valverde, Patrick Schöffski, Giovanni Grignani, +8 more
11citations