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Integrin α1β1 Promotes Interstitial Fibrosis and Cyst Growth in a Mouse Model of Polycystic Kidney Disease2025 Journal of the American Society of Nephrology article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Céline Grenier, I‐Hsuan Lin, Dorien J.M. Peters, Ambra Pozzi, Rachel Lennon, Richard William Naylor
5citations -
IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p2024 Journal of Translational Medicine article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Ehsan Gharib, Leili Rejali, Moein Piroozkhah, Elham Zonoobi, Parinaz Nasri Nasrabadi, Zahra Arabsorkhi, +6 more
13citations -
IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels2023 American Journal of Respiratory and Critical Care Medicine article Immunology and Microbiology IL-33, ST2, and ILC Pathways Open access
Alen Faiz, Rashad Mohammad Mahbub, Fia Sabrina Boedijono, Milan I. Tomassen, Wierd Kooistra, Wim Timens, +25 more
43citations -
Novel Type 2-high gene clusters associated with corticosteroid sensitivity in COPD2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Alen Faiz, Stelios Pavlidis, C-H.S. Kuo, Anthony Rowe, Pieter Sicco Hiemstra, Wim Timens, +9 more
2citations -
Maturation of hiPSC-derived cardiomyocytes in cardiac microtissues promotes adult alternative splicing of sodium channel revealing mutation effects associated with cardiac arrhythmia
Giulia Campostrini, Dorien Ward‐van Oostwaard, Georgios Kosmidis, Arie O. Verkerk, CR Bezzina, CL Mummery, +1 more
2citations -
P0106 Profiling inflammation-associated T helper subsets in Inflammatory Bowel Disease2025 Journal of Crohn s and Colitis conference-abstract Medicine Inflammatory Bowel Disease Open access
Qing Jiang, Ciska Lindelauf, Laura F. Ouboter, Frits Koning, Andrea E. van der Meulen‐de Jong, Vincent van Unen, +1 more
0citations -
Thermal Runaway Safety and Mitigation in Lithiumion Battery Packs Using Immersion Cooling for Electric Vehicles and Next Generation Aircraft2026 IEEE Transportation Electrification Conference and Expo conference-paper Engineering Battery Modeling and Management Open access
Abdul Wahab, Bhargav Shiva Sai Vanjarapu, Nima Amjady, Hans Kemper, Hamid Khayyam
0citations -
A unified design allows fine-tuning of biosensor parameters and application across bacterial species2020 Metabolic Engineering Communications article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Christiane Katharina Sonntag, Lion Konstantin Flachbart, Celine Maass, Jan Marienhagen
19citations -
An adeno-associated virus gene therapy strategy for anti-obesity treatment by nanocarrier-based delivery systems2025 Journal of Nanobiotechnology article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Li Li, Wang Wang, Rong Li, Jiayue Guo, Xulin Hu, Yu Pan, +6 more
4citations -
Epicardial differentiation drives fibro-fatty remodeling in arrhythmogenic cardiomyopathy2021 Science Translational Medicine article Medicine Cardiovascular Effects of Exercise Open access cited by 1 patent
Arwa Kohela, Sebastiaan J. van Kampen, Tara Moens, Martijn Wehrens, Bas Molenaar, Cornelis J.J. Boogerd, +6 more
45citations -
Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Richard Drexler, Robin Khatri, Thomas Sauvigny, Malte Mohme, Cécile L. Maire, Alice Senta Ryba, +36 more
10citations -
Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Bilal Unal, Omer F. Kuzu, Yang Jin, Wanja Kildal, Manohar Pradhan, Sonia H.Y. Kung, +7 more
40citations -
Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy2020 Disease Models & Mechanisms article Medicine Aortic Disease and Treatment Approaches Open access
Joshua Craiger Peterson, Lambertus J. Wisse, Valerie Wirokromo, Tessa van Herwaarden, Anke M. Smits, Adriana C. Gittenberger–de Groot, +4 more
19citations -
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, +16 more
1citations -
P079 High-dimensional mass cytometry after local MSC treatment in patients with refractory proctitis shows an effect on the myeloid compartment: preliminary data2020 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Laura F. Ouboter, Marieke C. Barnhoorn, Lukas J.A.C. Hawinkels, Melissa van Pel, Jaap Jan Zwaginga, Hein W. Verspaget, +3 more
0citations -
Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation2024 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Megan Mulholland, Marie A.C. Depuydt, Gabriel Jakobsson, Irena Ljungcrantz, Andrietta Grentzmann, Fong To, +11 more
25citations