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Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Antitumor Activity of the Cyclin-Dependent Kinase-9 (CDK9) Inhibitor AZD4573 in Relapsed/Refractory Hematological Malignancies: A Phase 1 First-in-Human Study
Tim H. Brümmendorf, Patrick G. Medd, Raphael Koch, Stephan Stilgenbauer, Shringi Sharma, Yun He, +4 more
8citations -
Spontaneous vasomotion propagates along pial arterioles in the awake mouse brain like stimulus-evoked vascular reactivity2023 Journal of Cerebral Blood Flow & Metabolism article Neuroscience Barrier Structure and Function Studies Open access
Leon P. Munting, Orla Bonnar, Mariel G. Kozberg, Corinne A. Auger, Lydiane Hirschler, Steven S. Hou, +3 more
26citations -
Induction of Cure in Early Arthritis (I CEA): study protocol for an investigator-initiated randomized single-blind clinical trial with open-label extension to compare three treatment strategies in patients with newly diagnosed undifferentiated arthritis
Sytske Anne Bergstra, Lotte van Ouwerkerk, Isabell S Nevins, Joy Ardjuna van der Pol, G S Helmich, I Hest, +9 more
1citations -
Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues2023 Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Francesco Limone, Irune Guerra San Juan, Jana M. Mitchell, Janell L.M. Smith, Kavya Raghunathan, Daniel Meyer, +12 more
55citations -
Linking altered neuronal and synaptic properties to nicotinic receptor Alpha5 subunit gene dysfunction: a translational investigation in rat mPFC and human cortical layer 62025 Translational Psychiatry article Biochemistry, Genetics and Molecular Biology Nicotinic Acetylcholine Receptors Study Open access
Danqing Yang, Guanxiao Qi, Daniel Delev, Uwe Maskos, Dirk Feldmeyer
7citations -
Type-I interferon shapes peritoneal immunity in cirrhosis and drives caspase-5-mediated progranulin release upon infection2024 Journal of Hepatology article Immunology and Microbiology interferon and immune responses Open access
Michael D. Rooney, Shivalee N. Duduskar, Mohamed Ghait, Johanna Reißing, Sven Stengel, Philipp Alexander Reuken, +8 more
15citations -
The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype2023 BMC Plant Biology article Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Liming Zhao, Haojie Wang, Patrícia Dalcin Martins, Joost Thomas van Dongen, Anthony Bolger, Romy Schmidt, +3 more
8citations