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α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity2022 Proceedings of the National Academy of Sciences article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Simona S. Ghanem, Nour K. Majbour, Nishant N. Vaikath, Mustafa Taleb Ardah, Daniel Erskine, Nanna Møller Jensen, +15 more
218citations -
Stopping Renin-Angiotensin System Inhibitors in Patients with Advanced CKD and Risk of Adverse Outcomes: A Nationwide Study2020 Journal of the American Society of Nephrology article Medicine Chronic Kidney Disease and Diabetes Open access
Edouard L. Fu, Marie Evans, Catherine M. Clase, Laurie A. Tomlinson, Merel van Diepen, Friedo Wilhelm Dekker, +1 more
199citations -
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II2020 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Yana van der Weegen, Hadar Golan-Berman, Tycho E.T. Mevissen, Katja Apelt, Román González‐Prieto, Joachim Goedhart, +6 more
185citations -
Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study2021 Cancers article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Maggie Banys‐Paluchowski, Maria Luisa Gasparri, Jana de Boniface, Oreste Gentilini, Elmar Stickeler, Steffi Hartmann, +23 more
166citations -
Mineral resources in life cycle impact assessment: part II – recommendations on application-dependent use of existing methods and on future method development needs2020 The International Journal of Life Cycle Assessment article Environmental Science Environmental Impact and Sustainability Open access
Markus Berger, Thomas Sonderegger, Rodrigo A.F. Alvarenga, Vanessa Bach, Alexander Cimprich, Jo P. Dewulf, +16 more
158citations -
LifeTime and improving European healthcare through cell-based interceptive medicine2020 Nature article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Nikolaus Rajewsky, Geneviève Almouzni, Stanislaw A. Gorski, Stein Aerts, Ido Amit, Michela Giulia Bertero, +91 more
154citations -
Hemophagocytic lymphohistiocytosis in adults: collaborative analysis of 137 cases of a nationwide German registry2020 Journal of Cancer Research and Clinical Oncology article Medicine Autoimmune and Inflammatory Disorders Research Open access
Sebastian Birndt, B. Heinevetter, Frank Martin Brunkhorst, Georg Maschmeyer, Frank Rothmann, Thomas Weber, +13 more
137citations -
Diagnosis and treatment of neurogenic dysphagia – S1 guideline of the German Society of Neurology2021 Neurological Research and Practice article Health Professions Dysphagia Assessment and Management Open access
Rainer Dziewas, Hans–Dieter Allescher, Ilia Aroyo, Gudrun Bartolome, Ulrike Beilenhoff, Jörg Edgar Bohlender, +19 more
131citations -
Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials2022 The Lancet Diabetes & Endocrinology article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Adem Y. Dawed, Andrea Mari, Andrew Anand Brown, Timothy James McDonald, Lin Li, Shuaicheng Wang, +79 more
129citations -
Measuring the Human Dimensions of Digital Leadership for Successful Digital Transformation2022 Research-Technology Management article Business, Management and Accounting Corporate Management and Leadership
Haroon R. Abbu, Paul Mugge, Gerhard Gudergan, Gerrit Hoeborn, Alexander Kwiatkowski
123citations -
Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients2022 European Journal of Endocrinology article Medicine Pituitary Gland Disorders and Treatments Open access
Pia Burman, Jacqueline Trouillas, Marco Losa, A I McCormack, Stephan Petersenn, Marily Theodoropoulou, +59 more
109citations -
Recommendations for tilt table testing and other provocative cardiovascular autonomic tests in conditions that may cause transient loss of consciousness2021 Clinical Autonomic Research article Medicine Cardiovascular Syncope and Autonomic Disorders Open access
Roland D. Thijs, Michele Brignole, Cristian Falup‐Pecurariu, Alessandra Fanciulli, Roy L. Freeman, Pietro Guaraldi, +9 more
106citations -
Effect of Prolonged Exposure, intensified Prolonged Exposure and STAIR+Prolonged Exposure in patients with PTSD related to childhood abuse: a randomized controlled trial2021 European Journal of Psychotraumatology article Psychology Posttraumatic Stress Disorder Research Open access
Danielle A. C. Oprel, Chris Maria Hoeboer, Maartje Schoorl, Rianne A. de Kleine, Marylène Cloître, Ingrid G. Wigard, +2 more
106citations -
Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells
Ploingarm Petsophonsakul, Mathias Burgmaier, Brecht A. G. Willems, Sylvia Heeneman, Nadina Stadler, Felix Gremse, +11 more
106citations -
NETs-Induced Thrombosis Impacts on Cardiovascular and Chronic Kidney Disease2023 Circulation Research article Immunology and Microbiology Neutrophil, Myeloperoxidase and Oxidative Mechanisms Open access
Manovriti Thakur, Carolina Victória Cruz Junho, Sarah Bernhard, Marc Schindewolf, Heidi Noels, Yvonne Döring
105citations -
Methodology over metrics: current scientific standards are a disservice to patients and society2021 Journal of Clinical Epidemiology article Decision Sciences Meta-analysis and systematic reviews Open access
Ben Van Calster, Laure Wynants, Richard D Riley, Maarten van Smeden, Professor Gary S. Collins
103citations -
Effect of Smartphone-Enabled Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial Infarction2020 JAMA Network Open article Health Professions Mobile Health and mHealth Applications Open access
Roderick Willem Treskes, Loes A. M. van Winden, Nicole van Keulen, Enno Tjeerd van der Velde, Saskia L.M.A. Beeres, Douwe E. Atsma, +1 more
100citations -
The NORMAN Association and the European Partnership for Chemicals Risk Assessment (PARC): let’s cooperate!2020 Environmental Sciences Europe article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Valeria Dulio, Jan Koschorreck, Bert van Bavel, Paul J. Van den Brink, Juliane Hollender, John Munthe, +62 more
100citations -
Joint Final Report of EORTC 26951 and RTOG 9402: Phase III Trials With Procarbazine, Lomustine, and Vincristine Chemotherapy for Anaplastic Oligodendroglial Tumors
Andrew B. Lassman, Khê Hoang‐Xuan, Mei‐Yin C. Polley, Alba Ariela Brandes, John Gregory Cairncross, Johan M. Kros, +14 more
96citations