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Rational evolution of a recombinant DNA polymerase for efficient incorporation of unnatural nucleotides by dual-site boosting2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Ruyin Cao, Lili Zhai, Qingqing Xie, Zi Wang, Yue Zheng, Wenwei Zhang, +5 more
0citations -
KIRA6 is an effective and versatile mast cell inhibitor of IgE-mediated activation2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Mast cells and histamine Open access
Veronika Wunderle, Thomas Wilhelm, Shatha Boukeileh, Jonas Goßen, Michael A. Margreiter, Roman Sakurov, +10 more
0citations -
Visualizing the mechanism of quinol oxidation and inhibition of a bd -type oxidase using cryo-EM2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Materials Science Enzyme Structure and Function Open access
Tijn T. van der Velden, Kanwal Kayastha, Famke Pelser, Steffen Brünle, Lars J. C. Jeuken
0citations -
Discovery of a novel chemotype targeting Mycobacterium tuberculosis cytochrome bd through rapid screening and structural elucidation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Tijn T. van der Velden, Asad Halimi, J.P.V. Pols, Wing-Sam Lam, Stephan M. Hacker, Lars J. C. Jeuken
0citations -
RRE-Finder: A Genome-Mining Tool for Class-Independent RiPP Discovery2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Microbial Natural Products and Biosynthesis Open access
Alexander Kloosterman, Kyle E. Shelton, Gilles P. van Wezel, Marnix H. Medema, Douglas A. Mitchell
15citations -
Investigating Enzyme Function by Geometric Matching of Catalytic Motifs2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Ioannis G. Riziotis, Martin F. Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton
2citations -
Huib32: A Potent and Selective USP32 Inhibitor Modulating Endosomal Processes and Advancing Cell-Permeable USP32 Probes2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Stephan Scherpe, Vito Pol, Raymond Kooij, Adán Pinto-Fernández, Rayman T.N. Tjokrodirijo, Darragh Patrick O'Brien, +6 more
1citations -
Structures of Arabidopsis thaliana MDL Proteins and Synergistic Effects with the Cytokine MIF on Human Receptors2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Macrophage Migration Inhibitory Factor Open access
Lukas Spiller, R. Manjula, Franz Leissing, J. Basquin, Priscila Bourilhon, Dzmitry Sinitski, +8 more
0citations