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Bidirectional crosstalk between epithelial-mesenchymal plasticity and IFNγ-induced PD-L1 expression promotes tumor progression2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Cells and Metastasis Open access
Gerhard A. Burger, Daphne Nesenberend, Carlijn M. Lems, Sander C. Hille, Joost B. Beltman
1citations -
Immune-related Gene Expression Predicts Response to Neoadjuvant Chemotherapy but not Additional Benefit from PD-L1 Inhibition in Women with Early Triple-negative Breast Cancer2021 Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies
Bruno Valentin Sinn, Sibylle Loibl, Claus Alexander Hanusch, Dirk-Michael Zahm, Hans‐Peter Sinn, Michael Untch, +16 more
46citations -
Tolerability and efficacy of the cancer vaccine UV1 in patients with recurrent or metastatic PD-L1 positive head and neck squamous cell carcinoma planned for first-line treatment with pembrolizumab – the randomized phase 2 FOCUS trial
Anna Paula Brandt, Christoph Schultheiß, Konrad Friedrich Klinghammer, Philippe Schafhausen, Chia‐Jung Busch, Markus Blaurock, +8 more
11citations -
TGF-β and PD-L1 inhibition combined with definitive chemoradiotherapy in esophageal squamous cell carcinoma: A phase II clinical trial (NCT04595149).2021 Journal of Clinical Oncology conference-abstract Medicine Esophageal Cancer Research and Treatment
Linde M. Veen, Maarten C.C.M. Hulshof, Connie R. Jiménez, Edwin P. J. G. Cuppen, Laurens Victor Beerepoot, Geert‐Jan Creemers, +9 more
2citations -
Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer
Raimundo Fernandes de Araújo Júnior, George Alexandre Lira, Timo Schomann, Rômulo S. Cavalcante, Natalia Feitosa Vilar, Regina C.M. de Paula, +6 more
19citations -
Intradermal immunization with Plasmodium berghei late-arresting genetically attenuated sporozoites induces PD-L1 expression on regulatory macrophages and dendritic cells
Roos van Schuijlenburg, Chanel Milène Naar, Helena M. de Bes-Roeleveld, Séverine Chevalley, Lili A. Zigó, Emma L. Houlder, +4 more
0citations -
A text-mining approach to study the real-world effectiveness and potentially fatal immune-related adverse events of PD-1 and PD-L1 inhibitors in older patients with stage III/IV non-small cell lung cancer
Hanieh Abedian Kalkhoran, J. Zwaveling, Bert N. Storm, Sylvia A. van Laar, Johanneke E.A. Portielje, Henk Codrington, +4 more
14citations -
Effective combination of liposome-targeted chemotherapy and PD-L1 blockade of murine colon cancer2022 Journal of Controlled Release article Materials Science Nanoparticle-Based Drug Delivery Open access
Zili Gu, Candido G. Da Silva, Timo Schomann, Marcel G M Camps, Koen van der Maaden, Qi Liu, +2 more
43citations -
PD-L1 expression in bladder cancer: Which scoring algorithm in what tissue?2021 Urologic Oncology Seminars and Original Investigations article Medicine Cancer Immunotherapy and Biomarkers
Gerald Bastian Schulz, Rumyana Todorova, Till A. Braunschweig, Severin Rodler, Yannic Volz, Lennert Eismann, +6 more
14citations -
614P TGF-β and PD-L1 inhibition with bintrafusp alfa combined with definitive chemoradiation therapy for esophageal squamous cell carcinoma (Tapestry): A single-arm, phase II, investigator-initiated, multicenter, feasibility study
Demi Wekking, Linde M. Veen, Peter S.N. van Rossum, Debby E. Geijsen, Laurens Victor Beerepoot, Irene E.G. van Hellemond, +14 more
0citations -
293 Acidosis promotes immune escape through the IFN-γ-induced induction of PD-L1 transcription in cancer cells2023 Journal of Investigative Dermatology article Medicine Cancer Immunotherapy and Biomarkers Open access
Dimitri Stowbur, P. Knopf, S. Hoffmann, V. Buchner, M. Poxleitner, I. Gonzalez-Menendez, +11 more
0citations -
UV1 cancer vaccine in pembrolizumab-treated patients with recurrent or metastatic PD-L1 positive head and neck squamous cell carcinoma: results from the randomized phase 2 FOCUS trial
Anna Paula Brandt, Konrad Friedrich Klinghammer, Christoph Schultheiß, Lisa Paschold, Claudia Wickenhauser, Marcus Bauer, +17 more
1citations -
89Zr-durvalumab PD-L1 PET in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck.2020 Journal of Clinical Oncology conference-abstract Medicine Radiopharmaceutical Chemistry and Applications Open access
Sarah R. Verhoeff, Pim P. van de Donk, Erik H.J.G. Aarntzen, Iris H.C. Miedema, Sjoukje F. Oosting, Jens Voortman, +4 more
12citations