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Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells2022 Science Advances article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Florian Szymczak, Maria Inês Alvelos, Sandra Marín‐Cañas, Ângela Castela, Stéphane Demine, Máikel L. Colli, +6 more
39citations -
IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels2023 American Journal of Respiratory and Critical Care Medicine article Immunology and Microbiology IL-33, ST2, and ILC Pathways Open access
Alen Faiz, Rashad Mohammad Mahbub, Fia Sabrina Boedijono, Milan I. Tomassen, Wierd Kooistra, Wim Timens, +25 more
43citations -
Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects2022 eLife article Biochemistry, Genetics and Molecular Biology Protein Tyrosine Phosphatases Open access
Maja Šolman, Sasja Blokzijl-Franke, Florian Piques, Chuan Yan, Qiqi Yang, Marion Strullu, +6 more
30citations -
Resident Memory T Cells in the Atherosclerotic Lesion Associate With Reduced Macrophage Content and Increased Lesion Stability2024 Arteriosclerosis Thrombosis and Vascular Biology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Maaike J.M. de Jong, Marie A.C. Depuydt, Frank H. Schaftenaar, K C Liu, David Maters, Anouk Wezel, +5 more
17citations -
MMR vaccination induces a trained immunity program characterized by functional and metabolic reprogramming of γδ T cells2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune responses and vaccinations
Rutger Jan Röring, Priya A. Debisarun, Javier Botey-Bataller, Tsz Kin Suen, Ozlem Pinar Bulut, Gizem Kılıç, +19 more
4citations -
Gut microbiota mediates trafficking of intestinal T cells to the brain to exacerbate neuroinflammation after ischemic stroke2025 Research Square preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Zhuang Li, Nannan Guo, Xiangyu Zuo, Jinlian Shao, Fabing Zhang, Yu Xiao, +19 more
0citations -
Barley Ror1 encodes a class XI myosin required for mlo‐based broad‐spectrum resistance to the fungal powdery mildew pathogen2022 The Plant Journal article Agricultural and Biological Sciences Powdery Mildew Fungal Diseases Open access
Johanna Acevedo‐Garcia, Kim D. Walden, Franz Leissing, Kira Baumgarten, Katarzyna Drwiega, Mark Kwaaitaal, +12 more
11citations -
Epicardial differentiation drives fibro-fatty remodeling in arrhythmogenic cardiomyopathy2021 Science Translational Medicine article Medicine Cardiovascular Effects of Exercise Open access cited by 1 patent
Arwa Kohela, Sebastiaan J. van Kampen, Tara Moens, Martijn Wehrens, Bas Molenaar, Cornelis J.J. Boogerd, +6 more
45citations -
Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Francesco Limone, Jana M. Mitchell, Irune Guerra San Juan, Janell L.M. Smith, Kavya Raghunathan, Sulagna Dia Ghosh, +8 more
6citations -
Leukemia inhibitory factor receptor inhibition reduces stenosis grade and total serum cholesterol levels in a mouse model for atherosclerosis2024 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Esmeralda Hemme, MAC Depuydt, Peter J. van Santbrink, Lucie Delfos, Johan Kuiper, Ilze Bot
0citations -
Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Bilal Unal, Omer F. Kuzu, Yang Jin, Wanja Kildal, Manohar Pradhan, Sonia H.Y. Kung, +7 more
40citations -
Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice2024 Science Translational Medicine article Medicine Amyotrophic Lateral Sclerosis Research Open access cited by 1 patent
Francesco Limone, Yingying Zhang, Blake T. McCourt, Cerianne Huang, Adina Minkin, Marghi Jani, +7 more
16citations -
Human pluripotent stem cells-derived inner ear organoids recapitulate otic development in vitro2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Hearing, Cochlea, Tinnitus, Genetics Open access
Daniela Doda, Sara Alonso Jimenez, Hubert Rehrauer, Jose F. Carreño, Victoria Valsamides, Stefano Di Santo, +7 more
1citations -
Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy2020 Disease Models & Mechanisms article Medicine Aortic Disease and Treatment Approaches Open access
Joshua Craiger Peterson, Lambertus J. Wisse, Valerie Wirokromo, Tessa van Herwaarden, Anke M. Smits, Adriana C. Gittenberger–de Groot, +4 more
19citations -
A resource for generating and manipulating human microglial states in vitro2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Michael-John Dolan, Martine Therrien, Saša Jereb, Tushar Kamath, Trevor Atkeson, Samuel E. Marsh, +16 more
12citations