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When Data Are Lacking: Physics-Based Inverse Design of Biopolymers Interacting with Complex, Fluid Phases2024 Journal of Chemical Theory and Computation article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Jeroen Methorst, Niek van Hilten, Art Hoti, Kai Steffen Stroh, Herre Jelger Risselada
10citations -
A first step towards best practice recommendations for the design and statistical analyses of pragmatic clinical trials: A modified Delphi approach2022 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Victoria Palin, Tjeerd Pieter van Staa, Stephanie Steels, Andrea B. Troxel, Rolf H. H. Groenwold, Thomas MacLennan MacDonald, +7 more
6citations -
A randomized embedded multifactorial adaptive platform for extra corporeal membrane oxygenation (REMAP ECMO) – design and rationale of the left ventricular unloading trial domain
Myrthe P. J. van Steenwijk, Joost van Rosmalen, Carlos V. Elzo Kraemer, Dirk Wilhelm Donker, Jeannine A. J. M. Hermens, Adriaan O. Kraaijeveld, +20 more
5citations -
Ultrasound-facilitated, catheter-directed thrombolysis vs anticoagulation alone for acute intermediate-high-risk pulmonary embolism: Rationale and design of the HI-PEITHO study2022 American Heart Journal article Medicine Venous Thromboembolism Diagnosis and Management Open access
Frederikus Albertus Klok, Gregory Piazza, Andrew S. P. Sharp, Fionnuala Ní Áinle, Michael R. Jaff, Nikhil Chauhan, +10 more
214citations -
Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and/or chronic kidney disease: Design and baseline characteristics of SOUL , a randomized trial
Darren K. McGuire, Rodica Pop‐Busui, John Eric Deanfield, Silvio E. Inzucchi, Johannes F.E. Mann, Nikolaus Marx, +8 more
133citations -
Rationale and design of the RISC trial: a multicenter RCT to assess in hospital 24 hour observation with telemetry of syncope patients admitted to the cardiac emergency room and emergency department
Thomas Boel, Suzanne Peeters, Martin E W Hemels, Mariam Samim, Egbert M. Koomen, Jaco H. Houtgraaf, +8 more
1citations -
Rationale, Design, and Baseline Clinical Characteristics of the Ziltivekimab Cardiovascular Outcomes Trial2025 JAMA Cardiology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases
Paul M. Ridker, Florian M.M. Baeres, Anders Hvelplund, Mads D.M. Engelmann, G. Kees Hovingh, Abraham Michael Lincoff, +5 more
62citations -
Balsa: A Fast C++ Random Forest Classifier with Command-line and Python Interface2026 Zenodo (CERN European Organization for Nuclear Research) software Computer Science Machine Learning and Data Classification Open access
Tobias Borsdorff, Denis de Leeuw Duarte, Joris van Zwieten, S. Mandal, Jochen Landgraf
0citations -
Balsa: A Fast C++ Random Forest Classifier with Command-line and Python Interface2026 Zenodo (CERN European Organization for Nuclear Research) software Computer Science Machine Learning and Data Classification Open access
Tobias Borsdorff, Denis de Leeuw Duarte, Joris van Zwieten, S. Mandal, Jochen Landgraf
0citations -
Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study2023 Thrombosis and Haemostasis article Health Professions Medical Coding and Health Information Open access
Behnood Bikdeli, Ying-Chih Lo, Candrika D. Khairani, Antoine Bejjani, David Jiménez, Shiwani Mahajan, +18 more
25citations -
Study protocol: DexaDays-2, hydrocortisone for treatment of dexamethasone-induced neurobehavioral side effects in pediatric leukemia patients: a double-blind placebo controlled randomized intervention study with cross-over design
Annelienke M. van Hulst, Emma J. Verwaaijen, Marta F. Fiocco, Saskia M.F. Pluijm, Martha Alexandra Grootenhuis, Rob Pieters, +2 more
10citations -
Hydrocortisone or Placebo to Reduce Dexamethasone-Induced Neurobehavioral Side Effects: Results of a Phase 3 National, Double-Blind, Placebo-Controlled Randomized Trial with Crossover Design
Annelienke M. van Hulst, Erica L T van den Akker, Emma J. Verwaaijen, Marta F. Fiocco, Niki Rensen, Raphaële R. L. van Litsenburg, +7 more
0citations