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A Framework for NGN1-Induced Sensory Neuron Differentiation for Disease Modelling and Drug Screening2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Anika Neureiter, Marlene Menke, Veronica Donde, Cedric Guenther, Lennart Mueller, Florian Kraft, +10 more
0citations -
Protocol for generating megakaryocytes from patient induced pluripotent stem cells for disease modeling and compound screening2026 STAR Protocols article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Payal Chawla, Niclas Flosdorf, Marcelo AS de Toledo, Martin Zenke
0citations -
Expanding the phenotypic spectrum of MECOM-associated syndrome: rare variants are associated with syndromic pulmonary arterial hypertension.2025 Apollo (University of Cambridge) article Medicine Pulmonary Hypertension Research and Treatments Open access
Carrie L. Welch, Meriel McEntagart, Shahin Moledina, Cara Morgan, Emilia M. Swietlik, Chao Hou, +17 more
0citations -
Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR-Based Functional Screening of Osteoporosis Candidate Genes2020 Journal of Bone and Mineral Research article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan R. Metz, +4 more
44citations -
Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR-based functional screening of osteoporosis candidate genes2021 Bone Reports article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan R. Metz, +4 more
4citations -
Comparative Evaluation of a Dietary Fiber Mixture in an Intestinal Screening Platform and a Crossover Intervention Study2024 conference-paper Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Femke P. M. Hoevenaars, Tim J. van den Broek, Boukje C. Eveleens Maarse, Matthijs Moerland, Ines Warnke, Hannah M. Eggink, +1 more
0citations -
Clinical challenges following early detection of ataxia telangiectasia through SCID newborn screening2025 Journal of Human Immunity review Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Thomas J. Weitering, Dagmar Berghuis, Maartje Blom, Michèl A.A.P. Willemsen, Mirjam van der Burg
2citations -
Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Tessa de Korte, Georgios Kosmidis, Benoit Samson-Couterie, Mervyn P.H. Mol, Ruben W.J. van Helden, Viviana Meraviglia, +7 more
1citations -
A fluorescence-based sensor screen identifies MED12 as a potential microsatellite instability regulator in colon cancer2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Genetic factors in colorectal cancer Open access
João M. Fernandes Neto, Subramanian Venkatesan, Matheus de Souza Dias, Cor Lieftink, Ben Morris, Kaspar Bresser, +6 more
0citations -
Screening of a genome‐reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion2020 Microbial Biotechnology article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Johannes Hemmerich, Carmen Steffens, Sebastian J. Reich, Marc Weiske, Meike Baumgart, Christian Rückert, +6 more
29citations -
Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters2022 Frontiers in Pharmacology article Biochemistry, Genetics and Molecular Biology Amino Acid Enzymes and Metabolism Open access
Hubert J. Sijben, Laura Dall’ Acqua, Rongfang Liu, Eirini Christodoulaki, Svenja Onstein, Gernot Wolf, +6 more
9citations -
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis2021 Genome biology article Biochemistry, Genetics and Molecular Biology Hippo pathway signaling and YAP/TAZ Open access
Li Li, Alejandro Pineiro Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel, Jin Ma, +16 more
24citations -
A High Content Imaging and Machine Learning Approach to Identify the Anti-Cancer Effect of Novel Small Molecules on Brain Cancer Patient-Derived Organoids2025 Microscopy and Microanalysis article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Rizwan Ali, Yassinali Tamboli, Saba M. Alsubaie, Sikander Hayat, Mohamed Boudjelal
0citations -
Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Jakob Gierten, Christian Pylatiuk, Omar T. Hammouda, Christian Schock, Johannes Stegmaier, Joachim Wittbrodt, +2 more
109citations -
Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions2021 Nanoscale Horizons article Materials Science Nanoparticles: synthesis and applications Open access
Luı́s M.B.B. Estronca, Vítor Francisco, Patrícia R. Pitrez, Inês Agapito Honório, Lara Carvalho, Helena Vazão, +7 more
12citations -
In vitro Three-Dimensional Sprouting Assay of Angiogenesis using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing2021 Journal of Visualized Experiments article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer cited by 2 patents
Georgios Galaris, Jérémy H. Thalgott, Eliott Teston, Franck Lebrin
4citations -
Modeling Hepatocellular Carcinoma and its microenvironment on a chip Hepatocellular carcinoma PDChip2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Orsola Mocellin, Stéphane Treillard, Abbie Robinson, Aleksandra Olczyk, Thomas Olivier, Chee Ping Ng, +9 more
1citations -
P.13 What is the future for female patients with childhood onset symptomatic Duchenne muscular dystrophy?2022 Neuromuscular Disorders article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders
S. Houwen van Opstal, R. Tak, M. Pelsma, Hermine van Duyvenvoorde, Edith H. C. Cup, Aad Verrips, +5 more
0citations -
Clinical impact of additional findings detected by genome-wide non-invasive prenatal testing: Follow-up results of the TRIDENT-2 study2022 The American Journal of Human Genetics article Medicine Prenatal Screening and Diagnostics Open access
Lisanne van Prooyen Schuurman, Erik A. Sistermans, Diane Van Opstal, Lidewij Henneman, Mireille N. Bekker, Caroline J. Bax, +28 more
98citations