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1623MO Ripretinib intra-patient dose escalation (IPDE) following disease progression provides clinically meaningful progression-free survival (PFS) in gastrointestinal stromal tumor (GIST) in phase I study
Filip Jankú, Ping Chi, Michael Charles Heinrich, Margaret von Mehren, Robin L. Jones, Kristen N. Ganjoo, +9 more
4citations -
1622MO Clinical benefit with ripretinib as ≥4th line treatment in patients with advanced gastrointestinal stromal tumors (GIST): Update from the phase III INVICTUS study
John Raymond Zalcberg, Michael Charles Heinrich, Suzanne George, Sebastian Bauer, Hans A. J. Gelderblom, Patrick Schöffski, +12 more
1citations -
Epithelial PDGF-C Contributes to Crescentic Glomerulonephritis and FSGS in Part via Activation of Parietal Epithelial Cells2026 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies
Ina Verena Martin, Yingying Gao, Dickson W.L. Wong, Roman David Bülow, Mirna Barsoum, Lisa Nguyen, +14 more
0citations -
Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS): a double-blind, randomised, placebo-controlled, phase 3 trial2020 The Lancet Oncology article Medicine Gastrointestinal Tumor Research and Treatment Open access cited by 48 patents
Jean‐Yves Blay, César Serrano, Michael Charles Heinrich, John Raymond Zalcberg, Sebastian Bauer, Hans A. J. Gelderblom, +11 more
430citations -
Patient-reported outcomes in individuals with advanced gastrointestinal stromal tumor treated with ripretinib in the fourth-line setting: analysis from the phase 3 INVICTUS trial
Patrick Schöffski, Suzanne George, Michael Charles Heinrich, John Raymond Zalcberg, Sebastian Bauer, Hans A. J. Gelderblom, +12 more
10citations -
A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex2025 eLife preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Cecilia Hes, Abigail J. Tomlinson, Lieke Michielsen, Hunter J Murdoch, Maia V. Kokoeva, Paul V. Sabatini
5citations -
Safety profile of ripretinib, including impact of alopecia, and Palmar-Plantar Erythrodysesthesia Syndrome (PPES) on patient-reported outcomes (PROs), in ≥ fourth-line advanced gastrointestinal stromal tumors (GIST): Analyses from INVICTUS.2020 Journal of Clinical Oncology conference-abstract Medicine Gastrointestinal Tumor Research and Treatment
Suzanne George, Michael Charles Heinrich, John Raymond Zalcberg, Sebastian Bauer, Hans A. J. Gelderblom, Patrick Schöffski, +12 more
4citations -
A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex2025 eLife article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Cecilia Hes, Abigail J. Tomlinson, Lieke Michielsen, Hunter J Murdoch, Maia V. Kokoeva, Paul V. Sabatini
0citations