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Long-term results of the NECK trial—implanting a disc prosthesis after cervical anterior discectomy cannot prevent adjacent segment disease: five-year clinical follow-up of a double-blinded randomised controlled trial
Caroline M.W. Goedmakers, Floor E. de Vries, Lisette Bosscher, Wilco C. Peul, Mark P. Arts, Carmen L. A. Vleggeert-Lankamp
26citations -
Rationale and design of the OPTIMIZE trial: OPen label multicenter randomized trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients
Silke E. de Boer, Jan‐Stephan Sanders, Fréderike J. Bemelman, Michiel G.H. Betjes, Johannes G. M. Burgerhof, Luuk B. Hilbrands, +7 more
16citations -
Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial2026 Clinical and Experimental Ophthalmology article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Jonathan Hensman, Hind Almushattat, Roselie M.H. Diederen, Tien‐En Tan, Peilun Dai, Coen de Vente, +10 more
3citations -
Long‐term follow‐up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half‐dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4
Helena M. A. Feenstra, Issam el Mansori, Thomas J. van Rijssen, Roula Tsonaka, Roselie M.H. Diederen, Carel B. Hoyng, +3 more
0citations -
796. P02.05 NEOADJUVANT CHEMORADIOTHERAPY FOLLOWED BY ACTIVE SURVEILLANCE VERSUS STANDARD SURGERY FOR OESOPHAGEAL CANCER (SANO-TRIAL): A MULTICENTRE STEPPED-WEDGE CLUSTER-RANDOMISED NONINFERIORITY TRIAL
Berend J. van der Wilk, Ben M. Eyck, Bas P. L. Wijnhoven, Sjoerd M. Lagarde, Camiel Rosman, Bo Jan Noordman, +28 more
1citations -
RIFAMPICIN COMBINATION THERAPY VERSUS TARGETED ANTIMICROBIAL MONOTHERAPY IN THE ORAL ANTIMICROBIAL TREATMENT PHASE OF STAPHYLOCOCCAL PROSTHETIC JOINT INFECTION (RICOTTA-TRIAL): PROTOCOL FOR A RANDOMIZED, CONTROLLED, OPEN-LABEL, NON-INFERIORITY TRIAL
Jaap L.J. Hanssen, Karin M. Veerman, Olav van der Jagt, Matthijs Paul Somford, Jolanda Lammers, Rudolf Wilhelm Poolman, +12 more
2citations -
An exploratory open-label multicentre phase I/II trial evaluating the safety and efficacy of postnatal or prenatal and postnatal administration of allogeneic expanded fetal mesenchymal stem cells for the treatment of severe osteogenesis imperfecta in infants and fetuses: the BOOSTB4 trial protocol2024 BMJ Open article Biochemistry, Genetics and Molecular Biology Connective tissue disorders research Open access
Eva Åström, Lyn S. Chitty, Belinda Crowe, Anna Louise David, Catherine J DeVile, Annabelle Forsmark, +17 more
25citations -
An adaptive phase II/III safety and efficacy randomized controlled trial of single day or three-day fixed-dose albendazole-ivermectin co-formulation versus albendazole for the treatment of Trichuris trichiura and other STH infections. ALIVE trial protocol2022 Gates Open Research article Immunology and Microbiology Parasites and Host Interactions Open access
Alejandro Javier Krolewiecki, Wendemagegn Enbiale, Javier Gandasegui, Lisette van Lieshout, Stella Kepha, Augusto Messa, +15 more
16citations -
Physiological-based cord clamping in very preterm infants: the Aeration, Breathing, Clamping 3 (ABC3) trial—statistical analysis plan for a multicenter randomized controlled trial
Sten Paul Willemsen, Ronny Knol, Emma Brouwer, Thomas van den Akker, Philip L J DeKoninck, Enrico Lopriore, +14 more
4citations -
Implementation of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial): study protocol for a stepped-wedge cluster-randomized controlled trial
Florence E.M. de Rijk, Charlotte L. van Veldhuisen, Marc G. Besselink, Jeanin Elise van Hooft, Hjalmar C. van Santvoort, Erwin J. M. van Geenen, +4 more
10citations -
Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial
Eva V. Vodegel, Sandra E. Zwolsman, Astrid Vollebregt, Ruben G. Duijnhoven, Judith Ekkina Bosmans, Leonie Speksnijder, +20 more
7citations -
The effectiveness of intratympanic injections with methylPREDnisolon versus placebo in the treatment of vertigo attacks in MENière’s disease (PREDMEN trial): a study protocol for a phase-3 multicentre, double-blinded, randomised, placebo-controlled trial
Maud Boreel, Babette F. van Esch, Tjard R. Schermer, Berber M. Mol, Peter Paul G. van Benthem, Tjasse Doewe Bruintjes
2citations -
PeRsonalIsed MEdicine in Rheumatoid Arthritis (PRIMERA) trial: a multicentre, open-label, randomised controlled trial comparing routine care with a tailor-made approach
Hamit Harun Dağ, Agnes E M Looijen, Harald E. Vonkeman, Annemiek Willemze, Lindy‐Anne Korswagen, Roos C Padmos, +8 more
2citations -
HERNIIA-II trial (Hernia Endoscopic oR opeN repair In chIldren Analysis): a protocol of a multicentre randomised controlled trial to study the (cost-)effectiveness of laparoscopic hernia repair compared to open hernia repair in children 0–16 years
Sanne C Maat, Lore Elise de Vreeze, Roxanne Eurlings, Johannes R. Anema, Robertine van Baren, Jasper V. Been, +15 more
0citations -
Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a fasting-mimicking diet in patients with type 2 diabetes
Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske van den Akker‐van Marle, Ko Willems van Dijk, Valter Daniel Longo, +3 more
28citations -
Procedural sedation and analgesia versus general anesthesia for hysteroscopic myomectomy (PROSECCO trial): A multicenter randomized controlled trial
Julia F. van der Meulen, Marlies Y. Bongers, Lisa G. van der Zee, Ruben G. Duijnhoven, Robert Adrianus de Leeuw, Lucilla E. Overdijk, +13 more
6citations -
The GALANT trial: study protocol of a randomised placebo-controlled trial in patients with a 68 Ga -DOTATATE PET-positive, clinically non-functioning pituitary macroadenoma on the effect of lan reotide on t umour size
Tessel M. Boertien, Madeleine L. Drent, Jan Booij, Charles B.L.M. Majoie, Marcel P. M. Stokkel, Jantien Hoogmoed, +7 more
4citations -
BRASD trial: biomechanical reposition techniques in anterior shoulder dislocation—a randomized multicenter clinical trial2023 International Journal of Emergency Medicine article Medicine Shoulder Injury and Treatment Open access
David Baden, Martijn H. Roetman, Tom Boeije, Nieke Mullaart, Ralph Boden, Roderick Marijn Houwert, +3 more
3citations -
Effect of a prediction tool and communication skills training on communication of treatment outcomes: a multicenter stepped wedge clinical trial (the SOURCE trial)2023 EClinicalMedicine article Health Professions Patient-Provider Communication in Healthcare Open access
Loïs F van de Water, Steven C. Kuijper, Inge Henselmans, E.N. van Alphen, Eefje S. Kooij, Mart M Calff, +14 more
8citations