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Diet and exercise reduce pre-existing NASH and fibrosis and have additional beneficial effects on the vasculature, adipose tissue and skeletal muscle via organ-crosstalk
Anita M. van den Hoek, Jelle C. B. C. de Jong, Nicole Worms, Anita van Nieuwkoop, Marijke Voskuilen, Aswin L. Menke, +4 more
53citations -
Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells2020 Stem Cell Research article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access cited by 1 patent
Poulomi Banerjee, Evdokia Paza, Emma Perkins, Owen G. James, Boyd Kenkhuis, Amy F. Lloyd, +8 more
53citations -
Transcriptional response to host chemical cues underpins the expansion of host range in a fungal plant pathogen lineage2021 The ISME Journal article Agricultural and Biological Sciences Plant pathogens and resistance mechanisms Open access
Stefan Kusch, Justine Larrouy, Heba M. M. Ibrahim, Shantala Mounichetty, Noémie Gasset, Olivier Navaud, +6 more
53citations -
EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia2021 Leukemia article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 2 patents
Philipp M. Roessner, Laura Llaó Cid, Ekaterina Lupar, Tobias Roider, Marie Bordas, Christoph Schifflers, +12 more
53citations -
Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages2020 Environmental Microbiology article Environmental Science Bacteriophages and microbial interactions Open access
Cédric Lood, Katarzyna M. Danis-Wlodarczyk, Bob G. Blasdel, Ho Bin Jang, Dieter Vandenheuvel, Yves Briers, +4 more
52citations -
Network integration and modelling of dynamic drug responses at multi-omics levels2020 Communications Biology article Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access cited by 1 patent
Nathalie Selevsek, Florian Caiment, Ramona Nudischer, Hans Gmuender, Irina V. Agarkova, Francis L. Atkinson, +37 more
51citations -
RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells2025 Proceedings of the National Academy of Sciences article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Hamsa Narasimhan, Maria Lucia Richter, Ramin Shakiba, Nikos E. Papaioannou, Christina Stehle, Kaushikk Ravi Rengarajan, +23 more
51citations -
A comprehensive database for integrated analysis of omics data in autoimmune diseases2021 BMC Bioinformatics article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Jordi Martorell‐Marugán, Raúl López-Domínguez, Adrián García-Moreno, Daniel Toro Dominguez, Juan Antonio Villatoro-García, Guillermo Barturen, +10 more
51citations -
Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in Crohn’s disease2024 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Bo-Jun Ke, Saeed Abdurahiman, Francesca Biscu, Gaia Zanella, Gabriele Dragoni, Sneha Santhosh, +22 more
50citations -
Conserved white-rot enzymatic mechanism for wood decay in the Basidiomycota genus Pycnoporus2020 DNA Research article Agricultural and Biological Sciences Enzyme-mediated dye degradation Open access
Shingo Miyauchi, Hayat Hage, Élodie Drula, Laurence Lesage‐Meessen, Jean‐Guy Berrin, David Navarro, +35 more
49citations -
Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol2023 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Kim van Kuijk, Ian R McCracken, Renée J. H. A. Tillie, S. Asselberghs, Dlzar Ali Kheder, Stan Muitjens, +22 more
48citations -
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease2021 Frontiers in Genetics article Medicine Celiac Disease Research and Management Open access cited by 1 patent
Adriaan van der Graaf, Maria Magdalena Zorro, Annique Claringbould, Urmo Võsa, Raúl Aguirre‐Gamboa, Chan Li, +13 more
48citations -
Enzyme-Constrained Models and Omics Analysis of Streptomyces coelicolor Reveal Metabolic Changes that Enhance Heterologous Production2020 iScience article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Snorre Sulheim, Tjaša Kumelj, Dino van Dissel, Ali Salehzadeh‐Yazdi, Chao Du, Kay Nieselt, +3 more
46citations -
AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype2023 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, Ioannis Moustakas, Thilo M. Buck, Christiaan H. Arendzen, +4 more
46citations -
The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids2023 Communications Biology article Biochemistry, Genetics and Molecular Biology Plant biochemistry and biosynthesis Open access
Emily Amor Stander, Beata Joanna Lehka, Inês Carqueijeiro, Clément Cuello, Frederik G. Hansson, Hans J. Jansen, +17 more
45citations