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Multi‐omic profiling of isogenic ApoE3/3 and ApoE4/4 iPSC‐derived astrocytes uncovers altered lipid metabolism and mitochondrial function of ApoE4 astrocytes2023 Alzheimer s & Dementia article Medicine Alzheimer's disease research and treatments Open access
Sascha Koppes, Femke M. Feringa, Aiko Robert, Iris Daphne Kruijff, Damien Olivier‐Jimenez, Lena Erlebach, +6 more
0citations -
Local YB-1, Epo, and EpoR concentrations in fractured bones: results from a porcine model of multiple trauma2023 European journal of medical research article Medicine Erythropoietin and Anemia Treatment Open access
Felix Bläsius, Johannes Greven, Weijun Guo, Eftychios Bolierakis, Zhizhen He, Cavan Lübke, +3 more
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SAHA increases chaperone expression and reduces Z-alpha-1-antitrypsin polymers in a patient specific iPSC-based liver model for alpha-1-antitrypsin deficiency2026 Stem Cell Research & Therapy article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression2021 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access cited by 2 patents
Urmo Võsa, Annique Claringbould, Harm-Jan Westra, Marc Jan Bonder, Patrick Deelen, Biao Zeng, +88 more
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Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 1 patent
Daniel Dimitrov, Dénes Türei, Martín Garrido‐Rodríguez, Paul L Burmedi, James Shiniti Nagai, Charlotte Boys, +7 more
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Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data2020 Genome biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Christian H. Holland, Jovan Tanevski, Javier Perales-Patón, Jan G. Gleixner, Manu P. Kumar, Elisabetta Mereu, +6 more
367citations -
The reductive glycine pathway allows autotrophic growth of Desulfovibrio desulfuricans2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Microbial metabolism and enzyme function Open access
Irene Sánchez‐Andrea, Iamê Alves Guedes, Bastian Volker Helmut Hornung, Sjef A. Boeren, Christopher E. Lawson, Diana Zita Sousa, +3 more
317citations -
Explainable multiview framework for dissecting spatial relationships from highly multiplexed data2022 Genome biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Jovan Tanevski, Ricardo O. Ramirez Flores, Attila Gábor, Denis Schapiro, Julio Sáez-Rodríguez
291citations -
High-dimensional single-cell analysis of human natural killer cell heterogeneity2024 Nature Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Lucas Rebuffet, Janine E. Melsen, Bertrand Escalière, Daniela Basurto-Lozada, Avinash Bhandoola, Niklas K. Björkström, +21 more
278citations -
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain2021 Nature Communications article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access cited by 1 patent
Anoushka Joglekar, Andrey D. Prjibelski, Ahmed Essam Mahfouz, Paul G. Collier, Susan Lin, Anna Katharina Schlusche, +24 more
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GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-192023 Nature article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Erola Pairo‐Castineira, Konrad Rawlik, Andrew D. Bretherick, Ting Qi, Yang Wu, Isar Nassiri, +84 more
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Comparative transcriptomics reveals human-specific cortical features2023 Science article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Nikolas L. Jorstad, Janet H. T. Song, David Exposito-Alonso, Hamsini Suresh, Nathan Castro-Pacheco, Fenna M. Krienen, +37 more
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RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response2020 Scientific Reports article Medicine Tuberculosis Research and Epidemiology Open access cited by 2 patents
Adam Penn‐Nicholson, Stanley Kimbung Mbandi, Ethan G. Thompson, Simon C. Mendelsohn, Sara Suliman, Novel N. Chegou, +83 more
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Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy2024 Cancer Cell article Immunology and Microbiology Immune cells in cancer Open access cited by 1 patent
Marit J van Elsas, Jim Middelburg, Camilla Labrie, Jessica P Roelands, Gaby Schaap, Marjolein Sluijter, +9 more
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