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Progression-free survival and overall survival after BRCA1/2-associated epithelial ovarian cancer: A matched cohort study2022 PLoS ONE article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Bernadette A. M. Heemskerk‐Gerritsen, Antoinette Hollestelle, Christi J. van Asperen, Irma van de Beek, Willemien J. van Driel, Klaartje van Engelen, +6 more
8citations -
Breast cancer risks associated with missense variants in breast cancer susceptibility genes2022 Genome Medicine article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Leila Dorling, Sara Carvalho, Jamie Allen, Michael T. Parsons, Cristina Fortuño, Anna González‐Neira, +90 more
60citations -
The impact of coding germline variants on contralateral breast cancer risk and survival2023 The American Journal of Human Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Anna Morra, Nasim Mavaddat, Taru Muranen, Thomas U. Ahearn, Jamie Allen, Irene Louise Andrulis, +90 more
28citations -
High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors2023 Journal of Clinical Oncology article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Iris A.S. Stroot, Joost Bart, Harry Hollema, Denise J. Stommel-Jenner, Marise M. Wagner, Helena C. van Doorn, +15 more
15citations -
PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants2023 npj Breast Cancer article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Taru Muranen, Anna Morra, Sofia Khan, Daniel R. Barnes, Manjeet K. Bolla, Joe Dennis, +61 more
7citations -
EXO1 protects BRCA1-deficient cells against toxic DNA lesions2024 Molecular Cell article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 2 patents
Bert van de Kooij, Anne Schreuder, Raphael Pavani, Veronica Garzero, Sidrit Uruci, Tiemen J. Wendel, +13 more
44citations -
Salpingectomy With Delayed Oophorectomy Versus Salpingo‐Oophorectomy in BRCA1/2 Carriers: Three‐Year Outcomes of a Prospective Preference Trial2025 BJOG An International Journal of Obstetrics & Gynaecology article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Majke H.D. van Bommel, Miranda P. Steenbeek, Joanna IntHout, Tessa Van Garderen, Marline G. Harmsen, Angela H.E.M. Maas, +16 more
17citations -
Validation of the BOADICEA model in a prospective cohort of BRCA1/2 pathogenic variant carriers2024 Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Xin Yang, Thea M. Mooij, Goska Leslie, Lorenzo Ficorella, Nadine Andrieu, Karin Kast, +34 more
16citations -
Prevalence of germline pathogenic variants in 779 patients with metastatic prostate cancer2025 British Journal of Urology article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Michiel Vlaming, Wouter Koole, R. Jeroen A. van Moorselaar, Eveline M. A. Bleiker, Ellen van de Geer, Hanneke W. M. van Deutekom, +11 more
3citations -
Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes2022 JAMA Oncology article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Nasim Mavaddat, Leila Dorling, Jamie Allen, Anna González‐Neira, Renske Keeman, Manjeet K. Bolla, +85 more
171citations -
Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in BRCA1/2 Pathogenic Variant Carriers2021 JAMA Oncology article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Miranda P. Steenbeek, Marline G. Harmsen, Angela H.E.M. Maas, Judith B. Prins, Johan Bulten, Steven Teerenstra, +17 more
85citations -
Polygenic risk modeling for prediction of epithelial ovarian cancer risk2022 European Journal of Human Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Eileen Dareng, Jonathan P. Tyrer, Daniel R. Barnes, Michelle R. Jones, Xin Yang, Muriel A. Adank, +60 more
71citations -
Multi-gene panel testing and association analysis in Cypriot breast cancer cases and controls2023 Frontiers in Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Maria Zanti, Maria A. Loizidou, Denise G O'Mahony, Leila Dorling, Joe Dennis, Peter Devilee, +4 more
2citations -
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Nature Communications article Medicine PARP inhibition in cancer therapy Open access cited by 18 patents
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +53 more
370citations -
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study2022 Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Xin Yang, Mikael Eriksson, Kamila Czene, Andrew Lee, Goska Leslie, Michael J. Lush, +9 more
98citations -
Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk2023 Nature Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Naomi Wilcox, Martine Dumont, Anna González‐Neira, Charles Joly Beauparlant, Marco Crotti, Craig Luccarini, +56 more
67citations -
RAD51 as a functional biomarker for homologous recombination deficiency in cancer: a promising addition to the HRD toolbox?2021 Expert Review of Molecular Diagnostics article Medicine PARP inhibition in cancer therapy Open access cited by 1 patent
Lise M. van Wijk, Andreea B. Nilas, Harry Vrieling, Maaike P.G. Vreeswijk
37citations -
RNA transcripts regulate G-quadruplex landscapes through G-loop formation2025 Science article Biochemistry, Genetics and Molecular Biology DNA and Nucleic Acid Chemistry Open access
Koichi Sato, Jing Lyu, Jeroen van den Berg, Victoria M. Cruz, Joost Schimmel, Clara Esteban-Jurado, +7 more
36citations -
Germline variants in DNA repair genes, including BRCA1/2, may cause familial myeloproliferative neoplasms2021 Blood Advances article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Miriam Elbracht, Robert Meyer, Kim Kricheldorf, Deniz Gezer, Thomas Eggermann, Beate Betz, +6 more
17citations -
Rare germline copy number variants (CNVs) and breast cancer risk2022 Communications Biology article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Joe Dennis, Jonathan P. Tyrer, Logan C. Walker, Kyriaki Michailidou, Leila Dorling, Manjeet K. Bolla, +88 more
15citations -
Clinically Relevant Germline Variants in Children With Nonmedullary Thyroid Cancer2024 The Journal of Clinical Endocrinology & Metabolism article Medicine Thyroid Cancer Diagnosis and Treatment Open access
Karin van der Tuin, Dina Ruano, Jeroen Knijnenburg, Rob B. van der Luijt, Hans Morreau, Thera P. Links, +20 more
14citations